Otay Mesa
San Diego
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
Crossing Borders: Tijuana Day Trip from San Diego
Crossing Borders: Tijuana Day Trip from San Diego
Stand up Paddle Board Lesson on The San Diego Bay
From Tijuana: Valle de Guadalupe Private Winery Tour
Top hotels in Otay Mesa
Paradise Point Resort & Spa
the beds are awful
Reviewed on Mar 9, 2026
Best Western Seven Seas
Satisfied with the stay and everything was clean.
Reviewed on Mar 9, 2026
Hard Rock Hotel San Diego
Everything was as described
Reviewed on Mar 9, 2026
The DEXTRO Little Italy, BW Premier Collection
Front desk was often vacant.
Reviewed on Mar 9, 2026
Days Inn by Wyndham San Diego Hotel Circle
Rooms were modern and comfy. Nice pool area. Lounge with coffee in the morning. Helpful staff. Good location.
Reviewed on Mar 9, 2026
Handlery Hotel
The rooms need updating. Carpet is disgusting. Love the little patio but need screens. Pool area is very nice.
Reviewed on Mar 9, 2026
Other neighbourhoods around Otay Mesa
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
