South Main Hotels near Houston

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Our top choices for South Main hotels

Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG
2.5 star property
South Main
7.4 out of 10, Good, (835 reviews)
"This is a safe, friendly hotel close to MDA Cancer Center"
United States
Myra
The price is P5,571
P6,518 total
includes taxes & fees
Feb 18 - Feb 19
Candlewood Suites Houston Medical Center by IHG

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,002 reviews)
"Clean room, helpful staff and good location to hospital."
United States
George
The price is P6,009
P7,030 total
includes taxes & fees
Feb 19 - Feb 20
Comfort Suites Houston near Medical Center- NRG Stadium

Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center
2.5 star property
South Main
6.6 out of 10, (1,002 reviews)
"Room was clean, bed was comfortable, breakfast was good. Perfect place to stay for going to NRG Stadium as it’s an easy walk"
United Kingdom
Daniel
The price is P4,782
P5,594 total
includes taxes & fees
Feb 18 - Feb 19
Quality Inn & Suites NRG Park - Medical Center

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (1,000 reviews)
"Easy access to stadium "
United States
Richard
The price is P4,062
P4,752 total
includes taxes & fees
Feb 17 - Feb 18
Wingate Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,218 reviews)
"Front desk staff was very professional and kind."
United States
MARINA
The price is P5,803
P6,789 total
includes taxes & fees
Feb 17 - Feb 18
Wyndham Houston near NRG Park/Medical Center

Fairfield Inn & Suites Houston Intercontinental Airport

Fairfield Inn & Suites Houston Intercontinental Airport
3.0 star property
30.6 km from South Main
8.6 out of 10, Excellent, (1,002 reviews)
"Great place, nice room"
United States
Lester
The price is P4,989
P5,939 total
includes taxes & fees
Feb 22 - Feb 23
Fairfield Inn & Suites Houston Intercontinental Airport

Baymont by Wyndham Houston Hobby Airport

Baymont by Wyndham Houston Hobby Airport
2.5 star property
18.4 km from South Main
8.6 out of 10, Excellent, (895 reviews)
"Very clean !! every thing is new. breakfast also very good, we will comeback to stay again."
United States
LEI
The price is P3,699
P4,351 total
includes taxes & fees
Feb 23 - Feb 24
Baymont by Wyndham Houston Hobby Airport

Four Points by Sheraton Houston Intercontinental Airport

Four Points by Sheraton Houston Intercontinental Airport
3.0 star property
29.9 km from South Main
8.4 out of 10, Very Good, (1,007 reviews)
"The staff was friendly and the hotel was clean"
United States
Lisa
The price is P5,130
P6,002 total
includes taxes & fees
Feb 20 - Feb 21
Four Points by Sheraton Houston Intercontinental Airport

Holiday Inn Express & Suites Houston SW - Galleria Area by IHG

Holiday Inn Express & Suites Houston SW - Galleria Area by IHG
2.5 star property
9.6 km from South Main
8.0 out of 10, Very Good, (1,000 reviews)
"Clean room, friendly and responsive staff"
United States
Clara
The price is P5,977
P6,993 total
includes taxes & fees
Feb 18 - Feb 19
Holiday Inn Express & Suites Houston SW - Galleria Area by IHG

Comfort Suites Houston West at Clay Road

Comfort Suites Houston West at Clay Road
2.5 star property
22.8 km from South Main
8.4 out of 10, Very Good, (1,003 reviews)
"Friendly staff, breakfast excellent perfect location! Will definitely stay here again"
Canada
wanda
The price is P4,488
P5,252 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Suites Houston West at Clay Road

Hilton Garden Inn Houston NW America Plaza

Hilton Garden Inn Houston NW America Plaza
3.5 star property
25 km from South Main
8.6 out of 10, Excellent, (1,000 reviews)
"It was very relaxing and the staff are very friendly and helpful. "
United States
Chantel
The price is P5,424
P6,277 total
includes taxes & fees
Feb 22 - Feb 23
Hilton Garden Inn Houston NW America Plaza

Hampton Inn Houston-Brookhollow

Hampton Inn Houston-Brookhollow
2.5 star property
20.4 km from South Main
8.2 out of 10, Very Good, (1,002 reviews)
"The staff is awesome! What a great place to stay! "
United States
Cynthia
The price is P4,960
P5,803 total
includes taxes & fees
Feb 23 - Feb 24
Hampton Inn Houston-Brookhollow

