Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
May 29 - May 31
In two months
Jul 10 - Jul 12
In three months
Aug 7 - Aug 9
In four months
Sep 4 - Sep 6

Our top choices for Santa Cruz vacation rentals

1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is P5,858
P5,858 total
Jun 4 - Jun 5
Shabbat Hotel Boutique
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very Good, (53 reviews)
"I liked everything, surrounded by incredible nature green hills, river and the wild sound."
United States
Alberto
The price is P2,690
P3,667 total
May 18 - May 19
PORTANOVA SUITES by ADVENTU
Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
The price is P4,431
P4,431 total
May 17 - May 18
Mali Experience
Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is P2,857
P7,091 total
May 17 - May 18
Almaia 17
Indoor pool

Casa Los Curazaos

Casa Los Curazaos
3.5 star property
Rionegro
8.0 out of 10, Very Good, (1 review)
"Hermosa cabaña, a tan solo 1km de la via que conduce de LLanogrande a la Ceja. Sobria, bien decorada, con todo lo necesario para una corta estadia. "
Mexico
CARLOS
The price is P8,322
P8,322 total
May 18 - May 19
Casa Los Curazaos
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Increíble view.. comfortable clean!! "
United States
Hector
The price is P3,508
P4,287 total
May 28 - May 29
Skyline Ecoliving
Mountain view

Sky View Glamping

Sky View Glamping
2.0 star property
Girardota
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is P7,327
P7,327 total
May 18 - May 19
Sky View Glamping
Room

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
The price is P5,129
P5,129 total
May 18 - May 19
Onirico Luxury
Front of property

Casa Hotel Fiba Magueza

Casa Hotel Fiba Magueza
4.5 star property
Guarne
The price is P3,012
P4,152 total
Jun 1 - Jun 2
Casa Hotel Fiba Magueza
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is P5,699
P7,164 total
May 16 - May 17
Candelaria Campestre
Restaurant

Hotel Distrito 70 Living

Hotel Distrito 70 Living
3.0 star property
Laureles - Estadio
The price is P3,617
P3,617 total
May 27 - May 28
Hotel Distrito 70 Living
Front of property

Hotel Moore 45

Hotel Moore 45
2.5 star property
Buenos Aires
8.8 out of 10, Excellent, (3 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
The price is P1,808
P1,808 total
May 24 - May 25
Hotel Moore 45
View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is P4,308
P4,308 total
May 16 - May 17
Travelers Rio Verde Living Suites
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (61 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is P6,102
P6,102 total
May 16 - May 17
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Front of property

Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (5 reviews)
"Hotel nuevo, excelentes instalaciones, limpieza impecable, solo un detalle, solicité habitación para 4 personas y tenía una cama queen y sofá cama, solo que el sofá cama era algo incómodo para descanzar, de lo demás estuvo excelente."
Mexico
Moisés
The price is P3,046
P4,674 total
Jun 15 - Jun 16
Nomadic Boutique Living and Experience Center
1 bedroom

Olive Country Living - 205

Olive Country Living - 205
2.0 star property
Envigado
The price is P7,372
P12,463 total
May 21 - May 22
Olive Country Living - 205
1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (273 reviews)
"excellent . great people . great menu and great location"
United States
Gilberto
The price is P3,834
P3,834 total
May 23 - May 24
Portal del Rodeo ApartaHotel - Arkadia Mall
Premium bedding, down comforters, minibar, in-room safe

Devú

Devú
5.0 star property
El Poblado
10.0 out of 10, Exceptional, (5 reviews)
"Our week-long stay at Hotel Devú was an overall fantastic experience, highlighted by an incredibly warm and professional welcome that set the tone for the entire trip. The rooms were consistently spotless and well-maintained, and the customer service across the board was a perfect 5 out of 5. The only minor drawback we encountered was that room service comes with an additional fee, which was the only thing we didn't quite like. However, everything else was so exceptional that we would still...
Canada
Kejeevan
The price is P16,812
P16,812 total
May 24 - May 25
Devú
Exterior

Manila Apartaestudios

Manila Apartaestudios
3.0 star property
El Poblado
The price is P4,030
P4,844 total
May 27 - May 28
Manila Apartaestudios
Mountain view

Grand By Jalo

Grand By Jalo
4.5 star property
El Poblado
9.0 out of 10, Wonderful, (13 reviews)
"It was clean and a beautiful place to stay in "
United States
Judith
The price is P5,890
P5,890 total
May 21 - May 22
Grand By Jalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Very nice stay as always at a Dann Carlton property. Comfortable bed. Linens could use updated. Water pressure excellent and plenty of hot water. Restaurants are good 43 Street is excellent. Breakfast buffet was perfect for me. Lots of good fruit. Pool is nice and big and clean with a lot of loungers and tables with umbrellas. Location is perfect. Lots within walking distance. I highly recommend."
Andrew 4-night trip
Posted 1 hour ago
Dann Carlton Medellin Hotel

Find out more about Santa Cruz

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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxury Home In Las Lomas: You might want to consider this Santa Cruz vacation home rental for your stay. It is equipped with an outdoor pool, air-conditioning, and free WiFi to help you feel comfortable during your stay. It has 6 bedrooms as well as a kitchen with a full-sized fridge, a microwave, and a coffee maker, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find University of Antioquia and Arvi Park.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.