Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Feb 27 - Mar 1
In two months
Apr 10 - Apr 12
In three months
May 8 - May 10
In four months
Jun 5 - Jun 7

Our top choices for Santa Cruz vacation rentals

Private spa tub

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (658 reviews)
"This hotel was amazing. The staff was great and my overall stay was 10/10"
United States
Alvin Ammaad
The price is P6,377
P6,377 total
Feb 24 - Feb 25
Haven, A Design Hotel
Rooftop terrace

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1,468 reviews)
"Great staff, pool and amenities!"
United States
alba
The price is P9,478
P9,478 total
Mar 8 - Mar 9
York Medellin, Curio Collection by Hilton
View from room

Wake Living

Wake Living
4.0 star property
El Poblado
8.8 out of 10, Excellent, (173 reviews)
"Great location best views"
United States
William
Wake Living
Premium bedding, down comforters, Select Comfort beds, minibar

Royal Living Poblado

Royal Living Poblado
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (59 reviews)
"Comfortable and safe stay"
United States
Julian
The price is P2,684
P2,684 total
Feb 15 - Feb 16
Royal Living Poblado
Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Espectacular apartamento y el sitio es muy bueno"
Colombia
Giovanni
The price is P3,798
P3,798 total
Feb 16 - Feb 17
Mali Experience
Outdoor pool

Energy 801 One Bedroom Executive

Energy 801 One Bedroom Executive
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (27 reviews)
"Beautiful property. I definitely recommend "
United States
Alexander
Energy 801 One Bedroom Executive
Reception

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,129 reviews)
"Clean room, wonderful staff and great location!!!"
United States
Marleny
The price is P5,503
P5,503 total
Feb 16 - Feb 17
Sites Hotel
Front of property

Seissta Medellin

Seissta Medellin
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (221 reviews)
"Excellent staff outstanding service the best "
United States
Santiago
The price is P6,284
P6,284 total
Mar 14 - Mar 15
Seissta Medellin
View from property

Living by Armoniko

Living by Armoniko
4.0 star property
Laureles
9.4 out of 10, Exceptional, (61 reviews)
"Very good excellent service room clean and service is the best "
United States
Juan
Living by Armoniko
Property entrance

Provenza Lofts

Provenza Lofts
3.0 star property
El Poblado
8.2 out of 10, Very Good, (148 reviews)
"Nice and staff was great with communication "
United States
Bryant
The price is P4,688
P4,688 total
Feb 15 - Feb 16
Provenza Lofts
Balcony view

Apartamentos Class Suites by HOUSY HOST

Apartamentos Class Suites by HOUSY HOST
3.0 star property
El Poblado
7.8 out of 10, Good, (26 reviews)
"Very nice"
United States
Levon
Apartamentos Class Suites by HOUSY HOST
Minibar, individually decorated, individually furnished, free WiFi

Wasikuna cabañas rurales tipo glamping

Wasikuna cabañas rurales tipo glamping
3.0 star property
Guarne
10.0 out of 10, Exceptional, (4 reviews)
"Nice place "
United States
GERARDO
Wasikuna cabañas rurales tipo glamping
Reception

Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.2 out of 10, Wonderful, (35 reviews)
"Great location."
United States
Nekitta
The price is P2,409
P4,282 total
Feb 18 - Feb 19
Metropolitan Living by HOUSY
In-room safe, laptop workspace, blackout drapes, iron/ironing board

GRES Apartamentos

GRES Apartamentos
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (22 reviews)
"Great place to stay not too far from Provenza "
United States
Juan
The price is P4,608
P4,608 total
Mar 5 - Mar 6
GRES Apartamentos
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (57 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Front of property

Hotel 10-36

Hotel 10-36
2.5 star property
El Poblado
7.8 out of 10, Good, (12 reviews)
"Place was great, staff was even better. Very safe an clean, excellent location and a must visit "
United States
Kevin
The price is P4,504
P4,504 total
Feb 26 - Feb 27
Hotel 10-36
1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
Shabbat Hotel Boutique
Reception

Luxury Apto 2 Bd-2 AC in Aguacatala

Luxury Apto 2 Bd-2 AC in Aguacatala
2.0 star property
El Poblado
10.0 out of 10, Exceptional, (1 review)
"La habitacion excelente, cumplimiento igualmente, la ubicacion cerca a centros comerciales."
Colombia
Oscar
The price is P6,584
P8,925 total
Feb 16 - Feb 17
Luxury Apto 2 Bd-2 AC in Aguacatala
Living area

H10 Provenza

H10 Provenza
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (3 reviews)
"El partamento estaba impecable , tuve un problema con el aire acondicionado pero la estancia fue cómoda y placentera."
Mexico
Oscar
The price is P6,290
P8,203 total
Feb 16 - Feb 17
H10 Provenza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

10/10 Excellent
"La camarera siempre nos tenia la avotacion limpia.la atención en el hotel es de 5 estrellas.uno de los 2 server de la mañana son muy hospitalario.el rooftop tenia muy buen ambiente."
Jadiam 5-night trip
Posted 23 hours ago
Hashtag 98 Hotel By Jalo

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

La Gracia Hotel & Spa: Visitors like this Santa Cruz vacation home rental. It offers a terrace, a garden, and free WiFi to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find University of Antioquia and Arvi Park.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.