Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the lively festivals and acclaimed art scene in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed art scene and entertainment choices in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and acclaimed art scene in this vibrant area.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed theater scene and fascinating museums.
University of Houston
Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the great live music and lively festivals in this vibrant area.
Things to do
Houston's Official City & Mural Tour!
Houston Museum of Natural Sciences: Planetarium Ticket
Space Center Houston Admission Ticket
Houston Museum of Natural Science General Admission Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center
Houston Museum of Natural Science and Cockrell Butterfly Center
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Reviewed on Oct 4, 2025
Club Quarters Hotel Downtown, Houston
Reviewed on Oct 4, 2025
The Whitehall Houston
Reviewed on Oct 3, 2025
Hilton Houston Plaza/Medical Center
Reviewed on Oct 4, 2025
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Reviewed on Oct 3, 2025
Blossom Hotel Houston
Reviewed on Oct 3, 2025
Other neighbourhoods around South Main
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travelers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
Greater Third Ward
While you're in Greater Third Ward, take in top sights like TDECU Stadium or Eldorado Ballroom, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
