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Santa Cruz Hotels

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Check prices for these dates

Tonight
Sep 28 - Sep 29
Tomorrow
Sep 29 - Sep 30
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

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Our top choices for Santa Cruz hotels

A modern hotel room with a bed, a TV, a wardrobe, and a bathroom.
A modern bathroom with a freestanding bathtub, a wooden bench, and a view of a cityscape through a large window.
A modern interior with a bar area, seating, and a counter.
A modern kitchen with a granite island, wooden cabinets, and a backsplash with glass tiles.

1. Blues Suites Laureles

Blues Suites Laureles
Laureles
United States
Silver
P3,024
P3,024 total
Sep 29 - Sep 30
Blues Suites Laureles
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.
A modern hotel room with a large bed, a cityscape mural on the wall, a wooden headboard, and a walk-in closet.
A spacious indoor dining area with multiple tables and chairs, large windows offering city views, and visible air ducts on the ceiling.
A casino with multiple slot machines and chairs arranged in rows.

2. Hotel Dorado La 70

Hotel Dorado La 70
Laureles
United States
Gregson
P4,518
P4,518 total
Oct 1 - Oct 2
Hotel Dorado La 70
A pathway leading to a building with a modern design, surrounded by lush greenery and trees.
A wooden desk with a shelf unit beside it, a door, and a light switch on the wall.
A modern bedroom with a single bed, a window with a view of greenery, a built-in air conditioning unit, and a door with a handle.
A modern bathroom with a glass-enclosed shower, a white toilet, and a wooden vanity.

3. Hotel centro logistico del norte

Hotel centro logistico del norte
Bello
P941
P1,716 total
Sep 30 - Oct 1
Hotel centro logistico del norte
A large, multi-story hotel with a classic architectural style, featuring a symmetrical facade and numerous windows.
A hotel room with two beds, a wooden headboard, and a nightstand with a lamp.
A hotel reception desk with a wooden ceiling and a sign that reads "HOTEL NUITIBARA".
A lobby with a large, ornate double door, a patterned floor, and a security camera on the ceiling.

4. Hotel Nutibara

Hotel Nutibara
La Candelaria
United States
Manny
P3,312
P3,312 total
Sep 29 - Sep 30
Hotel Nutibara
A woman in a black swimsuit sitting in a hot tub with a cityscape view through a glass railing.
A modern hotel room with a bed, a desk, a TV, and a balcony with a view.
An indoor cafe with brick walls, tables, chairs, and hanging plants.
A modern interior with a sofa, two armchairs, a coffee table, and a large potted plant.

5. Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group
La América
United States
Margarita
P2,907
P2,907 total
Sep 29 - Sep 30
Hotel Living 35 Suites by Growing Group
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.
A modern hotel room with a large bed, a sitting area with a table and chairs, a bathtub, and a balcony with a view of the city.
Gift shop
A multi-story hotel with a prominent 'EUTOPIO' sign, featuring a modern architectural design with a mix of brick and glass facades, and balconies with greenery.

6. Eutopiq Hotel

Eutopiq Hotel
Laureles
United States
Luis Alfonso
P4,615
P4,615 total
Sep 30 - Oct 1
Eutopiq Hotel
A hotel sign with a sun emblem, a modern glass building, and flags.
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.
A rooftop terrace with lounge chairs and a large umbrella, overlooking a cityscape at dusk.
A neatly arranged bedroom with a bed, bedside table, and a desk with a chair.

7. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
San Diego
United States
Domingo
P5,948
P5,948 total
Oct 3 - Oct 4
La Quinta by Wyndham Medellin
A modern lobby with leather chairs, a glass coffee table with flowers, a wine rack, and a large abstract painting on the wall.
A breakfast setting with toast, an omelet, a bowl of cereal, a glass of orange juice, and a fruit bowl.
An outdoor seating area with wicker furniture and planters.
A multi-story hotel with a modern design, featuring a mix of glass and stone facade, a visible entrance, and a small outdoor seating area.

8. Hotel Lleras 10

Hotel Lleras 10
El Poblado
United States
salvador
P2,304
P2,304 total
Sep 29 - Sep 30
Hotel Lleras 10
A hotel lobby with glass doors, a reception desk, and a chandelier.
A reception area with a dark wooden reception desk, a potted plant, and a colorful abstract painting on the wall.
A restaurant setting with a bar area in the background, featuring wine bottles and a TV screen.
A hotel entrance with a modern design, featuring a staircase leading to the lobby, a chandelier, and a sign indicating the hotel's name.

9. Hotel Egina Medellín

Hotel Egina Medellín
Laureles - Estadio
United States
Chad
P3,881
P3,881 total
Oct 14 - Oct 15
Hotel Egina Medellín
A breakfast buffet with a variety of food items, including fruits, pastries, and beverages, set up on a large table with stone bases.
A reception desk with a wooden finish, a black countertop, and a sign with handwritten text. There are three hanging pendant lights above the desk.
A modern hotel room with a large bed, a desk with a lamp, a chair, a bookshelf, and a large window with a city view.
A modern building with a geometric facade, multiple balconies with greenery, and a clear view of the surrounding cityscape.

10. Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
El Poblado
United States
Annier Marrero
P4,240
P4,240 total
Oct 1 - Oct 2
Hashtag 98 Hotel By Jalo
A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.
A hotel room with a bed, a small table with chairs, a coffee maker, and a view of the city through the window.
A multi-story building with a modern architectural design, featuring large windows and a brick facade.
A reception area with a brick wall, wooden tables, wicker pendant lights, and a reception desk.

11. Urbit Social Lofts

Urbit Social Lofts
Laureles
United States
Richard
P2,886
P2,886 total
Sep 29 - Sep 30
Urbit Social Lofts
A reception desk with a computer, potted plants, and a television screen.
An outdoor seating area with tables and chairs, a covered roof, and a view of parked cars and buildings in the background.
A modern living room with a sofa, two chairs, a small table, and a potted plant.
A modern elevator with a digital display, a reception area with a sofa and potted plants, and a wall-mounted clock.

12. Hotel Sauces Del Estadio

Hotel Sauces Del Estadio
Laureles - Estadio
United States
luz
P4,062
P4,062 total
Sep 29 - Sep 30
Hotel Sauces Del Estadio
A buffet table with various food items, including fruits, cheeses, and meats, along with juice and milk dispensers.
A modern hotel lobby with a glass railing, seating area, and a view of the street outside.
A hotel reception desk with a wooden finish, a modern logo, and informational brochures.
A hotel entrance with a sign reading 'HOTEL POBLADO BOUTIQUE.'

13. Hotel Poblado Boutique

Hotel Poblado Boutique
El Poblado
United States
Jacqueline
P1,715
P1,715 total
Oct 2 - Oct 3
Hotel Poblado Boutique
An outdoor seating area with potted plants and tables, a sign for a hotel, and a market in the background.
A hotel room with a bed, a desk, and a chair.
A staircase with a metal railing, a potted plant, and a vending machine with beverages.
A gym with exercise equipment, a treadmill, and a view of buildings through large windows.

14. Hotel Provenza Garden

Hotel Provenza Garden
El Poblado
United States
Alexander
P2,186
P2,186 total
Oct 2 - Oct 3
Hotel Provenza Garden
A modern hotel lobby with a reception desk, seating areas, and a staircase.
A modern staircase with glass railings and a view of the outside.
A modern living room with a black sofa, a glass coffee table, and a decorative mirror on the wall.
A buffet table with various food items and a decorative centerpiece.

15. Hotel El Portón de San Joaquín

Hotel El Portón de San Joaquín
Laureles
United States
Ryan
P3,737
P3,737 total
Sep 29 - Sep 30
Hotel El Portón de San Joaquín
A tall building with a modern design, featuring large windows and a sign that reads "SPRING SELECT EST 2025".
A restaurant with booths, tables, and chairs, featuring a modern design with plants and pendant lighting.
A bar area with shelves of wine bottles and glasses, decorated with green foliage.
A woman standing by a spa tub with a window and plants in the background.

16. Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
Laureles
United States
Norberto
P2,679
P2,679 total
Sep 30 - Oct 1
Hotel Ryo 74B Suites by Growing Group
A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.
A modern interior with a blue sofa, a hanging chair, a vending machine, and a refrigerator stocked with beverages.
A brick building with a sign reading "ibis budget."
A modern reception area with a black counter, a digital display, and a wall decorated with food and drink illustrations.

17. ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
Itagüí
United States
Heroll
P2,703
P2,703 total
Oct 2 - Oct 3
ibis budget Medellín Itagüí Metro
A modern kitchen with a central island, bar stools, a hanging chair, and a large window with a view.
A modern bedroom with a hanging chair, a bed, and two pendant lights.
A modern kitchen with built-in appliances, a large potted plant, and a bar stool.
A bar area with a counter labeled "Marshall," a person preparing a drink, and shelves with glasses and bottles.

18. Indie Universe Creative Hotel

Indie Universe Creative Hotel
Laureles
United States
Stanislav
P2,913
P2,913 total
Sep 29 - Sep 30
Indie Universe Creative Hotel
A modern bedroom with a bed, bedside table, lamp, and a view of the city through a window.
A modern interior with a curved wall, a staircase, and a seating area.
A modern building with large windows and a sign for "MOLINOS PLAZA".
A modern restaurant with tables and chairs, a kitchen area, and large windows.

19. Hotel Molinos by Growing Group

Hotel Molinos by Growing Group
Belen
United States
miki vimari
P2,632
P2,632 total
Oct 29 - Oct 30
Hotel Molinos by Growing Group
A modern interior with a large abstract painting on the wall, a glass railing, and a staircase with hanging plants.
A reception desk with a sign reading "HOTEL CENTRAL PLAZA," surrounded by hanging plants and a Coca-Cola refrigerator.
A modern hotel building with a sign reading "HOTEL CENTRAL PLAZA".
A spacious indoor area with multiple tables and chairs, large windows, and potted plants.

