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Santa Ana Hotels near Panama City

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Our top choices for Santa Ana hotels

1. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
8.0 out of 10, Very good, (19 reviews)
"great staff"
United States
Keith
The price is P2,413
P2,654 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Caracas - Casco Viejo

2. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (108 reviews)
"It is a new place, an apartment was in pristine condition. The building is 2 blocks away from the old town."
United States
Arshak Andrew
The price is P4,952
P7,326 total
includes taxes & fees
Oct 12 - Oct 13
Casco View Life Residences

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (197 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is P1,832
P5,774 total
includes taxes & fees
Oct 8 - Oct 9
Hotel República

4. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (75 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is P1,839
P2,023 total
includes taxes & fees
Oct 20 - Oct 21
Hostal La Cigarra

5. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (13 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel

6. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (19 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is P4,482
P6,657 total
includes taxes & fees
Oct 11 - Oct 12
La Manzana Barrio Vivo by Wynwood

7. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
Hotel Riazor

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is P6,603
P7,264 total
includes taxes & fees
Oct 8 - Oct 9
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (6,033 reviews)
"Clean rooms, amazing staff and good breakfast"
United States
Avanel
The price is P8,283
P9,112 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Riu Plaza Panama

10. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,235 reviews)
"I love the breakfast with it's increible view of the bay"
United States
Milton
The price is P6,802
P6,802 total
includes taxes & fees
Oct 21 - Oct 22
Plaza Paitilla Inn Hotel

11. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.1 km from Santa Ana
9.8 out of 10, Exceptional, (756 reviews)
"Amazing service and beautiful hotel"
United States
Jose
The price is P22,034
P24,238 total
includes taxes & fees
Nov 3 - Nov 4
Sofitel Legend Casco Viejo, Panama City

12. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,274 reviews)
"great location, great hotel"
United States
Sandra
The price is P5,568
P6,125 total
includes taxes & fees
Oct 21 - Oct 22
The Executive Hotel

13. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (460 reviews)
"The hotel was a great surprise. Great friendly knowledgeable staff. Super modern room with great decor. Massive comfortable bed."
United States
Eric
The price is P9,588
P10,547 total
includes taxes & fees
Oct 28 - Oct 29
Hotel San Felipe

14. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
"Great location and nice hotel."
United States
Olga
The price is P12,496
P13,746 total
includes taxes & fees
Oct 13 - Oct 14
Central Hotel Panama Casco Viejo

15. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.6 out of 10, Excellent, (1,770 reviews)
"Nice place, great pool area and great central location.."
United States
benjamin
The price is P8,720
P8,720 total
includes taxes & fees
Oct 21 - Oct 22
Megapolis Hotel Panamá

16. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (819 reviews)
"Beautiful hotel"
United States
Ashleigh-Ann
The price is P11,228
P12,351 total
includes taxes & fees
Oct 12 - Oct 13
American Trade Hotel

17. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (2,089 reviews)
"Very large suites, comfortable beds, great A/C"
United States
Willis
The price is P3,704
P4,074 total
includes taxes & fees
Oct 8 - Oct 9
Principe Hotel and Suites

18. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
El Cangrejo, 3.8 km from Santa Ana
8.8 out of 10, Excellent, (1,030 reviews)
"Excellent service by the staff, nice atmosphere and good ambiance"
United States
Hector
The price is P5,341
P5,875 total
includes taxes & fees
Oct 8 - Oct 9
Riande Urban Hotel

19. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 3.5 km from Santa Ana
9.0 out of 10, Wonderful, (1,179 reviews)
"Breakfast was excellent"
United States
kevin
The price is P5,591
P9,595 total
includes taxes & fees
Oct 11 - Oct 12
Waymore Hotel Spa & Casino

20. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 5.1 km from Santa Ana
9.6 out of 10, Exceptional, (1,374 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is P6,296
P6,926 total
includes taxes & fees
Oct 10 - Oct 11
Ramada Plaza by Wyndham Panama Punta Pacifica
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.
Casco View Life Residences
4.0 star property
9.0
Wonderful
108 reviews
View
A hotel corridor with a wooden door, a number plaque, and a railing.
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
19 reviews
View
An indoor dining area with tables and chairs, a mural on the wall, and hanging plants.
Hostal La Cigarra
2.0 star property
7.6
Good
75 reviews
View
A modern hotel room with a large bed, a sofa, a TV, and a view of the city.
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
19 reviews
View
A hotel room with a large bed, a window with curtains, a city view, and a lamp.
Hotel República
2.0 star property
6.8
197 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Historic Charm: Explore the iconic Santa Ana Church and immerse yourself in the area’s rich history and culture.
  • Free Walking Tours: Join a free walking tour to discover the hidden gems and local stories of Santa Ana.
  • Vibrant Local Culture: Experience the lively atmosphere and friendly locals that embody the spirit of Panama.
  • Scenic Outdoor Areas: Enjoy picturesque surroundings in the captivating San Miguel area, perfect for leisurely strolls.
  • Diverse Accommodation: Choose from a range of comfortable hotels and charming apartments tailored to various traveller needs.

Find great hotels near Santa Ana

Explore a delightful range of hotel accommodations in Santa Ana, Panama City, where you can find both comfortable hotels and charming apartments. Catering to various travellers, the area boasts pet-friendly and business-centric options, ensuring a memorable city-themed vacation. Whether you seek Panama vacation rentals or prefer established hotels like Hotel El Panama, you’ll discover the ideal base for your Panamanian adventure in this vibrant province.

  • Central Hotel Panama Casco Viejo: Central Hotel Panama Casco Viejo offers a romantic and spa-themed escape, boasting a prime city-centre location just 805m from Santa Ana. This 4-star hotel, rated 9.2 by guests, features enticing romance packages and a range of amenities designed for relaxation. Guests can indulge in 24-hour room service and special ChampagneService, perfect for intimate evenings. The outdoor pool, steam room, and on-site spa provide a tranquil retreat for couples seeking rejuvenation together. With its charming ambiance, this hotel is an idyllic choice for those looking to blend romance with city exploration.
  • American Trade Hotel: With a guest rating of 9.4 and situated a mere 644m from Santa Ana, the 4.5-star American Trade Hotel is an excellent option for families and adventure seekers alike. This hotel is not only known for its romantic atmosphere but also offers a variety of exciting activities such as hiking, biking, and Segway tours nearby. The outdoor pool, complete with sun loungers, invites relaxation, while the on-site dining with garden views provides a delightful culinary experience. Amenities for children ensure that families are well catered for, making this hotel a versatile choice for travellers.
  • Sofitel Legend Casco Viejo, Panama City: The epitome of luxury, the 5-star Sofitel Legend Casco Viejo, Panama City, is located 1km from Santa Ana and boasts an impressive guest rating of 9.8. Ideal for business travellers and those seeking a high-end spa experience, this hotel features opulent treatment rooms for massages and detoxification wraps, alongside serene outdoor treatment areas. The stylish pool area with sun loungers invites relaxation, while the sophisticated ambience sets the stage for an upscale getaway. This hotel promises a blend of sophistication and comfort in a vibrant city setting.

Where to stay near Santa Ana

Santa Ana, nestled in the vibrant Panamá Province, offers a delightful blend of family-friendly and business-friendly atmospheres. Visitors can immerse themselves in the lively Panamanian vibe while exploring nearby attractions that showcase the region's charm. From friendly locals to relaxing spots, Santa Ana is the perfect base for discovering the best parts of Panama, making it an ideal destination for any traveller seeking both adventure and comfort.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis that serves as a gateway to diverse experiences. Santa Ana is nestled within this dynamic city, which sees a steady influx of travellers year-round, especially during peak months like January, July, and September. Visitors flock here for family, city-themed, and business experiences. The city boasts an array of shopping centres and malls, making it a haven for retail therapy. Don’t miss exploring the nearby beaches and parks, offering a refreshing escape from the urban hustle.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a historic neighbourhood brimming with charm and character. This UNESCO World Heritage site is known for its cobblestone streets, colonial architecture, and lively atmosphere. Like Panama City, it attracts a diverse crowd of visitors throughout the year, particularly in January and during the spring months. Casco Viejo is a great spot for family outings, shopping, and enjoying local cuisine in its many restaurants. Here, you can stroll along the waterfront and soak in the stunning views of the Pacific Ocean.
  • San Felipe: Also located a short 644m from Santa Ana, San Felipe is another enchanting neighbourhood that offers a unique blend of history and modernity. With peak visitor numbers in February to March and December, this area is popular for family and city-themed experiences. San Felipe features vibrant shopping areas and luxury resorts, making it a perfect destination for those seeking leisure and exploration. The neighbourhood is close to picturesque parks and scenic streets, perfect for leisurely walks and immersing yourself in the local culture.

