Santa Ana

Panama City

Plaza Santa Ana, Panama Casco Viejo
Santa Ana

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is P5,456 per night from Jun 26 to Jun 27
P5,456
P7,842 total
Jun 26 - Jun 27
includes taxes & fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
9/10 Wonderful! (99 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."

Reviewed on Jun 20, 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is P8,923 per night from Jun 30 to Jul 1
P8,923
P9,816 total
Jun 30 - Jul 1
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,648 reviews)
"It’s location."

Reviewed on Jun 24, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is P8,222 per night from Jul 20 to Jul 21
P8,222
P9,449 total
Jul 20 - Jul 21
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,609 reviews)
"👍👍Thank you for your hospitality."

Reviewed on Jun 23, 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is P18,373 per night from Jul 9 to Jul 10
P18,373
P18,373 total
Jul 9 - Jul 10
includes taxes & fees
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.6/10 Good! (1,016 reviews)
"Staff was so pleasant. Hotel needs updating and well the beach really isn’t swimmable it’s by the canal so lots of pollution’s"

Reviewed on Jun 24, 2026

Dreams Playa Bonita Panama - All Inclusive
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is P3,479 per night from Jun 26 to Jun 27
P3,479
P3,827 total
Jun 26 - Jun 27
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,907 reviews)
"Me encantó, todo estuvo muy bien, además queda muy cerca de la parada del metro que nos ayudó a movilizarnos"

Reviewed on Jun 24, 2026

Principe Hotel and Suites
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
The price is P5,442 per night from Jul 23 to Jul 24
P5,442
P5,986 total
Jul 23 - Jul 24
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (1,165 reviews)
"Good overall, had no issues."

Reviewed on Jun 23, 2026

The Executive Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.



Santa Ana