Otay Mesa
San Diego
Visit Otay Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Things to do
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Tijuana Downtown Self Guided Walking Tour
From Tijuana: Valle de Guadalupe Shared Winery Tour
Crossing Borders: Tijuana Day Trip from San Diego
Tijuana: Guided City Tour with Local Food and Beer Tasting
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"Elevator it working properly"
Reviewed on Jun 8, 2026
Manchester Grand Hyatt San Diego
"Fantastic place, staff was excellent and location next to sea port village was amazing"
Reviewed on Jun 9, 2026
The Sofia Hotel
"This hotel was so cute. The lobby to the rooms to the restaurant in the front were all adorable. Ian & Martha at the front desk were awesome! And Mark at the Bar was amazing. The room was great and the microwave and fridge are always awesome to have in a room. I stayed in a renovated room on the ..."
Reviewed on Jun 10, 2026
Best Western Seven Seas
"Great staff. Clean beds, nice pool, nice hot tubs...one is away from the pool..extra nice."
Reviewed on Jun 10, 2026
Wyndham San Diego Bayside
"We stayed here to celebrate our 28th anniversary. The pros: Amazing views from the 10th floor facing the San Diego Bay. We were able to check in a couple hours early and the parking was close to the room. The shower was also very nice. The cons: the parking, it was way overpriced at $50 a night and ..."
Reviewed on Jun 9, 2026
Hard Rock Hotel San Diego
"Great place"
Reviewed on Jun 10, 2026
Where to stay in Otay Mesa
Downtown San Diego
Petco Park and USS Midway Museum are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Lyceum Theatre is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