Things to do near Santa Ana

Shopping

Only a short walk from the main square, you can explore the vibrant Mercado de Santa Ana, where local artisans sell handmade crafts and souvenirs. Nearby, the Albrook Mall offers a variety of shops, featuring both international brands and local products, ideal for unique gift shopping.

Recreation

Experience tranquility at the Santa Ana Wellness Centre, offering yoga classes and holistic therapies in a serene setting. Enjoy leisurely strolls through Parque de Santa Ana, where lush greenery and peaceful pathways encourage relaxation and reflection amidst the vibrant atmosphere of the city.

Adventure

Gatun Eco Adventures offers an exhilarating zipline ropes course located 48km from Santa Ana. Experience the thrill of soaring through lush treetops while enjoying panoramic views of the surrounding rainforest, making it an ideal spot for adventure seekers looking to embrace nature's beauty.

Nightlife

Explore the vibrant nightlife in Santa Ana by visiting the lively La Tana, known for its delicious tapas and cocktails. For a more laid-back vibe, head to Casa de la Cerveza to sample a variety of local brews while enjoying the relaxed atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

When planning your visit to Santa Ana, consider travelling between September and November for lower accommodation prices, as opposed to the pricier months of January and March to April. Tuesdays offer the best hotel rates, while Saturdays are the most expensive. Use Expedia’s search tool to filter results by budget and hotel type, including eco-friendly options. To save further, combine your hotel bookings with flights and activities in a package deal. Keep an eye out for Expedia coupons to maximise your savings while exploring the local area.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to set your budget, preferred location, and other criteria. You can organise your results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you can refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can optimise your travel budget by combining your hotel reservation in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana, a charming district in Panama City, offers a delightful blend of family-friendly and cultural experiences. Notable attractions include the historic Santa Ana Church and the captivating San Miguel area, perfect for those seeking outdoor scenery and local history. This vibrant locale is ideal for both business and leisure travellers looking to immerse themselves in the rich culture and heritage of Panama.

  • Metropolitan Cathedral of Panama: This stunning cathedral showcases a blend of architectural styles, reflecting the rich cultural heritage of Panama. Located 805m from Santa Ana, its majestic façade and intricate interiors invite visitors to explore its historical significance and serene atmosphere.
  • Interoceanic Canal Museum: Situated 805m away, this museum offers an insightful journey through the history of the Panama Canal. Engaging exhibits reveal the challenges and triumphs of its construction, making it an enlightening stop for history enthusiasts.
  • Independence Square: A vibrant piazza located 805m from Santa Ana, Independence Square is a hub of cultural activity. Surrounded by historical buildings, it provides a picturesque setting to experience local life and events.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Reaching Santa Ana in Panama City is convenient, with three major airports nearby. Marcos A. Gelabert International Airport (PAC) is located 3km from Santa Ana, with luxurious hotels like Hilton Panama and W Panama offering various transportation services, including 24-hour airport shuttles. Balboa Pacifico International Airport (BLB) is 6km away, featuring top-tier accommodations like The Westin Playa Bonita Panama, while Tocumen International Airport (PTY) is 21km distant, with options such as The Santa Maria, A Luxury Collection Hotel providing accessible transport services. Each airport presents excellent choices for lodging and seamless access to your destination.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Hotel Caracas - Casco Viejo is one of the top choices for your stay in Santa Ana. This hotel is a short 7-minute walk from Avenida Balboa, and it offers a restaurant and a bar. Another good choice for your stay in the area is Casco View Life Residences.
How many hotels can I expect to find in Santa Ana?
Expedia has 135 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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