A vineyard with rows of grapevines.

Santa Cruz Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 19 - Aug 20
Tomorrow
Aug 20 - Aug 21
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Filter by

Star rating

Guest rating

Our top choices for Santa Cruz hotels

Reserve now, pay later
Hotel
Breakfast included
Bed & breakfast
Plaza de Armas

1. Santa Cruz Plaza

Santa Cruz Plaza
Santa Cruz
Canada
William
P8,033
P8,033 total
Sep 6 - Sep 7
Santa Cruz Plaza

2. Casa Calfu

Casa Calfu
Santa Cruz
Australia
Mary
P4,785
P4,785 total
Aug 24 - Aug 25
Casa Calfu

3. Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium
Santa Cruz
United States
Jose
P6,315
P6,315 total
Sep 13 - Sep 14
Hotel Boutique Vendimia Premium

4. Hotel Cava Colchagua

Hotel Cava Colchagua
Santa Cruz
Canada
Anonymous traveler
P6,806
P6,806 total
Aug 20 - Aug 21
Hotel Cava Colchagua

5. TerraViña

TerraViña
Santa Cruz
United Kingdom
DARREN
P9,222
P9,222 total
Aug 26 - Aug 27
TerraViña

6. Hotel Vendimia Parador

Hotel Vendimia Parador
Santa Cruz
United States
Pawel
P5,294
P5,294 total
Aug 20 - Aug 21
Hotel Vendimia Parador

7. Colchagua Tiny Lodge

Colchagua Tiny Lodge
Santa Cruz
United States
Jonathan
P9,443
P9,443 total
Aug 20 - Aug 21
Colchagua Tiny Lodge

8. Hotel Boutique Grand Cru

Hotel Boutique Grand Cru
Santa Cruz
United States
Jonathan
P5,993
P5,993 total
Aug 20 - Aug 21
Hotel Boutique Grand Cru

9. La Perla Hotel

La Perla Hotel
Santa Cruz
Canada
Nancy
P5,048
P5,048 total
Sep 1 - Sep 2
La Perla Hotel

10. Hostal Vida 2000

Hostal Vida 2000
Santa Cruz
United States
Kati
P2,410
P2,410 total
Aug 20 - Aug 21
Hostal Vida 2000

11. Noi Blend Colchagua

Noi Blend Colchagua
Palmilla
United States
Barbara
P10,010
P10,010 total
Aug 21 - Aug 22
Noi Blend Colchagua

12. Vik Chile

Vik Chile
San Vicente
Brazil
Rafael
P43,209
P43,209 total
Sep 13 - Sep 14
Vik Chile

13. Hotel Central

Hotel Central
San Fernando
P3,864
P3,864 total
Aug 20 - Aug 21
Hotel Central

14. Hotel Ontiveros

Hotel Ontiveros
San Fernando
Canada
Gordon
P4,435
P4,435 total
Aug 20 - Aug 21
Hotel Ontiveros

15. Hotel Viña La Playa

Hotel Viña La Playa
Peralillo
Mexico
Manuel
P16,683
P16,683 total
Aug 20 - Aug 21
Hotel Viña La Playa

16. Hacienda Histórica Marchigüe

Hacienda Histórica Marchigüe
Marchihue
United States
Anonymous traveler
P12,234
P12,234 total
Aug 21 - Aug 22
Hacienda Histórica Marchigüe
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santa Cruz attractions

Lapostolle Clos Apalta Winery

9.4/10 (21 reviews)
Carved into the hillside, Clos Apalta Winery produces award-winning Bordeaux-style wines using a gravitational system. Reserve a private tour to taste premium vintages overlooking the stunning Colchagua Valley.
See properties

Colchagua Campo y Vino

9.4/10 (3 reviews)
Immerse yourself in Chile's wine country at this boutique hotel surrounded by Colchagua Valley vineyards. Enjoy personalized service while exploring nearby wineries during harvest festivals or spring blooms.
See properties

Casino Colchagua

8.0/10 (6 reviews)
Chile's first thematic casino blends gaming with colonial-inspired decor that celebrates local heritage. Enjoy slot machines and table games while savoring Chilean cuisine from the adjacent Hotel Santa Cruz Plaza.
See properties

Laura Hartwig Winery

9.0/10 (17 reviews)
This family-run winery in Chile's Colchagua Valley specializes in premium Bordeaux-style wines. Stroll through picturesque vineyards before enjoying intimate tastings paired with local cheeses in their barrel room.
See properties

Museo de Colchagua

9.6/10 (24 reviews)
This renowned private museum houses one of Latin America's most extensive historical collections from prehistoric to modern Chile. Explore pavilions featuring indigenous artifacts and colonial treasures.
See properties

Bodega Viña Viu Manent

10.0/10 (1 review)
This historic Chilean winery stands out for its exceptional Malbec wines, a rarity in the region. Take a horse-drawn carriage through sun-dappled vineyards before sampling their acclaimed vintages.
See properties

Plaza de Armas

8.2/10 (34 reviews)
This elegant city square features symmetrical walkways and lush gardens at the heart of Santa Cruz. Relax beneath towering trees or catch local cultural events that showcase the region's vibrant community life.
See properties

Learn more about Santa Cruz

Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artifacts while the Plaza de Armas offers local crafts and regional foods on weekends.

