Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
Panama Viejo
Find out about the history of Panama City with a stop at Panama Viejo. Stroll along the seaside in this vibrant area, or check out its top-notch restaurants.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Things to do
City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Panama City Visit an Indian town Embera and waterfall with lunch
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Visit San Blas Paradise: Day Tour to 4 Islands with Lunch & Drink
Top hotels in Santa Ana
Casco View Apartments
The building is great, the apartment was perfect, the staff superbe, and they take care of the building, guests and security. There is a supermarket across the street which makes your life so much easier. The issue, as others have mentioned, is that the building is at the limit of the safe area in ...
Reviewed on Apr 29, 2026
Hotel Riu Plaza Panama
The best experience! Thank you!
Reviewed on May 10, 2026
Crowne Plaza Panama Airport by IHG
Convenient location if you need to spend the night waiting for your connection. Its overpriced in terms of the quality of the hotel. However there are not other options nearby
Reviewed on May 9, 2026
The Executive Hotel
I stayed for a week and had breakfast everyday except on the last day due to an early departure ..what i liked about the breakfast was that it was a different selection everyday
Reviewed on May 8, 2026
Principe Hotel and Suites
Room was old and tired, stains on walls and furniture, drapes had holes , windows were dirty so you can’t enjoy the view, no coffee pot and when I asked for one they told me NO , even as my original booking said I had a tea and coffee pot , typical where hotels.com ( Expedia group ) and the hotel ...
Reviewed on May 9, 2026
Dreams Playa Bonita Panama - All Inclusive
The staff were great. The resorts needs updating. The breakfast buffet was good but the Ala carte restaurants were not so good.
Reviewed on May 9, 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Maracana Stadium.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
