Santa Cruz Trips (flight + hotel)

Photo by Vivian Rennó

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Top hotels in Santa Cruz

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is P6,167 per night from Aug 3 to Aug 4
P6,167
P6,167 total
Aug 3 - Aug 4
8.6/10 Excellent! (313 reviews)
"The hotel truly shines with its exceptional cleanliness and a refined design that takes inspiration from the Chilean countryside"

Reviewed on Jun 6, 2025

Santa Cruz Plaza
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is P5,139 per night from Aug 25 to Aug 26
P5,139
P5,139 total
Aug 25 - Aug 26
9.4/10 Exceptional! (76 reviews)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service."

Reviewed on Mar 24, 2025

Hotel Vendimia Parador
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
9/10 Wonderful! (96 reviews)
"Nice stay"

Reviewed on Apr 13, 2025

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La Perla Hotel
See all 52 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Lapostolle Clos Apalta Winery

You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Lapostolle Clos Apalta Winery

What to do in Santa Cruz

Viña Montes

Colchagua Valley Experience

P44,224
per adult
Colchagua Valley Experience
CLOS APALTA CELLAR

Clos Apalta and VIK Winery Private Experience with Lunch

P30,900
per adult
Clos Apalta and VIK Winery Private Experience with Lunch
Viu Manent tour

Viu Manent and Montes Winery, Colchagua Valley from semi-private

P15,875
per adult
Viu Manent and Montes Winery, Colchagua Valley from semi-private
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You can grab a vacation package to this destination on Expedia. However, how much your vacation to Santa Cruz costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Cruz?
You can usually find reduced prices and better availability in May, July and September. Browse our cheap Santa Cruz vacation packages and you could get some great off-season discounts.
How many days is enough for Santa Cruz?
You can see all the top attractions in Santa Cruz within a few days, including the must-see Museo de Colchagua. If you're looking for a longer Santa Cruz vacation, check out what sort of excursions and activities are available close by.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz has all the ingredients you need for an awesome getaway — history, culture and festivals are just the start. Whether you'd like to check out attractions like Plaza de Armas and Museo de Colchagua, or venture off the beaten track, there's plenty to experience on your Santa Cruz vacation.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then add some filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Santa Cruz package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Cruz escape underway.
Is it cheaper to book a Santa Cruz vacation as a package?
You can enjoy significant savings on your Santa Cruz getaway by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Cruz?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for an impromptu Santa Cruz trip.
How to plan a trip to Santa Cruz?

  1. Choose when to get away: Check your schedule and pack your bags. Your favorite season and the available activities will also help you decide when to vacation in Santa Cruz.
  2. Figure out your budget: Make sure you have enough money to pay for everything from food and transportation to airfares and activities. Your accommodations will probably be the largest expense during your trip to Santa Cruz.
  3. Work out your trip length: Consider how much time you'd like to spend discovering Santa Cruz. Plan your itinerary so you can get to all the activities and attractions you're interested in at a leisurely pace.
  4. Combine your accommodations and airfare: Once you've nailed down your trip dates and duration, book the perfect Santa Cruz vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.