Otay Mesa
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tijuana Downtown Self Guided Walking Tour
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
San Diego: Private Luxury Gondola Cruise in Coronado
The most fun wine tour of the Guadalupe Valley
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Manchester Grand Hyatt San Diego
"Would absolutely stay again!"
Reviewed on Sep 8, 2026
Paradise Point Resort & Spa
"What a great facility for families. The rooms are spacious and comfortable. The ammenities are wonderful for kids, with lots of things for them to do to stay entertained. The views are gorgeous, and the bayfront rooms allow easy access to the beach at any point. We'll definitely be back with family ..."
Reviewed on Sep 8, 2026
Wyndham San Diego Bayside
"The hotel was clean and the service was good; we will return next time"
Reviewed on Sep 8, 2026
The Sofia Hotel
"Small room but that is to be expected for a building from the early 1900’s. It was comfortable and in a convenient area for what we wanted to do while in San Diego. Needs some upkeep but overall a good experience."
Reviewed on Sep 8, 2026
Hard Rock Hotel San Diego
"The staff were amazing! Great bar and clean room well equipped!"
Reviewed on Sep 8, 2026
Where to stay in Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Ocean Beach
Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.
