Top 10 Hotels Near El Machetazo Santa Ana in Panama City for 2026

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Our top choices for El Machetazo Santa Ana hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

A room with a large window, a television mounted on the wall, and two chairs.

A four-poster bed with a black and white bedspread, two bedside tables with lamps, and a robe hanging on a rack.

1. La Isabela Suites

San Felipe, 0.3 km from El Machetazo Santa Ana

David

P9,864

P10,851 total

includes taxes & fees

Oct 2 - Oct 3

A multi-story building with ornate balconies, large windows, and decorative moldings.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

2. Hotel Plaza Herrera

San Felipe, 0.4 km from El Machetazo Santa Ana

Christina

P12,811

P14,092 total

includes taxes & fees

Sep 25 - Sep 26

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

San Felipe, 0.8 km from El Machetazo Santa Ana

Jose

P24,835

P27,319 total

includes taxes & fees

Oct 5 - Oct 6

A restaurant with multiple dining tables, chairs, and a central water feature.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

A bar area with multiple seating options, a bar counter, and a fireplace.

4. Hotel La Compañía Casco Antiguo

San Felipe, 0.5 km from El Machetazo Santa Ana

Reid

P17,515

P19,266 total

includes taxes & fees

Sep 25 - Sep 26

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A kitchen with a glass-top table, a coffee machine, wine glasses, and a bottle of wine.

5. La Concordia Boutique Hotel

San Felipe, 0.2 km from El Machetazo Santa Ana

Jadah

P12,640

P13,904 total

includes taxes & fees

Oct 8 - Oct 9

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

6. Hotel San Felipe

San Felipe, 0.4 km from El Machetazo Santa Ana

Rebecca

P9,090

P9,999 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

A modern kitchen with white cabinets, a dining table with chairs, and a spiral staircase.

A bedroom with a large bed, a ceiling fan, and multiple windows.

A spacious living area with a large TV, a stone accent wall, and a modern kitchen in the background.

7. Casa Lefevre By Wynwood House

San Felipe, 0.5 km from El Machetazo Santa Ana

Selam

P7,930

P10,446 total

includes taxes & fees

Sep 27 - Sep 28

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

A white building with multiple balconies, large windows, and decorative railings.

8. American Trade Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

RAINIERO

P12,723

P13,996 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story building with balconies, large windows, and a clear blue sky.

An outdoor patio with a white umbrella, lounge chairs, and a tiled floor.

A hallway with a brick wall, a blue door, and a chair with a cushion.

A hotel room with a brick wall, a large window with curtains, a bed with pillows, a nightstand, and a chair.

9. Las Clementinas

San Felipe, 0.2 km from El Machetazo Santa Ana

James

P8,085

P10,146 total

includes taxes & fees

Sep 26 - Sep 27

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

An outdoor patio with a checkered floor, a bar area with cushioned seating, and a large umbrella providing shade.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

10. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 0.6 km from El Machetazo Santa Ana

Shanae

P14,797

P16,276 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story building with balconies, arched windows, and decorative railings.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A building with a balcony and a street view.

11. Central Hotel Panama Casco Viejo

San Felipe, 0.5 km from El Machetazo Santa Ana

Olga

P11,912

P13,103 total

includes taxes & fees

Sep 27 - Sep 28

A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

A modern building with a central entrance, large pillars, and a reflective pathway leading to the entrance.

A modern kitchen with a central island, a dining area with a glass table and chairs, and artwork on the walls.

A living room with a sofa, armchairs, a coffee table, a console table with a mirror, and a tall floor lamp.

12. Yoo Apartamento

Bella Vista, 2.9 km from El Machetazo Santa Ana

Kevin

P6,013

P9,370 total

includes taxes & fees

Sep 26 - Sep 27

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

A buffet setup with various dishes and utensils.

A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

13. Marriott Panama Hotel

2.4 km from El Machetazo Santa Ana

Richard

P10,585

P11,643 total

includes taxes & fees

Oct 10 - Oct 11

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

A person performing a yoga pose in a living room with a large window and a sofa.

14. Bristol Panama, a Registry Collection Hotel

Bella Vista, 3.2 km from El Machetazo Santa Ana

Juliet

P13,256

P14,581 total

includes taxes & fees

Oct 2 - Oct 3

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

15. Tantalo Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

P4,751

P5,226 total

includes taxes & fees

Sep 30 - Oct 1

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

16. Casco View Life Residences

Santa Ana, 0.2 km from El Machetazo Santa Ana

Ruben

P4,333

P6,645 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

17. Hotel Magnolia Boutique

San Felipe, 0.4 km from El Machetazo Santa Ana

Boris

P4,618

P5,080 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

A modern kitchen with a dining area, a flat-screen TV, and a view of the cityscape through the window.

A modern living room with a glass dining table, black chairs, a grey sofa, and a large window with a city view.

A modern bedroom with a bed, bedside tables, a nightstand, a wall-mounted TV, and a city view.

18. Modern Apartments at The Gray Prime Location

Campo Alegre, 3 km from El Machetazo Santa Ana

Tiyania

P5,124

P5,637 total

includes taxes & fees

Sep 25 - Sep 26

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A balcony with a view of a city skyline, a river, and a large tree.

19. Hotel Bardot Boutique

San Felipe, 0.8 km from El Machetazo Santa Ana

Gary

P5,043

P5,548 total

includes taxes & fees

Oct 11 - Oct 12

A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.