See all hotels in Santa Cruz
A vineyard with rows of grapevines.

Top Santa Cruz Hotel Reviews

TerraViña

TerraViña

10/10 Excellent
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."
andy 2-night trip
Posted 12 days ago
TerraViña
Hotel Cava Colchagua

Hotel Cava Colchagua

10/10 Excellent
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría muy bien incluir un perchero y una pequeña mesa con dos sillas para mayor comodidad. Asimismo, en el baño eché de menos una mejor iluminación en el área del espejo. Por lo demás, todo fenomenal. El personal es sumamente amable y siempre está atento a cualquier necesidad. ¡Regresaría sin dudarlo!"
Franco 3-night trip
Posted 12 days ago
Hotel Cava Colchagua
Hotel Vendimia Parador

Hotel Vendimia Parador

10/10 Excellent
" "I had a wonderful experience at this hotel. The location is fantastic—central and convenient to everything I wanted to see. The room was spotless and well-maintained, which I really appreciated. But what truly sets this place apart is the staff. From the front desk to the housekeeping team, everyone was genuinely warm, helpful, and went out of their way to be friendly. It made all the difference. I would absolutely stay here again." "
Yorba 1-night trip
Posted 5 months ago
Hotel Vendimia Parador
Hotel Boutique Grand Cru

Hotel Boutique Grand Cru

10/10 Excellent
"Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms "
Martin 1-night trip
Posted 5 months ago
Hotel Boutique Grand Cru

More cheap stays in Santa Cruz

Hostal Vida 2000

Hostal Vida 2000

Ismael Valdes 245 Santa Cruz
P2,410
P2,410 total
Aug 20 - Aug 21
5.4/10 (3 reviews)
Hostal Vida 2000
Intown Apart Santa Cruz

Intown Apart Santa Cruz

Claudio Cancino 92 Santa Cruz O'Higgins
Get rates
10/10 Exceptional! (1 review)
Intown Apart Santa Cruz
La Ruta del Jazz

La Ruta del Jazz

Villa Yucatan Santa Cruz
Get ratesLa Ruta del Jazz
Weekend & Wine B&B

Weekend & Wine B&B

Av. 21 de mayo 0317, con Av Las Toscas, Santa cruz Libertador General Bernardo O'Higgins
Get ratesWeekend & Wine B&B
Hosteria No me Olvides

Hosteria No me Olvides

Agustin besoain 320 Curicó Maule (region)
Get ratesHosteria No me Olvides
Casa Suiza - Hostel

Casa Suiza - Hostel

Los Libertadores 199, Santa Cruz, Chile Santa Cruz Santa Cruz
Get ratesCasa Suiza - Hostel

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Scenic Outdoor Activities: Enjoy a variety of outdoor pursuits, from hiking scenic trails to surfing at local hotspots.
  • Rich Cultural Exploration: Immerse yourself in local culture by visiting historic buildings and the engaging history museum.
  • Charming Streets: Stroll through picturesque streets filled with vibrant local culture and captivating architecture.
  • Luxurious Accommodation: Choose from an array of hotels and bed & breakfasts, including winery-themed and spa retreats.
  • Enchanting Attractions: Visit notable sites like the Santa Cruz wharf and Santa Cruz de Tenerife for a memorable experience.

Find great hotels in and around Santa Cruz

Discover a charming selection of hotels and bed & breakfasts in Santa Cruz, O'Higgins Region, tailored for every type of traveller. Whether you seek a winery-themed escape, a rejuvenating spa experience, or a convenient base for business travel, Santa Cruz offers diverse accommodation options. With excellent facilities and services, you can find the perfect retreat to enhance your visit, ensuring a memorable stay in this picturesque region of Chile.

