South Main

Houston

Photo by Hazem Abdul

Popular places to visit

Things to do


Top hotels in South Main

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive, Houston, TX
The price is P4,895 per night from Aug 4 to Aug 5
P4,895
P5,726 total
Aug 4 - Aug 5
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
7/10 Good! (1,131 reviews)
"Rim was clean and spacious will be back"

Reviewed on Jul 27, 2025

Wyndham Houston near NRG Park/Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
The price is P22,072 per night from Aug 13 to Aug 14
P22,072
P28,511 total
Aug 13 - Aug 14
includes taxes & fees
Stay at this 4.5-star luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (1,730 reviews)
"The welcome snack and wine were nice! Dinner was delicious."

Reviewed on Jul 30, 2025

Hotel Zaza Houston Museum District
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is P8,306 per night from Aug 14 to Aug 15
P8,306
P9,718 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,646 reviews)
"Everything perfect, just the check in is not so usual , they include and extra charge of 250 usd with the cost of the room for guaranteed the extra charges and I haven’t received the return yet."

Reviewed on Aug 1, 2025

The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
The price is P5,753 per night from Sep 1 to Sep 2
P5,753
P6,778 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,314 reviews)
"I enjoyed the balcony and the pool access. The room was so big. Wish i didnt have to pay for parking."

Reviewed on Aug 2, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
The price is P5,323 per night from Sep 1 to Sep 2
P5,323
P6,296 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,492 reviews)
"Nice and affordable"

Reviewed on Aug 2, 2025

Hilton Houston Plaza/Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
The price is P6,107 per night from Aug 5 to Aug 6
P6,107
P7,145 total
Aug 5 - Aug 6
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,559 reviews)
"Great location close to everything"

Reviewed on Jul 31, 2025

Club Quarters Hotel Downtown, Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

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Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
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The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

The Galleria
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Midtown

The restaurants and live music are just a few things visitors like about Midtown. Continental Club and Midtown Arts and Theater Center Houston are worthwhile spots to check out, and you can hop on the metro at McGowen Station or Ensemble/HCC Station to get around the larger area.

Midtown

South Main