GreenTree Inn Houston IAH Airport

GreenTree Inn Houston IAH Airport
2.0 star property
31.4 km from South Main
6.6 out of 10, (1,007 reviews)
"Staff was very friendly , room was very clean "
Canada
Charlette
The price is P3,134
P3,666 total
includes taxes & fees
Feb 17 - Feb 18
GreenTree Inn Houston IAH Airport

Sleep Inn & Suites Near Downtown North

Sleep Inn & Suites Near Downtown North
2.5 star property
Greater Heights, 14.2 km from South Main
8.4 out of 10, Very Good, (798 reviews)
"Great place to stay at "
United States
Audrey
The price is P5,170
P6,049 total
includes taxes & fees
Feb 22 - Feb 23
Sleep Inn & Suites Near Downtown North

La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD

La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD
3.0 star property
28.7 km from South Main
9.0 out of 10, Wonderful, (990 reviews)
"The hotel was very clean the staff was amazing. We enjoyed our stay"
United States
Teanna
The price is P6,313
P7,387 total
includes taxes & fees
Mar 2 - Mar 3
La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD

Home2 Suites by Hilton Houston IAH Airport Beltway 8

Home2 Suites by Hilton Houston IAH Airport Beltway 8
3.0 star property
29.9 km from South Main
8.4 out of 10, Very Good, (813 reviews)
"Great room close to airport "
United States
Kelli
The price is P4,826
P5,646 total
includes taxes & fees
Feb 23 - Feb 24
Home2 Suites by Hilton Houston IAH Airport Beltway 8

Hampton Inn & Suites Houston I-10 West Park Row

Hampton Inn & Suites Houston I-10 West Park Row
2.5 star property
29.4 km from South Main
8.8 out of 10, Excellent, (686 reviews)
"Room was very clean and front desk staff were great!"
United States
Bobby
The price is P4,647
P5,477 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn & Suites Houston I-10 West Park Row

Hilton Houston North

Hilton Houston North
3.5 star property
30.5 km from South Main
8.4 out of 10, Very Good, (1,002 reviews)
"I had a great stay at this hotel. The room was clean and comfortable."
United States
Victor
The price is P7,566
P8,852 total
includes taxes & fees
Feb 22 - Feb 23
Hilton Houston North

Doubletree by Hilton Houston Hobby Airport

Doubletree by Hilton Houston Hobby Airport
4.0 star property
Southeast Houston, 14.5 km from South Main
8.8 out of 10, Excellent, (1,006 reviews)
"Excellent stay! The room was very clean and comfortable, and the staff went above and beyond to be friendly and helpful. Check-in was smooth, the amenities were great, and the overall atmosphere made it a relaxing experience. I’d definitely stay here again!"
United States
Wayne
The price is P6,138
P7,252 total
includes taxes & fees
Feb 22 - Feb 23
Doubletree by Hilton Houston Hobby Airport

Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG
2.5 star property
The Galleria, 8.6 km from South Main
9.4 out of 10, Exceptional, (1,004 reviews)
"Clean room, great staff, great breakfast, comfortable bed. "
United States
Sabine
The price is P8,240
P9,641 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Express Houston - Galleria Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in South Main

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Candlewood Suites Houston Medical Center by IHG
2.5 star property
7.4
Good
835 reviews
View
Premium bedding, pillowtop beds, in-room safe, individually decorated
Wyndham Houston near NRG Park/Medical Center
3.5 star property
7.2
Good
1,218 reviews
View
Lobby
Wingate Houston near NRG Park/Medical Center
3.0 star property
6.6
1,000 reviews
View
Room
Comfort Suites Near Texas Medical Center - NRG Stadium
2.0 star property
9.0
Wonderful
6 reviews
View
Desk, cribs/infant beds, rollaway beds, free WiFi
Motel 6 Houston Medical Center Reliant Park
2.5 star property
5.6
471 reviews
View

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Top South Main Hotel Reviews

Find out more about South Main

Top reasons to visit South Main

  • Cultural Hub: South Main features a vibrant blend of historic and modern universities, art museums, and cultural events, enriching the experience for visitors.
  • Entertainment Options: Enjoy music concerts, movie showings, and various campus events that cater to diverse interests.
  • Convenient Location: Its proximity to downtown Houston makes South Main an ideal base for exploring local attractions.
  • Dynamic Sports Scene: Engage in numerous sports activities, with notable venues like Stockton Arena and Ballpark.
  • Diverse Accommodations: Choose from a wide range of hotels and aparthotels, ensuring a comfortable stay for all types of travellers.

