Southern Indiana Trips (flight + hotel)

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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
Louisville Science Center featuring outdoor art

West Main Historic District

West Main Historic District is beloved for its fantastic nightlife. Take some time to explore sights in the area like Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive, Clarksville, IN
Fully refundable
The price is P3,803 per night from Aug 13 to Aug 14
P3,803
P4,297 total
Aug 13 - Aug 14
includes taxes & fees
6.8/10 (2,252 reviews)
"Loved it"

Reviewed on Aug 10, 2025

Radisson Hotel Louisville North
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St, Evansville, IN
Fully refundableReserve now, pay when you stay
The price is P6,566 per night from Sep 1 to Sep 2
P6,566
P7,551 total
Sep 1 - Sep 2
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
"The room was very clean and staff was extremely friendly"

Reviewed on Aug 11, 2025

Hyatt Place Evansville
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
440 South Main St, Ferdinand, IN
Fully refundableReserve now, pay when you stay
The price is P4,830 per night from Aug 17 to Aug 18
P4,830
P5,410 total
Aug 17 - Aug 18
includes taxes & fees
6.8/10 (605 reviews)
"It was okay just didn’t have much to offer without driving."

Reviewed on Aug 7, 2025

Quality Inn & Suites
See all 1,438 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Holiday World and Splashin' Safari

Holiday World and Splashin' Safari

Every day is a holiday at this fun-filled combination theme park and water park, where visitors of all ages can explore roller coasters, raft rides and wave pools.

Holiday World and Splashin' Safari
Louisville Waterfront Park

Louisville Waterfront Park

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.

Louisville Waterfront Park

Kentucky Bourbon Trail Visitor Center

Kentucky Bourbon Trail Visitor Center is just one of the places to see in Louisville, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Kentucky Bourbon Trail Visitor Center

What to do in Southern Indiana

Group with axes for throwing in Indianapolis

30-Minute Walk-In Axe Throwing Experience Indianapolis

P1,280
per adult
100% of travellers recommend
30-Minute Walk-In Axe Throwing Experience Indianapolis
Japanese Street Food Class in Beech Grove

Japanese Street Food Class in Beech Grove

P6,078
per adult
Japanese Street Food Class in Beech Grove
See all activities in Southern Indiana

Frequently asked questions

How much does a Southern Indiana vacation package cost?
We make it simple to travel somewhere new, with Southern Indiana vacation packages starting from just . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana vacation package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1,000,000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travelers who come to see its top sights, like Churchill Downs and Muhammad Ali Center.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana vacation?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travelers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia vacation package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana vacation package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana vacation package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.