20. Hotel Central Plaza Medellin

Hotel Central Plaza Medellin
Itagüí
United States
William
P2,477
P2,477 total
Sep 29 - Sep 30
Hotel Central Plaza Medellin
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Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"Excelente"
Desayra 4-night trip
Posted 3 hours ago
Calle Flora Hotel by Jalo
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

10/10 Excellent
"Todo perfecto"
Giwoong 4-night trip
Posted 6 hours ago
Novotel Medellín El Tesoro
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

10/10 Excellent
"Great team, the service provided at the lobby, restaurant and room service was impeccable."
Juan 6-night trip
Posted 7 hours ago
Hashtag 98 Hotel By Jalo
NH Collection Medellín Royal

NH Collection Medellín Royal

10/10 Excellent
"This was our second time staying at the NH Collection Hotel, and once again, everything was wonderful. The hotel is lovely inside and out, and the location is absolutely perfect - only 2 blocks from the huge Santa Fe Shopping Mall. Our room and bathroom were very comfortable and spotless, and the housekeeping staff was extremely helpful. The breakfast was excellent every morning, as was the restaurant staff. We particularly appreciated Daisy and Diego keeping our coffee cups filled every morning. We also had dinner at the restaurant on the evening of our arrival, and both the food and the service were excellent. The thing that made our stay most enjoyable was the attention given by the staff. Upon getting out of the taxi, everyone at the hotel greeted us with a cheerful "Welcome Back!" Jorge, the bellman, was eager to grab our bags and take them to our room and make sure we were happy with our accommodations. Jose and Indira at the front desk were so friendly and helpful with every request we made! We so much enjoyed playing the piano in the lobby. We also very much appreciate the bellman, Miguel, helping us with a restaurant reservation, and it's so nice that Ricardo, the hotel manager, frequently walks through the hotel, warmly greeting guests. This hotel holds a very special place in our hearts, and we give it our highest recommendation!"
Lee Ann 6-night trip
Posted 21 hours ago
NH Collection Medellín Royal
Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"Las atenciones son expectaculares"
manuel Aurelio 3-night trip
Posted 1 day ago
Hotel San Fernando Plaza
Laureles Selection Suites

Laureles Selection Suites

10/10 Excellent
"A+"
Andrés Javier Rodríguez 4-night trip
Posted 2 days ago
Laureles Selection Suites
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Es la primera vez que visitamos Medellín , y tuvimos el placer de poder hospedarnos en el hotel y fue una experiencia inolvidable gracias por todo …."
Carlos Alberto 6-night trip
Posted 2 days ago
Dann Carlton Medellin Hotel
Hotel Dorado La 70

Hotel Dorado La 70

10/10 Excellent
"D show"
Luz Elena Montes 6-night trip
Posted 4 days ago
Hotel Dorado La 70
Medellin Marriott Hotel

Medellin Marriott Hotel

10/10 Excellent
"Excellent breakfast"
Omar Carmelo 7-night trip
Posted 6 days ago
Medellin Marriott Hotel

More cheap stays in Santa Cruz

Hotel Casa Malibú

Hotel Casa Malibú

Calle 32F 66 c 57 Medellín Medellin
P1,170
P1,170 total
Sep 29 - Sep 30
4.8/10 (3 reviews)
Hotel Casa Malibú
Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
P1,682
P1,682 total
Sep 29 - Sep 30
8.4/10 Very Good! (165 reviews)
Hostal Lleras Calle 8 - Hostel
Hotel Ofix - Laureles

Hotel Ofix - Laureles

79-86 Calle 44 Medellín
P2,084
P2,084 total
Sep 29 - Sep 30
8.4/10 Very Good! (94 reviews)
Hotel Ofix - Laureles
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
P2,520
P2,520 total
Oct 5 - Oct 6
9.2/10 Wonderful! (97 reviews)
Autenthico Sajonia Hotel Aeropuerto
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
P3,726
P3,726 total
Sep 30 - Oct 1
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
P5,124
P5,124 total
Oct 14 - Oct 15
9.2/10 Wonderful! (214 reviews)
Masaya Medellin

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 6.2 mi (10 km) from the heart of Santa Cruz, Calle Flora Hotel by Jalo is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Visitors are sure to enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 4 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What are the top places to visit in Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Arvi Park, and Antioquia Museum. You'll also find Botero Plaza and Atanasio Giradot Stadium in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Head over to Andalucía MetroCable Station for metro transit. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually August and July with an average temp of 66°F, while the coldest months are December and January with an average of 64°F. The rainiest months in Santa Cruz are May, April, October, and November, with each month seeing an average of 16 inches of rainfall.

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