Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Fuerte Amador Resort & Marina
Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.
Miraflores Locks
Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's shops, or seek out its local tours.
Things to do
City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Half day of Panama city and canal tour: shared and private
Panama City Visit an Indian town Embera and waterfall with lunch
Day Tour in San Blas Islands All Included Visiting 4 Islands
Private or Small Group Panama Canal & City Half-Day Tour
Top hotels in Santa Ana
Casco View Apartments
Room was clean large and great to have kitchen and laundry in the unit. The pool is small and not really a lounging area. Overall it was super loud, dogs barking, alarms going off and immediate area a little sketch
Reviewed on Oct 27, 2025
Hotel Riu Plaza Panama
Great choices of Latin and European food options.
Reviewed on Nov 3, 2025
Crowne Plaza Panama Airport by IHG
Not my first nor my last stay
Reviewed on Nov 2, 2025
Megapolis Hotel Panamá
Room was excellent
Reviewed on Nov 2, 2025
Dreams Playa Bonita Panama - All Inclusive
Room was cleaned and stocked everyday
Reviewed on Nov 1, 2025
Waldorf Astoria Panama
Upon arrival to the Waldorf, Edgar was right there to assist us with our luggage to the room. It was at that moment I knew the W.A. hospitality was about to be extraordinary.
Reviewed on Oct 22, 2025
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Ancon Hill.
Calidonia
You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.
Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.