  • Santa Cruz Plaza: This charming 4-star hotel is located in the heart of Santa Cruz, boasting a welcoming atmosphere ideal for families and adventure seekers alike. With a guest rating of 8.8, Santa Cruz Plaza offers a variety of recreation activities both onsite and nearby, including sailing, surfing, rafting, and hiking. Families will appreciate the dedicated children's amenities, such as a supervised children's club and babysitting services, ensuring both fun and safety for younger guests. The combination of adventure and family-focused services makes this hotel a suitable choice for a memorable vacation experience.
  • Vik Chile: Situated approximately 16km from Santa Cruz, Vik Chile is a luxurious 5-star property with an impressive guest rating of 9.2. Emphasising adventure and relaxation, this hotel features a full spa, sauna, and outdoor pool, providing the perfect setting for unwinding after a day of horse riding or mountain biking. The elegant design and stunning surroundings offer a high-end escape, while the onsite adventure activities cater to those seeking excitement. The combination of luxury and wellness makes Vik Chile a standout option for travellers looking for an indulgent getaway.
  • TerraViña: A delightful 3-star hotel located in Santa Cruz, TerraViña enjoys a guest rating of 9.2 and is ideal for those seeking a romantic and winery-themed experience. Surrounded by picturesque vineyards, the property offers adventure activities such as hiking and horse riding, along with special romance packages featuring private winery tours and champagne services. Guests can relax by the outdoor pool or enjoy limited-hour room service, making it a charming choice for couples looking to blend adventure with intimate moments in a stunning setting.

Where to stay near Santa Cruz

Santa Cruz, nestled in the O'Higgins Region of Chile, offers a captivating blend of romance and adventure. Explore the charming streets filled with local culture or indulge in luxury at its vibrant resorts. Nearby areas promise a relaxing escape, perfect for excursions and outdoor activities. Whether you seek the lively atmosphere reminiscent of Santa Cruz, California, or the stunning vibes of South Tenerife, this region guarantees an unforgettable travel experience.

  • Colchagua Valley Wine Route: Nestled approximately 10km from Santa Cruz, the Colchagua Valley Wine Route is a delightful escape for wine lovers and outdoor enthusiasts alike. This region is renowned for its picturesque vineyards and charming wineries, making it a prime destination for a romantic getaway or an entertaining day out. With seasonal peaks from January to March, visitors can enjoy hiking trails and activities in the serene landscape. The area also boasts local landmarks like beautiful beaches and event venues, providing a perfect setting for relaxation and exploration.
  • Cunaco: Situated about 6km from Santa Cruz, the quaint village of Cunaco offers a tranquil retreat for tourists seeking an authentic Chilean experience. Like the surrounding areas, Cunaco sees a seasonal influx of visitors, particularly between January and March. The village is ideal for those interested in both history and outdoor activities, with local attractions including a history museum and access to ski fields. Whether you're in search of a romantic escape or entertaining outdoor pursuits, Cunaco provides a charming backdrop for a memorable visit.
  • Palmilla: Located 13km from Santa Cruz, the city of Palmilla is a vibrant destination that attracts visitors year-round, with peak seasons in February to March and September. Known for its outdoor experiences, Palmilla offers stunning hiking trails and ski opportunities, catering to adventure seekers. The city also features beautiful beaches and impressive event venues, making it an ideal spot for both relaxation and entertainment. With its scenic landscapes and inviting atmosphere, Palmilla promises an enjoyable experience for all types of travellers.

Things to do in Santa Cruz

Shopping

In Santa Cruz, you can explore the bustling local market, where handcrafted gifts and unique souvenirs abound. If you're up for a drive, visit the Colchagua Shopping Centre, about 24km away, featuring a variety of shops and dining options to enhance your shopping experience.

Recreation

Santa Cruz offers a variety of wellness retreats where you can indulge in relaxing spa treatments, yoga sessions, and meditation classes amidst picturesque vineyards. Explore nearby natural reserves for hiking and outdoor activities, allowing you to connect with nature and rejuvenate your spirit.

Adventure

Explore the stunning Colchagua Valley by cycling through picturesque vineyards, where you can savour local wines and enjoy breathtaking landscapes. Additionally, embark on a thrilling hike in the nearby Andes foothills, offering captivating views and a chance to encounter diverse wildlife along the trails.

Nightlife

In Santa Cruz, La Fama offers a lively atmosphere with vibrant music and dancing, while Bar de Pisco is ideal for tasting local cocktails. For a relaxed evening, enjoy the charming ambience of Cafe de la Plaza, where you can unwind and mingle with fellow visitors.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, consider visiting during the cheaper months of March, August, and December. Booking your accommodation about a month in advance often yields the best rates, and Tuesday is typically the least expensive day to stay. Utilise Expedia's search tools to compare prices and find deals, including last-minute offers. Look for package deals that combine flights and hotels for additional savings. Additionally, explore free activities in the area to enhance your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are March, August and December, where the prices are slightly lower. This is in comparison to April to May and July, where prices are slightly higher.
  • The best time to book a hotel: Booking a hotel in Santa Cruz about 1 month out from when you are planning to stay is usually when prices are lowest. If you're a little more spontaneous, you could also peruse Expedia's last minute deals for hotels, look out for the green banner below the price, as this indicates a cheaper deal.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Tuesday. The most expensive day to stay in Santa Cruz is Sunday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget, preferred location, and additional preferences. You can arrange your search results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Furthermore, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels available for booking.
  • Consider bundling your trip: You can potentially save money by combining your hotel accommodation in Santa Cruz with your flights and activities through an Expedia package deal.

