South Main

Houston

A city skyline with modern buildings and a park with a lake.
A modern urban street with a metro train, buildings, and a clear blue sky.

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

P1,869
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston Museum of Natural Sciences: Planetarium Ticket

Houston Museum of Natural Sciences: Planetarium Ticket

P749
per adult
82% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center

Houston Museum of Natural Science: Butterfly Center Ticket

P936
per adult
100% of travellers recommend
Houston Museum of Natural Science: Butterfly Center Ticket
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

P750
per adult
74% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
The Official Houston City Tour

NASA's Space Center & Official Houston City Tour with tickets

P6,186
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
Houston: Museum of Natural Science General Admission Ticket

Houston: Museum of Natural Science General Admission Ticket

P1,563
per adult
98% of travellers recommend
Houston: Museum of Natural Science General Admission Ticket
See all activities in Houston

Top hotels in South Main

Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center

3.5 out of 5
8686 Kirby Drive Houston TX
The price is P6,139 per night from Oct 5 to Oct 6
P6,139
per night
Oct 5 - Oct 6
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful staff ...
7.2/10 Good! (1,417 reviews)
"It needs alot of remodeling its clean but it hs a weird smell maybe cuase its old."

Reviewed on Sep 30, 2026

Wyndham Houston at Reliant Park & Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
The price is P7,902 per night from Oct 22 to Oct 23
P7,902
per night
Oct 22 - Oct 23
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is P16,385 per night from Oct 4 to Oct 5
P16,385
per night
Oct 4 - Oct 5
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Hotel Zaza Houston Museum District
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
The price is P8,496 per night from Oct 20 to Oct 21
P8,496
per night
Oct 20 - Oct 21
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
The Whitehall Houston
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
The price is P5,639 per night from Oct 4 to Oct 5
P5,639
per night
Oct 4 - Oct 5
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
Club Quarters Hotel Downtown, Houston
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
The price is P6,208 per night from Oct 2 to Oct 3
P6,208
per night
Oct 2 - Oct 3
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
Hyatt Regency Houston West
See all 7,465 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
A sculpture garden with abstract art pieces in a city park.

Downtown Houston

Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A modern building with a covered outdoor area and a circular garden feature.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

South Main