A vineyard with rows of grapevines.

Luxury Hotels in Santa Cruz, O'Higgins Region

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Check availability on Santa Cruz Luxury Hotels

Tonight
Oct 3 - Oct 4
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Oct 4 - Oct 5
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Oct 9 - Oct 11
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Oct 16 - Oct 18

Our top choices for Santa Cruz luxury hotels

A modern bedroom with a large bed, a small table, and a chair. It features a large window with a view of mountains and a lake.
A room with a large window, a chair with a patterned upholstery, a desk with a lamp, and a view of a natural landscape.
A room with a sofa, a table with a bottle and glasses, a large window with a view of trees and hills, and a wall with a blue abstract painting.
A modern bedroom with a large bed, a desk, and a chair, featuring a mountain view through floor-to-ceiling windows.

1. Vik Chile

Vik Chile
San Vicente
  • Relax amid wine country elegance at this San Vicente luxury hotel with 2 restaurants and a winery onsite.
P48,121
P48,121 total
Oct 4 - Oct 5
Vik Chile
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Top Santa Cruz Hotel Reviews

TerraViña

TerraViña

10/10 Excellent
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."
andy 2-night trip
Posted 2 months ago
TerraViña

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz vacation?
During your visit, you might want to enjoy the tours which Santa Cruz is known for.
What's the best high-end place to stay in Santa Cruz?
Vibo Wine Lodge is a luxury lodge with a winery and private balconies, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Santa Cruz?
Planning for the weather is an important factor for making your trip to Santa Cruz a success, especially when you're splurging. The hottest months are usually January and February with an average temp of 70°F, while the coldest months are July and August with an average of 50°F. Average annual precipitation for Santa Cruz is 29 inches.
What's there to see and do in Santa Cruz?
Experience all that Santa Cruz has to offer when you visit Casino Colchagua, Colchagua Campo y Vino, and Lapostolle Clos Apalta Winery. If you have some spare time during your trip, you might want to check out Millahue Valley and Museo de Colchagua.