Find the best attractions in and around Santa Cruz

Santa Cruz offers a delightful blend of romance and outdoor entertainment, perfect for a charming getaway. Visitors can explore its historic buildings and immerse themselves in local culture at the history museum. Noteworthy attractions include the Santa Cruz wharf and the enchanting Santa Cruz de Tenerife, providing a rich city experience for travellers seeking to enjoy the area's vibrant history and scenic beauty.

  • Colchagua Campo y Vino: Immerse yourself in the luxury and relaxation of Colchagua Campo y Vino. This attraction offers memorable excursions through picturesque vineyards and lush landscapes, providing a taste of local wine culture and stunning views.
  • Hacienda El Huique: Located 13km from Santa Cruz, Hacienda El Huique is a historic building that showcases the rich cultural heritage of the region. Explore the architecture and learn about its significance in Chile’s history, all while enjoying the tranquil surroundings.
  • Plaza de Armas: Situated within Santa Cruz, Plaza de Armas is a vibrant city square that reflects the local culture. Stroll through the lively area, admire the architecture, and soak in the atmosphere of community life.

Best time to go to Santa Cruz

The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. January is its hottest month on average. At this time, visitor numbers are slightly high and weather is sunny with no rain. July is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January72.5°F (22.5°C)No RainSunnySlightly HighAverage
February71.6°F (22.0°C)No RainSunnySlightly HighAverage
March68.4°F (20.2°C)No RainSunnySlightly HighSlightly Low
April61.5°F (16.4°C)No RainSunnyAverageSlightly High
May55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
June49.6°F (9.8°C)Light RainMostly SunnyAverageSlightly High
July47.5°F (8.6°C)Light RainMostly SunnyAverageAverage
August50.0°F (10.0°C)Light RainMostly SunnyAverageAverage
September53.2°F (11.8°C)Light RainMostly SunnyAverageAverage
October57.9°F (14.4°C)No RainSunnySlightly LowAverage
November64.6°F (18.1°C)No RainSunnySlightly LowSlightly Low
December69.3°F (20.7°C)No RainSunnyAverageSlightly Low

The nearest major airports for your trip to Santa Cruz

Reaching Santa Cruz in the O'Higgins Region of Chile is convenient via Santiago's Arturo Merino Benitez Airport (SCL), situated 148km away. Notable hotels near the airport include The Singular Santiago, a luxurious 5-star hotel located 14km from SCL, offering 24-hour airport shuttle services. NH Ciudad de Santiago, a 4.5-star hotel 16km from the airport, provides on-request shuttles and transfers. Another excellent option is the Luciano K Hotel, also 16km away, featuring various transportation services. These accommodations ensure easy access to the airport, making your travel experience smooth and enjoyable.

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Based on our traveler data, Santa Cruz Plaza is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Other good choices for your trip include Hotel Vendimia Parador and Hotel Cava Colchagua. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best vacation home rentals that Santa Cruz has to offer?
Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly hotel in Santa Cruz?
Based on our traveler reviews, Hostal Gomero is a top choice for a less expensive stay. Other choices to stay on the cheap include Casa Suiza - Hostel and Hostal Cepa Noble. View all budget hotels in Santa Cruz.
What's the best hotel for families in Santa Cruz?
Santa Cruz Plaza is a hotel with an outdoor pool and a free kids' club, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.
What's the best pet-friendly place to stay in Santa Cruz?
Hotel Vendimia Parador is a top hotel for people traveling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet's trip include Hotel Hoja de Parra and El Refugio de Santa Cruz. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury hotel in Santa Cruz?
Vibo Wine Lodge is a luxury lodge with a winery and private balconies, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Hotel Vendimia Parador is a top hotel with an indoor pool, an outdoor pool, and free WiFi. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Santa Cruz Plaza is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, a free kid's club, and a bar. Treat yourself to a facial, body scrub, or hydrotherapy at the onsite spa. Other popular spa hotels in Santa Cruz include Hotel Cava Colchagua and Hostal Vida 2000. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the wineries, local tours, and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 32 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Wine tasting is a great activity, and Bodega Viña Viu Manent is one place to visit. A couple of additional sights to add to your agenda are Casino Colchagua and Colchagua Campo y Vino. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually January and February with an average temp of 70°F, while the coldest months are July and August with an average of 50°F. Average annual precipitation for Santa Cruz is 29 inches.

Explore a world of travel with Expedia