Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Apr 10 - Apr 12
In two months
May 22 - May 24
In three months
Jun 19 - Jun 21
In four months
Jul 17 - Jul 19

Our top choices for Santa Cruz vacation rentals

1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is P5,394
P5,394 total
Apr 12 - Apr 13
Shabbat Hotel Boutique
Minibar, individually decorated, individually furnished, free WiFi

Wasikuna cabañas rurales tipo glamping

Wasikuna cabañas rurales tipo glamping
3.0 star property
Guarne
10.0 out of 10, Exceptional, (4 reviews)
"Nice place "
United States
GERARDO
The price is P6,773
P6,773 total
Mar 30 - Mar 31
Wasikuna cabañas rurales tipo glamping
Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
The price is P4,492
P4,492 total
Mar 30 - Mar 31
Mali Experience
Interior

Casagrande

Casagrande
2.0 star property
Rionegro
The price is P3,301
P3,301 total
Mar 30 - Mar 31
Casagrande
Mountain view

Sky View Glamping

Sky View Glamping
2.0 star property
Girardota
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is P6,602
P6,602 total
Mar 30 - Mar 31
Sky View Glamping
Room

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
The price is P5,199
P5,199 total
Apr 29 - Apr 30
Onirico Luxury
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (41 reviews)
"Super impressive mountain view directly visible as soon as you open your eyes in the morning. "
United States
Antranik
The price is P3,556
P4,345 total
Apr 9 - Apr 10
Skyline Ecoliving
Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is P8,252
P25,086 total
Mar 30 - Mar 31
Almaia 17
Desk, laptop workspace, blackout drapes, soundproofing

Edificio Cielo Verde

Edificio Cielo Verde
3.0 star property
Rionegro
The price is P8,582
P10,232 total
Mar 30 - Mar 31
Edificio Cielo Verde
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very Good, (50 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
The price is P2,727
P3,717 total
Mar 30 - Mar 31
PORTANOVA SUITES by ADVENTU
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is P5,776
P7,262 total
Apr 6 - Apr 7
Candelaria Campestre
View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is P4,723
P4,723 total
Mar 30 - Mar 31
Travelers Rio Verde Living Suites
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (60 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is P5,995
P5,995 total
Apr 6 - Apr 7
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Premium bedding, down comforters, minibar, free WiFi

Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.0 out of 10, Very Good, (1 review)
The price is P1,734
P1,734 total
Apr 5 - Apr 6
Hotel Moore 45
15 outdoor pools

Llano Grande

Llano Grande
3.5 star property
Rionegro
The price is P479,876
P485,932 total
Mar 30 - Mar 31
Llano Grande
Front of property

Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
3.5 star property
El Poblado
9.6 out of 10, Exceptional, (4 reviews)
"Hotel nuevo, excelentes instalaciones, limpieza impecable, solo un detalle, solicité habitación para 4 personas y tenía una cama queen y sofá cama, solo que el sofá cama era algo incómodo para descanzar, de lo demás estuvo excelente."
Mexico
Moisés
The price is P4,601
P6,252 total
Apr 5 - Apr 6
Nomadic Boutique Living and Experience Center
Room

hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
The price is P1,404
P1,404 total
Apr 6 - Apr 7
hotel civitas medellin
Outdoor dining

Onirico Refugio

Onirico Refugio
2.0 star property
Medellín
The price is P5,199
P5,199 total
Mar 30 - Mar 31
Onirico Refugio
1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (270 reviews)
"the staff was very friendly good food and the room is so nice highly recomended"
United States
Astrid
The price is P3,886
P3,886 total
Apr 5 - Apr 6
Portal del Rodeo ApartaHotel - Arkadia Mall
Outdoor pool

Casa Terracina By HOUSY HOST

Casa Terracina By HOUSY HOST
3.5 star property
Envigado
8.0 out of 10, Very Good, (3 reviews)
"The property was ok. Beautiful house but a bit run down. Not enough utensils in the kitchen for cooking and eating. The swimming pool is amazing, clean and heated. The dry sauna works well. The wet sauna does not work and the jacuzzi is not operable. The garden is one of the best features, it felt like paradise. It is a great place for a quiet family stay. Housy Host's best asset is Wilson, the person that takes care of the space while you are there. He is very attentive, while giving you all...
Mexico
Maria
The price is P17,129
P20,763 total
Apr 29 - Apr 30
Casa Terracina By HOUSY HOST
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"I had a great time"
Abdelhady 1-night trip
Posted 5 hours ago
Hotel San Fernando Plaza

Find out more about Santa Cruz

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Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find Parque Fabricato Shopping Center and University of Antioquia.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.