Find great hotels near South Main

South Main, Houston, offers a diverse selection of accommodations, including both hotels and aparthotels, catering to various traveller needs. With a focus on business amenities, pet-friendly options, and an inclusive atmosphere for the LGBTQIA community, visitors can enjoy a welcoming and comfortable stay. Whether you're searching for the best hotels or top choices in Stockton, South Main provides a remarkable array of lodging to enhance your holiday experience.

  • Club Quarters Hotel Downtown, Houston: This 4-star hotel embodies a blend of modern convenience and a vibrant shopping atmosphere, making it ideal for business travellers and pet owners alike. Located 11.3km from South Main, it features a welcoming pet policy that includes free amenities for furry companions. Guests can enjoy the convenience of being in a bustling shopping district while benefiting from amenities such as food and water bowls for pets, ensuring a comfortable stay for all members of the family. The hotel's focus on business travel is evident in its well-equipped facilities, catering to those who need to balance work and play.
  • DoubleTree by Hilton Hotel & Suites Houston by the Galleria: Situated 8.0km from South Main, this 4-star hotel is the epitome of family-friendly hospitality with a special emphasis on inclusivity for the LGBTQIA community. The hotel offers a warm and welcoming atmosphere, complemented by thoughtful amenities for children, including cribs and window guards. Guests love the signature DoubleTree chocolate chip cookie upon arrival, adding a delightful touch to their stay. The proximity to the Galleria's shopping and dining options makes it a prime choice for families seeking both comfort and convenience.
  • The Royal Sonesta Houston Galleria: Just 8.0km from South Main, this 4-star hotel is perfect for those who appreciate a luxurious shopping experience combined with pet-friendly policies. The Royal Sonesta offers a sophisticated atmosphere with amenities tailored to both business and leisure travellers. Its pet policy includes restrictions to ensure a pleasant stay for all guests while offering the convenience of being located in a vibrant shopping district. Guests are particularly fond of the elegant rooms and attentive service, making it a top choice for those seeking a stylish escape.

Where to stay near South Main

Visitors to South Main, Houston, will discover a vibrant mix of culture and urban charm. This neighbourhood boasts a convenient location near downtown, making it an ideal base for exploring local attractions. Enjoy family-friendly activities, experience the bustling atmosphere of Main Street, and indulge in the dynamic sports scene. With its friendly people and rich cultural experiences, South Main promises a memorable getaway that caters to both business and leisure travellers alike.

  • Houston: As a vibrant metropolis, Houston serves as the heart of South Main. This bustling city is a hub for family-oriented activities, business ventures, and entertainment experiences. With visitor numbers peaking in March, May, and July, Houston offers a dynamic atmosphere enriched with shopping centres, music concerts, and lively sports stadiums. Explore local landmarks such as the event conference venues and convention centres, which host a variety of attractions throughout the year, ensuring a memorable travel experience.
  • Texas Medical Center: Located a mere 3.2km from South Main, the Texas Medical Center is a distinguished neighbourhood renowned for its focus on business, culture, and education. Visitors flock here mainly in April, July, and September, drawn by its modern college universities and cutting-edge research facilities. The area boasts an array of shopping malls and centres, making it a convenient spot to combine leisure with learning. The nearby sports stadium adds an extra layer of excitement for sports enthusiasts.
  • Willow Meadows/Willowbend Area: Also situated 3.2km from South Main, the Willow Meadows/Willowbend Area invites travellers seeking a mix of business, sports, and city experiences. With peak visitation in March, May, and July, this neighbourhood is perfect for enjoying shopping centres, music concerts, and vibrant community events. Local landmarks, including sports facilities and modern educational institutions, contribute to the area's charm, making it a delightful destination for both relaxation and exploration.

Things to do near South Main

South Main offers a delightful mix of activities for sports enthusiasts and culture seekers alike. Enjoy educational opportunities, music concerts, and vibrant shopping experiences at the local mall centre. Be sure to catch movie showings and engage in various campus events, all set against the backdrop of Houston's dynamic atmosphere. Whether you're in the mood for entertainment or learning, South Main has something to offer every visitor.

Shopping

Experience shopping in South Main with nearby gems like The Galleria, 8.0km away, offering a vibrant mix of entertainment and family-friendly vibes. Also, visit River Oaks District, a public market just 8.0km away, where you’ll find a blend of city and business atmospheres for unique gifts.

Recreation

At the nearby NRG Astrodome, immerse yourself in the exhilarating atmosphere of live sports events. Experience the upscale charm of the Houston Polo Club, where you can indulge in luxury while enjoying polo matches. The Toyota Center offers a vibrant sports environment, perfect for an energetic outing.

