Otay Mesa Hotels near San Diego

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Our top choices for Otay Mesa hotels

Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1572)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is P7,006
P7,970 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1008)
"Clean, convenient location "
United States
Mary
The price is P5,807
P6,605 total
includes taxes & fees
Jan 11 - Jan 12
Quality Suites San Diego Otay Mesa
3 outdoor pools, cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.7 km from Otay Mesa
9.2 out of 10, Wonderful, (1652)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort
Exterior
Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon
3.0 star property
26.3 km from Otay Mesa
9.2 out of 10, Wonderful, (1002)
"Great staff clean room very good service "
United Kingdom
Luma Anoer Waddi
The price is P8,784
P9,679 total
includes taxes & fees
Jan 11 - Jan 12
Courtyard by Marriott San Diego El Cajon
Outdoor pool
SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (549)
"Very good stay experience!"
United States
Ceabert
The price is P10,068
P11,094 total
includes taxes & fees
Jan 18 - Jan 19
SpringHill Suites by Marriott Chula Vista Eastlake
Lobby
Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista
3.0 star property
7.6 km from Otay Mesa
9.4 out of 10, Exceptional, (533)
"Clean rooms, friendly staff, and an all around great stay."
United States
Mark
The price is P11,142
P12,278 total
includes taxes & fees
Jan 4 - Jan 5
Residence Inn by Marriott San Diego Chula Vista
Lobby lounge
Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
6.6 km from Otay Mesa
9.8 out of 10, Exceptional, (1118)
"Cozy room, ver nice staff and in a great location to restaurants and shopping. "
United States
Amanda
The price is P12,011
P13,235 total
includes taxes & fees
Jan 3 - Jan 4
Ayres Hotel San Diego South - Chula Vista
Outdoor pool, pool umbrellas, sun loungers
Heritage Inn La Mesa

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
24.3 km from Otay Mesa
7.0 out of 10, Good, (1221)
"room was clean and staff very friendly"
United States
Charles
The price is P3,728
P4,112 total
includes taxes & fees
Jan 4 - Jan 5
Heritage Inn La Mesa
Outdoor pool, pool umbrellas, sun loungers
Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
2.5 star property
24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1338)
"Great room and rate"
United States
Kimberly
Lamplighter Inn & Suites at SDSU
Desk, laptop workspace, iron/ironing board, free WiFi
Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.1 km from Otay Mesa
7.8 out of 10, Good, (1561)
"Great relaxing stay "
United States
Gustavo
The price is P5,955
P6,551 total
includes taxes & fees
Jan 8 - Jan 9
Best Western Chula Vista/Otay Valley Hotel
Exterior
La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
13 km from Otay Mesa
8.6 out of 10, Excellent, (1500)
"Everything was great, staff , Room , clean , great place to stay "
United States
Luis
The price is P5,455
P6,000 total
includes taxes & fees
Jan 13 - Jan 14
La Quinta Inn by Wyndham San Diego Chula Vista
Lobby
Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
13 km from Otay Mesa
8.2 out of 10, Very Good, (1272)
"Great hotel"
United States
Rafael
The price is P5,948
P6,555 total
includes taxes & fees
Jan 18 - Jan 19
Comfort Inn Chula Vista San Diego South
Front of property
Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
14.4 km from Otay Mesa
7.2 out of 10, Good, (2031)
"Great stay"
United States
Bobby
The price is P3,678
P4,046 total
includes taxes & fees
Jan 5 - Jan 6
Hotel Palmeras Chula Vista
Property amenity
Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley
3.5 star property
28.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1004)
"Clean, convenient, great property "
United States
Dana
The price is P7,369
P8,470 total
includes taxes & fees
Jan 5 - Jan 6
Springhill Suites San Diego Mission Valley
Exterior
Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
14.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1005)
"Clean, friendly, and the breakfast was amazing! "
United States
ANDREW J
The price is P6,965
P7,662 total
includes taxes & fees
Jan 4 - Jan 5
Holiday Inn Express San Diego South - Chula Vista by IHG
Exterior
Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
13.6 km from Otay Mesa
8.6 out of 10, Excellent, (1341)
"Nice breakfast "
United States
Marcos
The price is P4,952
P5,457 total
includes taxes & fees
Jan 7 - Jan 8
Hercor Hotel - Urban Boutique
Private kitchenette
Berkshire Motor Hotel

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very Good, (1002)
"Great spot"
United States
Alexandro
The price is P4,823
P5,438 total
includes taxes & fees
Jan 4 - Jan 5
Berkshire Motor Hotel
View from room
The Rambler

The Rambler

The Rambler
3.0 star property
14.8 km from Otay Mesa
9.2 out of 10, Wonderful, (2020)
"Absolutely amazing stay will def be coming back!"
United States
Victor
The price is P6,241
P7,221 total
includes taxes & fees
Jan 8 - Jan 9
The Rambler
Outdoor pool, cabanas (surcharge), pool umbrellas
Sun Outdoors San Diego Bay

Sun Outdoors San Diego Bay

Sun Outdoors San Diego Bay
2.0 star property
15 km from Otay Mesa
10.0 out of 10, Exceptional, (82)
"Loved can’t wait to stay here again!"
United States
Carolina
The price is P11,075
P14,125 total
includes taxes & fees
Jan 14 - Jan 15
Sun Outdoors San Diego Bay
Pillowtop beds, in-room safe, desk, laptop workspace
Best Western Americana Inn

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1214)
"Staff was very courteous and room was well cleaned"
United States
Francisco
The price is P6,456
P7,343 total
includes taxes & fees
Jan 11 - Jan 12
Best Western Americana Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Gaslamp Quarter which includes signage, a bar and night scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a sandy beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park which includes a garden and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa Hotel Reviews

The Dana on Mission Bay

The Dana on Mission Bay

10/10 Excellent
"The staff were great, the restaurant was wonderful, the pools were awesome. Loved the location and the rooms. "
Amanda 3-night trip
Posted 9 hours ago
The Dana on Mission Bay

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.
What is there to do in this San Diego neighborhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.