A high-rise building with a rooftop pool area, surrounded by other buildings.

A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

20. W Panama

Campo Alegre, 3.2 km from El Machetazo Santa Ana

Nikkia

P13,478

P14,826 total

includes taxes & fees

Oct 10 - Oct 11

View all properties

Compare popular hotels close to El Machetazo Santa Ana

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 48 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 751 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 351 reviews	View
La Concordia Boutique Hotel	9.6 Exceptional 237 reviews	View

Top El Machetazo Santa Ana Hotel Reviews

American Trade Hotel

10/10 Excellent

"Right from the beginning the staff was extremely helpful and polite. The room had a great view, it was clean and very comfortable."

Hotel Caracas - Casco Viejo

10/10 Excellent

"We stayed one night there. Very comfortable location. The room was clean, nice shower, helpful and friendly staff, and they have good coffee in the lobby :)"

Hostal La Cigarra

8/10 Good

"Location is great, very comfortable and the instructions sent before the stay were useful. The room is clean and functional, and the stuff is very kind and helpful. The only thing to say is that there is no hot water in the shower, something that I expect to be informed about before booking the room."

Hotel San Felipe

10/10 Excellent

"This property is set in a great location and is very cute and clean. The bed was great. The staff was very nice and efficient without being overwhelming. We didn't eat at the restaurant because we did a lot of exploring but would definitely stay again. The only thing I would say needs some improvement is the wifi strength it wasn't always reliable."

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

"Sofitel Legend is a wonderful place to stay. The staff are amazing."

Hotel Magnolia Boutique

10/10 Excellent

"Muy buen lugar"

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

8/10 Good

"Todo bien"

Hotel Casa Panamá

8/10 Good

"Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance."

La Concordia Boutique Hotel

10/10 Excellent

"Location was excellent, in the thick of things in Casco Viejo and walking distance to a wide variety of shops and restaurants. The rooftop restaurant was very nice though we didn’t eat there. Our room was large, with a huge bathroom, huge shower, and double sinks. Decor was wonderful. Highly recommended."

Other attractions near El Machetazo Santa Ana

Amador Theater

Enjoy a show at Amador Theater, a storied theater in Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Iglesia de la Merced

You can learn about the history of Panama City with a stop at Iglesia de la Merced. Check out the shops and top-notch restaurants in this vibrant area.

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Danilo Perez Foundation

Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area.

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Museo de la Esmeralda

You can spend time exploring the galleries in Museo de la Esmeralda during your trip to Panama City. You can enjoy the bars while in the area.

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Palacio de las Garzas

You can study the exhibits at Palacio de las Garzas, a museum with a storied past, during your trip to Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Metropolitan Cathedral of Panama

9.0/10 (793 reviews)

Metropolitan Cathedral of Panama is just one of the places to see in Panama City, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this vibrant area.

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Independence Square

9.0/10 (62 reviews)

You can learn about the history of Panama City with a stop at Independence Square. Check out the shops and top-notch restaurants in this vibrant area.

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Frequently asked questions

What's the area like around El Machetazo Santa Ana?

El Machetazo Santa Ana is located in Panama City. If you're looking for a convenient place to stay, check out the 517 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to El Machetazo Santa Ana?

Adjacent to El Machetazo Santa Ana, Hotel Casa Panamá is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and a nightclub. Other good options close by include Central Hotel Panama Casco Viejo and Sofitel Legend Casco Viejo, Panama City.

How many hotels are there close to El Machetazo Santa Ana?

Expedia has 517 hotels and other accommodations within a mile from El Machetazo Santa Ana.

If I need to cancel the hotel reservation for my stay near El Machetazo Santa Ana, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best options available near El Machetazo Santa Ana.

What can I see and do near El Machetazo Santa Ana?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Mola Museum. Explore landmarks like Iglesia del Carmen, Panama Canal Railway, and Iglesia de la Merced. You can check out the local talent at National Theater, Amador Theater, and Anita Villalaz Theater.

Hotels near El Machetazo Santa Ana

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for El Machetazo Santa Ana hotels

1. La Isabela Suites

2. Hotel Plaza Herrera

3. Sofitel Legend Casco Viejo, Panama City

4. Hotel La Compañía Casco Antiguo

5. La Concordia Boutique Hotel

6. Hotel San Felipe

7. Casa Lefevre By Wynwood House

8. American Trade Hotel

9. Las Clementinas

10. Amarla Boutique Hotel Casco Viejo Adults Only

11. Central Hotel Panama Casco Viejo

12. Yoo Apartamento

13. Marriott Panama Hotel

14. Bristol Panama, a Registry Collection Hotel

15. Tantalo Hotel

16. Casco View Life Residences

17. Hotel Magnolia Boutique

18. Modern Apartments at The Gray Prime Location

19. Hotel Bardot Boutique

20. W Panama

Compare popular hotels close to El Machetazo Santa Ana

Top El Machetazo Santa Ana Hotel Reviews

American Trade Hotel

Hotel Caracas - Casco Viejo

Hostal La Cigarra

Hotel San Felipe

Sofitel Legend Casco Viejo, Panama City

Hotel Magnolia Boutique

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Hotel Casa Panamá

La Concordia Boutique Hotel

Other attractions near El Machetazo Santa Ana

Amador Theater

Iglesia de la Merced

Danilo Perez Foundation

Mola Museum

Museo de la Esmeralda

Palacio de las Garzas

Metropolitan Cathedral of Panama

Independence Square

Frequently asked questions