South Main

Houston

Photo by Hazem Abdul
Photo by Hazem Abdul

Popular places to visit

George R. Brown Convention Center

George R. Brown Convention Center

During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the great live music and acclaimed art scene in this vibrant area.

George R. Brown Convention Center
NASA Johnson Space Center

NASA Johnson Space Center

After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.

NASA Johnson Space Center
Daikin Park

Daikin Park

Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area.

Daikin Park
Toyota Center

Toyota Center

Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed art scene and lively festivals in this vibrant area.

Toyota Center
Rice University

Rice University

Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed art scene and lively festivals.

Rice University
University of Houston

University of Houston

Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the great live music and acclaimed art scene in this vibrant area.

University of Houston

Things to do

Houston Museum of Natural Sciences: Planetarium Ticket

Houston Museum of Natural Sciences: Planetarium Ticket

P698
per adult
82% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
Houston: Downtown Aquarium All Day Pass

Houston: Downtown Aquarium All Day Pass

P1,570
per adult
Houston: Downtown Aquarium All Day Pass
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

P698
per adult
80% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
Drip Bear Paint & Sip Experience

Drip Bear Paint & Sip Experience

P2,617
per adult
Drip Bear Paint & Sip Experience
Color Factory Houston Ticket

Color Factory Houston Ticket

P1,687
per adult
Color Factory Houston Ticket
Houston City Tour and Downtown Aquarium All Rides Pass

Houston City Tour and Downtown Aquarium All Rides Pass

P3,778
per adult
98% of travellers recommend
Houston City Tour and Downtown Aquarium All Rides Pass
See all activities in Houston

Top hotels in South Main

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive, Houston, TX
The price is P7,352 per night from Aug 24 to Aug 25
P7,352
P8,602 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
7/10 Good! (1,127 reviews)
"It was quiet and close to our event. It was very clean and staff was helpful"

Reviewed on Aug 19, 2025

Wyndham Houston near NRG Park/Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
The price is P6,972 per night from Aug 28 to Aug 29
P6,972
P8,215 total
Aug 28 - Aug 29
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,398 reviews)
"Great"

Reviewed on Aug 17, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
The price is P5,985 per night from Aug 28 to Aug 29
P5,985
P7,002 total
Aug 28 - Aug 29
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (3,621 reviews)
"The check in process and the help of staff amazing! Also the restaurant. Thanks!"

Reviewed on Aug 18, 2025

Club Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
The price is P4,976 per night from Sep 7 to Sep 8
P4,976
P5,888 total
Sep 7 - Sep 8
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,521 reviews)
Super friendly staff, and great rates.
"We were there because of a serious illness in the family. The staff was incredibly nice and supportive. The rooms are clean, quiet, comfortable and well kept. The shuttle is easy to use to any hospital in the medical center, or it is short walk."

Reviewed on Aug 16, 2025

Hilton Houston Plaza/Medical Center
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St, Houston, TX
The price is P8,150 per night from Aug 28 to Aug 29
P8,150
P9,536 total
Aug 28 - Aug 29
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,676 reviews)
"Was really great , breakfast was really good taste and customer service 10/10"

Reviewed on Aug 18, 2025

The Whitehall Houston
Holiday Inn Houston Downtown by IHG

Holiday Inn Houston Downtown by IHG

3 out of 5
1616 Main St, Houston, TX
Fully refundable
The price is P6,168 per night from Aug 31 to Sep 1
P6,168
P8,219 total
Aug 31 - Sep 1
includes taxes & fees
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,435 reviews)
"The staff was very friendly and helpful. The room was small but clean and beds were comfortable."

Reviewed on Aug 17, 2025

Holiday Inn Houston Downtown by IHG
See all 6,369 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

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Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
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The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

The Galleria
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Midtown

The restaurants and live music are just a few things visitors like about Midtown. Continental Club and Midtown Arts and Theater Center Houston are worthwhile spots to check out, and you can hop on the metro at McGowen Station or Ensemble/HCC Station to get around the larger area.

Midtown

South Main