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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Jul 17 - Jul 19
In two months
Aug 28 - Aug 30
In three months
Sep 25 - Sep 27
In four months
Oct 23 - Oct 25

Our top choices for Santa Cruz vacation rentals

View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (476 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is P4,845
P4,845 total
Jul 5 - Jul 6
Travelers Rio Verde Living Suites
1 bedroom, premium bedding, down comforters, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (280 reviews)
"The best!"
United States
Samuel
The price is P3,850
P3,850 total
Jul 1 - Jul 2
Portal del Rodeo ApartaHotel - Arkadia Mall
Minibar, desk, laptop workspace, blackout drapes

Mali Experience

Mali Experience
3.0 star property
Rionegro
9.6 out of 10, Exceptional, (7 reviews)
"Perfect property ! Big enough. Big fridge, full kitchen; excellent bathroom and bed. The whole room is full little details and excellent design!"
United States
Jorge
The price is P4,822
P4,822 total
Jul 30 - Jul 31
Mali Experience
1 bedroom, premium bedding, down comforters, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is P6,374
P6,374 total
Jul 16 - Jul 17
Shabbat Hotel Boutique
Terrace/patio

Encanto Verde

Encanto Verde
2.5 star property
Marinilla
The price is P2,659
P3,394 total
Jul 7 - Jul 8
Encanto Verde
Outdoor dining

Hotel Boutique Almaia 17 Near the Airport

Hotel Boutique Almaia 17 Near the Airport
3.0 star property
Rionegro
The price is P1,908
P6,525 total
Jul 4 - Jul 5
Hotel Boutique Almaia 17 Near the Airport
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Increíble view.. comfortable clean!! "
United States
Hector
The price is P2,674
P3,522 total
Jul 6 - Jul 7
Skyline Ecoliving
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.2 out of 10, Very Good, (62 reviews)
"I liked everything, surrounded by incredible nature green hills, river and the wild sound."
United States
Alberto
The price is P3,100
P4,163 total
Jul 7 - Jul 8
PORTANOVA SUITES by ADVENTU
Premium bedding, down comforters, individually decorated

Ancestral Glamping

Ancestral Glamping
2.0 star property
Barbosa
The price is P8,684
P8,684 total
Jul 5 - Jul 6
Ancestral Glamping
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (64 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is P6,056
P6,056 total
Jul 30 - Jul 31
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Front of property

Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
4.0 star property
El Poblado
9.8 out of 10, Exceptional, (10 reviews)
"Good property and the area looks safe."
Canada
Josue
The price is P2,976
P3,419 total
Jul 2 - Jul 3
Nomadic Boutique Living and Experience Center
Restaurant

Edificio Helena

Edificio Helena
3.0 star property
Medellín
8.8 out of 10, Excellent, (64 reviews)
"Awesome breakfast, great location. Great host"
United States
James
The price is P2,590
P2,590 total
Jul 30 - Jul 31
Edificio Helena
Premium bedding, down comforters, minibar, free WiFi

Hotel Moore 45

Hotel Moore 45
2.5 star property
Buenos Aires
8.8 out of 10, Excellent, (3 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
Hotel Moore 45
Lobby

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (702 reviews)
"The reception staff were great hosts, the room was as advertised. A nice hotel and good location"
United States
Neil
The price is P5,533
P5,533 total
Jul 14 - Jul 15
Haven, A Design Hotel
Reception

Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.2 out of 10, Wonderful, (68 reviews)
"Staff was very polite, location was perfect… very close to amazing tourism spots! "
United States
Patricia
The price is P2,953
P4,299 total
Jul 7 - Jul 8
Metropolitan Living by HOUSY
Mountain view

Sky View Glamping

Sky View Glamping
2.0 star property
Girardota
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is P7,175
P7,175 total
Jul 1 - Jul 2
Sky View Glamping
Indoor pool

Casa Los Curazaos

Casa Los Curazaos
3.5 star property
Rionegro
8.0 out of 10, Very Good, (1 review)
"Hermosa cabaña, a tan solo 1km de la via que conduce de LLanogrande a la Ceja. Sobria, bien decorada, con todo lo necesario para una corta estadia. "
Mexico
CARLOS
The price is P9,932
P9,932 total
Jul 4 - Jul 5
Casa Los Curazaos
Free daily full breakfast

Laureles Guest House - LGH Hotel

Laureles Guest House - LGH Hotel
3.5 star property
Laureles
9.2 out of 10, Wonderful, (97 reviews)
"Excellent breakfast, good location "
United States
dickie
The price is P2,635
P2,635 total
Jul 1 - Jul 2
Laureles Guest House - LGH Hotel
Desk, laptop workspace, free WiFi

ONCE SUITES

ONCE SUITES
2.5 star property
Envigado
The price is P2,916
P2,916 total
Jul 9 - Jul 10
ONCE SUITES
Blackout drapes, free WiFi

A Estadia tranquila con vista al bosque

A Estadia tranquila con vista al bosque
2.5 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Todo como lo esperado, volvería."
Colombia
Gustavo Adolfo
The price is P3,915
P4,833 total
Jul 7 - Jul 8
A Estadia tranquila con vista al bosque
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"bueno , si no purdes dormir con ruido el hotel no es para ti"
laryanna 4-night trip
Posted 6 hours ago
Calle Flora Hotel by Jalo

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
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Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we offer vacation rentals close to popular attractions in Santa Cruz, or you can choose a more secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxury Home In Las Lomas: You might want to consider this Santa Cruz vacation home rental for your stay. It is equipped with an outdoor pool, air-conditioning, and free WiFi to help you feel comfortable during your stay. It has 6 bedrooms as well as a kitchen with a full-sized fridge, a microwave, and a coffee maker, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the larger area, you’ll find Parque Fabricato Shopping Center and University of Antioquia.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties where you can stay for a long or short time in Santa Cruz. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for families.