Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Things to do
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Tour to a waterfall and Embera village with lunch included
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Monkey and Sloth Jungle Habitat Panama Tour
Boat tour in the Panama Canal to Monkeys and sloths islands
Top hotels in Santa Ana
Casco View Apartments
The space was very nice.
Reviewed on Feb 1, 2026
Hotel Riu Plaza Panama
The Riu hotel in Panama City is wonderful ! The buffet breakfast is plentiful. The rooms are spacious and the location is very convenient. They have a beautiful pool and a lovely restaurant adjacent to it. I certainly don’t have any complaints !
Reviewed on Feb 6, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
All fantastic. We return year after year
Reviewed on Feb 2, 2026
Crowne Plaza Panama Airport by IHG
Clean room, acceptable dining area with good service. Pool area is great
Reviewed on Jan 29, 2026
Waldorf Astoria Panama
Room was great, excellent view, clean and spacious.
Reviewed on Jan 27, 2026
Las Americas Golden Tower Panama
Great buffet, good fitness centre. Quiet room with a great view
Reviewed on Feb 4, 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Flag of Cerro Ancón.
Calidonia
You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Flag of Cerro Ancón, a few notable attractions nearby.
Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.
