South Main Hotels near Houston

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Top Trending Hotels Near South Main, Houston

Wyndham Houston near NRG Park/Medical Center
Lobby

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1171)
"Everyone was very pleasant, I will be returning."
The price is P5,757
P6,736 total
includes taxes & fees
Oct 3 - Oct 4
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1001)
"The rooms were clean, the beds were soft, the staff was friendly. The breakfast wasnt bad either. It was literally the best bang for our buck. "
The price is P3,611
P4,225 total
includes taxes & fees
Oct 22 - Oct 23
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
Gazebo

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (941)
"Walking distance to NRG Stadium "
The price is P5,292
P6,191 total
includes taxes & fees
Oct 14 - Oct 15
Wingate Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (799)
"The staff is great. The area is questionable due to homeless population."
The price is P4,303
P5,035 total
includes taxes & fees
Oct 13 - Oct 14
Candlewood Suites Houston Medical Center by IHG
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hyatt Regency Houston/Galleria

4.0 star property
9.0 out of 10, Wonderful, (1075)
" Good hotel"
The price is P9,653
P11,362 total
includes taxes & fees
Oct 23 - Oct 24
Hyatt Regency Houston/Galleria
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (2004)
"Great place to stay!"
The price is P8,083
P9,507 total
includes taxes & fees
Oct 3 - Oct 4
Hyatt Place Houston Medical Center
The Lancaster Hotel
Exterior

The Lancaster Hotel

4.0 star property
9.8 out of 10, Exceptional, (1001)
"Great place... lots of nice people and nice rooms."
The Lancaster Hotel
The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.6 out of 10, Excellent, (1768)
"Great staff nice rooms"
The price is P8,507
P9,954 total
includes taxes & fees
Oct 5 - Oct 6
The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.2 out of 10, Very Good, (2612)
"Great stay!!!"
The price is P7,351
P8,661 total
includes taxes & fees
Oct 31 - Nov 1
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Really enjoyed my stay. "
The price is P10,188
P12,099 total
includes taxes & fees
Oct 17 - Oct 18
Omni Houston Hotel
Hyatt House Houston Medical Center
Lobby

Hyatt House Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1121)
"Have stayed there many times"
The price is P8,083
P9,507 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt House Houston Medical Center
Hyatt Regency Houston West
Breakfast, lunch, brunch served; American cuisine, garden views

Hyatt Regency Houston West

3.5 star property
8.6 out of 10, Excellent, (1176)
"Great stay for work trips."
The price is P6,397
P7,484 total
includes taxes & fees
Oct 10 - Oct 11
Hyatt Regency Houston West
La Quinta Inn & Suites by Wyndham Houston Southwest
Exterior

La Quinta Inn & Suites by Wyndham Houston Southwest

3.0 star property
7.0 out of 10, Good, (1002)
"Great stay. "
The price is P3,954
P4,626 total
includes taxes & fees
Oct 5 - Oct 6
La Quinta Inn & Suites by Wyndham Houston Southwest
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (588)
"Staff was friendly, room was clean, and quiet area!"
The price is P6,746
P7,892 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express & Suites Houston – Downtown North by IHG
Haven Inn & Suites Downtown Houston
Premium bedding, desk, iron/ironing board, free WiFi

Haven Inn & Suites Downtown Houston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Was great stay."
Haven Inn & Suites Downtown Houston
Club Quarters Hotel Downtown, Houston
Lobby

Club Quarters Hotel Downtown, Houston

4.0 star property
8.4 out of 10, Very Good, (3726)
"Overall great property to stay at. "
The price is P6,228
P7,287 total
includes taxes & fees
Oct 3 - Oct 4
Club Quarters Hotel Downtown, Houston
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.4 out of 10, Very Good, (1285)
"Great hotel "
The price is P6,376
P7,460 total
includes taxes & fees
Oct 17 - Oct 18
The Royal Sonesta Houston Galleria
Sonesta ES Suites Houston Galleria
Lobby

Sonesta ES Suites Houston Galleria

3.0 star property
8.2 out of 10, Very Good, (1094)
"This hotel was great, lovely & convenience is a double plus! My family and I enjoyed our stay."
The price is P6,376
P7,460 total
includes taxes & fees
Oct 7 - Oct 8
Sonesta ES Suites Houston Galleria
Heights House Hotel - Houston Heights Downtown, an Ascend Collection Hotel
View from room

Heights House Hotel - Houston Heights Downtown, an Ascend Collection Hotel

3.0 star property
7.8 out of 10, Good, (1000)
"Loved the commons/patio area "
The price is P5,634
P6,592 total
includes taxes & fees
Oct 16 - Oct 17
Heights House Hotel - Houston Heights Downtown, an Ascend Collection Hotel
Moxy Houston Downtown
Front of property - evening/night

Moxy Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (598)
"Nice location in the city, close to the baseball stadium. "
The price is P6,746
P8,028 total
includes taxes & fees
Oct 5 - Oct 6
Moxy Houston Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a square or plaza, city views and a city

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston featuring a skyscraper and a city

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria

10/10 Excellent
"This was a last minute trip, and first time staying at this hotel. This was an amazing place. The staff were absolutely amazing. The rooms we very well kept up on. The pool area was really enjoyable. The free breakfast was great. It is also located near many unique shops and restaurants. Overall, very very happy, and look forward to visiting here again. "
George 4-night trip
Posted 3 days ago
Hyatt Place Houston/Galleria

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Candlewood Suites Houston Medical Center by IHG is the highest ranked property in South Main. This hotel offers free parking and in-room kitchens. Other top choices in the neighborhood include Quality Inn & Suites NRG Park - Medical Center and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.