South Main

Houston

Photo by Hazem Abdul

Popular places to visit

Things to do


Top hotels in South Main

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive, Houston, TX
The price is P7,365 per night from Aug 12 to Aug 13
P7,365
P8,617 total
Aug 12 - Aug 13
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
7/10 Good! (1,137 reviews)
"It was a nice experience overall , although they should have more checking in desks on high attendance events ..the check in took around 2 standing hrs On the otherside the staff always kept a smile and good service"

Reviewed on Aug 7, 2025

Wyndham Houston near NRG Park/Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Stay at this 4.5-star luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (1,735 reviews)
"Everything was nice and cozy and clean pricey though The valet was 59 a night the restaurant monarch was lovely very pricey but noce"

Reviewed on Aug 5, 2025

Hotel Zaza Houston Museum District
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St, Houston, TX
The price is P8,165 per night from Aug 21 to Aug 22
P8,165
P9,553 total
Aug 21 - Aug 22
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,661 reviews)
"I ate at the hotel restaurant and the food was good. The area has lots of dining options within walking distance."

Reviewed on Aug 9, 2025

The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
The price is P6,173 per night from Sep 9 to Sep 10
P6,173
P7,273 total
Sep 9 - Sep 10
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (2,348 reviews)
"Nice & quiet. Room was spacious with a nice balcony"

Reviewed on Aug 7, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
The price is P5,244 per night from Sep 5 to Sep 6
P5,244
P6,201 total
Sep 5 - Sep 6
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,503 reviews)
"We loved the convenience of the location and the shuttle service, but the elevators were in disrepair and they only had one, which created a delay. The pool needed service while we were there but we called the lobby and that was quickly corrected. There were no ice machines on the guest floors. This ..."

Reviewed on Aug 8, 2025

Hilton Houston Plaza/Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is P5,995 per night from Aug 14 to Aug 15
P5,995
P7,014 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,582 reviews)
"I loved how seamless the check in process was."

Reviewed on Aug 7, 2025

Club Quarters Hotel Downtown, Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

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Texas Medical Center

Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Texas Medical Center
Hermann Park featuring landscape views and a park

Houston Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park featuring landscape views and a park

South Central Houston

If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
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The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

The Galleria
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Midtown

The restaurants and live music are just a few things visitors like about Midtown. Continental Club and Midtown Arts and Theater Center Houston are worthwhile spots to check out, and you can hop on the metro at McGowen Station or Ensemble/HCC Station to get around the larger area.

Midtown

South Main