South Main
Houston
Visit South Main
Popular places to visit
NRG Stadium
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
George R. Brown Convention Center
During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the great live music and acclaimed art scene in this vibrant area.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and acclaimed theater scene in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and acclaimed art scene in this vibrant area.
Space Center Houston
Visit the heart of the American space industry in the control centre that put man on the moon.
Things to do
Space Center Houston Admission Ticket
NASA's Space Center Admission Plus Houston City Tour
Houston's Official City & Mural Tour!
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston Museum of Natural Science General Admission Ticket
Houston: Houston Botanic Garden Entry Ticket
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
They had us waiting for hours before we could check in they said the system was down and they did not give us any accommodations they were double booking rooms our room had no toilet paper. I will Never stay here again!
Reviewed on Feb 27, 2026
Hotel Zaza Houston Museum District
Amazing location. Amazing staff and even nicer rooms
Reviewed on Feb 24, 2026
Blossom Hotel Houston, Curio Collection by Hilton
Polite stuff, clean room, nice view,
Reviewed on Feb 27, 2026
The Royal Sonesta Houston Galleria
It was my first visit in Houston but I had a great time staying in this hotel ..Stuff is friendly specially Miss Martha the front desk who send me an early surprise gift inside my room despite my birthday still far away on March .☺️the food is great ❤️the hotel is very clean .and it’s convenient ...
Reviewed on Feb 26, 2026
The Whitehall Houston
Club Quarters Hotel Downtown, Houston
Staffing extremely nice and helpful!
Reviewed on Feb 27, 2026
Other neighbourhoods around South Main
Astrodome
If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Astrodome and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Greenway Plaza-Upper Kirby
Travelers come to Greenway Plaza-Upper Kirby for its abundant dining options, and you can see top attractions like Highland Village and Richmond Avenue while you're in town.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
