Santa Ana

Panama City

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Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
Stay at this condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera are located ...
9.2/10 Wonderful! (54 reviews)
Room was clean large and great to have kitchen and laundry in the unit. The pool is small and not really a lounging area. Overall it was super loud, dogs barking, alarms going off and immediate area a little sketch

Reviewed on Oct 27, 2025

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is P6,422 per night from Jan 12 to Jan 13
P6,422
P7,064 total
Jan 12 - Jan 13, 2026
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,696 reviews)
No worries. Outstanding in every aspects. Room, food, personnel, pool, location.

Reviewed on Dec 21, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is P6,459 per night from Dec 24 to Dec 25
P6,459
P7,105 total
Dec 24 - Dec 25
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,321 reviews)
Place has a contemporary stylish design. Staff was very helpful and friendly. Hallways and room have a mildew odor and I could not lower the temperature in the room. Furthermore, the room has everything you might need. I suggest providing some bathrobes.

Reviewed on Dec 20, 2025

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is P7,437 per night from Jan 9 to Jan 10
P7,437
P8,181 total
Jan 9 - Jan 10, 2026
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (993 reviews)
Yes

Reviewed on Dec 11, 2025

Sheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is P8,746 per night from Dec 23 to Dec 24
P8,746
P9,621 total
Dec 23 - Dec 24
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,291 reviews)
Big rooms, excellent food choices

Reviewed on Dec 20, 2025

Megapolis Hotel Panamá
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is P9,479 per night from Jan 13 to Jan 14
P9,479
P10,427 total
Jan 13 - Jan 14, 2026
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
It was a very nice stay. The room is nice, organized and clean with a great view of the city. The blankets are a little too warm and we wished for a lighter blankets. Breakfast buffet was very good with many food choices and best custom eggs cooked tailored to our demands. Uber to Casco Viejo was ...

Reviewed on Dec 15, 2025

Las Americas Golden Tower Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Casco Viejo
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San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Ancon Hill.

El Chorrillo
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Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
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Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Ancon Hill, a few notable attractions nearby.

Balboa
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Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu


Santa Ana