Adventure

Experience the thrill of free-fall at iFLY Indoor Skydiving, located 16.1km from South Main. For family fun, visit Chancellors Family Center, 8.0km away, which offers various adventure activities. Also, enjoy a spirited game at Homer Ford Tennis Center, situated 8.0km from South Main.

Nightlife

The nightlife in South Main offers a delightful mix. Enjoy a romantic show at Main Street Theater, or catch a family-friendly film at Regal Edwards Greenway Grand Palace. For a bit of fun, head to Zuma Fun Center for arcade adventures that the whole family will enjoy.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for South Main

To save on your trip to South Main, consider visiting in August or December to January when accommodation prices are lower. Sundays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to filter for eco-friendly hotels and sort by price to find the best deals. Additionally, book a package deal that combines flights, accommodation, and activities for added savings. Explore free attractions in the area and utilise public transport for an economical way to get around, ensuring a budget-friendly experience.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around South Main are August and December to January, where the prices are slightly lower. This is in comparison to March to May, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around South Main is Sunday. The most expensive day to stay around South Main is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to customise your preferences, such as your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and eco-friendly accommodation options currently available. To find the most affordable prices and best deals, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your South Main hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near South Main

South Main in Houston, Texas, offers a diverse range of activities ideal for sports enthusiasts, business travellers, and culture seekers alike. Visitors can explore historic and modern universities, as well as art museums, providing enriching experiences for families and culture lovers. Notable attractions include Stockton Arena and Stockton Ballpark, along with various nearby points of interest, ensuring a memorable stay for all who venture to this vibrant area.

  • Lakewood Church: Experience the vibrant atmosphere of Lakewood Church, known for its uplifting services and community spirit. This expansive venue, located 6.4km from South Main, hosts inspiring events and concerts, making it a cultural hub for visitors and locals alike.
  • Houston Baptist University: Discover the modern architecture and lively environment of Houston Baptist University, situated 9.7km from South Main. This institution boasts a diverse student body and offers various events, providing a genuine city vibe that reflects the heart of Houston.
  • Houston Center for Photography: Immerse yourself in the artistic world at the Houston Center for Photography, located 8.0km from South Main. This venue showcases stunning photographic exhibitions and workshops, celebrating creativity and culture in a welcoming setting.

Best time to go to South Main

The best time to visit South Main is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January54.1°F (12.3°C)Light RainMostly SunnyAverageSlightly Low
February57.0°F (13.9°C)Light RainMostly CloudyAverageAverage
March63.9°F (17.7°C)Light RainMostly SunnyAverageSlightly High
April69.6°F (20.9°C)Light RainMostly SunnyModerately HighSlightly High
May76.6°F (24.8°C)Light RainMostly SunnyAverageSlightly High
June82.8°F (28.2°C)Light RainMostly SunnyModerately HighAverage
July84.2°F (29.0°C)Light RainMostly SunnyModerately HighAverage
August84.9°F (29.4°C)Light RainMostly SunnyAverageSlightly Low
September80.6°F (27.0°C)Light RainMostly SunnyAverageAverage
October72.7°F (22.6°C)Light RainMostly SunnyModerately LowAverage
November62.8°F (17.1°C)Light RainMostly SunnyModerately LowAverage
December57.4°F (14.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to South Main

Travelling to South Main, Houston, is convenient with three major airports nearby. Houston, TX (IAH-George Bush Intercontinental) is situated 35.4km away, offering excellent hotels like the DoubleTree by Hilton Houston Intercontinental Airport, 4.8km from the airport, and the Houston Airport Marriott at George Bush Intercontinental, which is located on-site. Alternatively, Houston, TX (HOU-William P. Hobby) is 14.5km away, with luxurious options such as the JW Marriott Houston Downtown. Lastly, Houston, TX (EFD-Ellington Field) lies 25.7km from South Main, featuring hotels like the Doubletree by Hilton Houston Hobby Airport, 11.3km from the airport. Each airport provides efficient transportation services to their respective hotels.

Frequently asked questions

What is South Main like?
You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.
Where is the best hotel for a stay in South Main?
Based on Expedia customer reviews, Comfort Suites Houston near Medical Center- NRG Stadium is the highest ranked property in South Main. This hotel is a short 10-minute walk from NRG Stadium, and it offers free breakfast and a fitness center. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.
How many hotels will I be able to find in South Main?
If you're searching for places to stay in Houston, Expedia has something to meet your needs with 63 South Main hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.
What can I see and do in this Houston neighborhood?
NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.
How can I get around South Main and the greater Houston area?
Ready to get out and explore the city? Fannin South Station is the closest metro station.