Photo by Ryan Coleman

Sikeston Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 20 - Nov 21
Tomorrow
Nov 21 - Nov 22
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Sikeston hotels

Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"Clean room, great location and friendly staff"
United States
Mark
The price is P5,657
P6,504 total
includes taxes & fees
Nov 27 - Nov 28
Drury Inn & Suites Sikeston, MO
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (426)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is P5,610
P6,352 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn Sikeston
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
The price is P4,537
P5,215 total
includes taxes & fees
Dec 1 - Dec 2
Pear Tree Inn Sikeston
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is P3,707
P4,224 total
includes taxes & fees
Nov 24 - Nov 25
Days Inn and Suites by Wyndham Sikeston
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (708)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is P3,859
P4,399 total
includes taxes & fees
Nov 21 - Nov 22
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1004)
"Very convenient and great breakfast "
United States
Duwaine
The price is P4,958
P5,651 total
includes taxes & fees
Nov 27 - Nov 28
Best Western Plus Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (439)
"Well maintained property. We’ll stop again should we need to."
United States
Janet DeJean
The price is P5,893
P6,672 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express & Suites Sikeston Southwest by IHG
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (37)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is P5,959
P6,747 total
includes taxes & fees
Nov 27 - Nov 28
Fairfield Inn & Suites by Marriott Sikeston
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (116)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is P3,149
P3,747 total
includes taxes & fees
Nov 21 - Nov 22
Country Yard Inn and Suite
Desk, laptop workspace, blackout drapes, free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (559)
"The room was good a/c kept it cold "
United States
Mary
The price is P3,310
P3,772 total
includes taxes & fees
Nov 23 - Nov 24
Super 8 by Wyndham Sikeston/Miner Area
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1007)
"This was a wonderful stay. We will definitely stay again when we are in town!"
United States
Trista
The price is P5,303
P5,607 total
includes taxes & fees
Nov 25 - Nov 26
Drury Inn & Suites Jackson MO
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
8.4 out of 10, Very Good, (5)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is P7,130
P8,073 total
includes taxes & fees
Dec 21 - Dec 22
TownePlace Suites by Marriott Sikeston
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
The price is P4,124
P4,653 total
includes taxes & fees
Dec 2 - Dec 3
Pear Tree Inn Cape Girardeau West
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (651)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
The price is P4,959
P5,367 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (277)
"Room was clean, breakfast was very good. "
United States
Connie
The price is P4,959
P5,652 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn & Suites Sikeston I-55
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Very nice stay."
United States
Charity
The price is P5,303
P5,982 total
includes taxes & fees
Dec 2 - Dec 3
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is P4,124
P4,653 total
includes taxes & fees
Dec 2 - Dec 3
Pear Tree Inn Cape Girardeau Near the Medical Center
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "
United States
Sandra
The price is P5,309
P5,989 total
includes taxes & fees
Nov 30 - Dec 1
Drury Inn & Suites Cape Girardeau
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is P5,369
P6,056 total
includes taxes & fees
Nov 30 - Dec 1
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (608)
"Staff was great! Room was nice. "
United States
Lana
The price is P3,259
P3,618 total
includes taxes & fees
Nov 23 - Nov 24
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Showing deals for:Nov 28 - Nov 30

Image gallery for Tru By Hilton Cape Girardeau

Room

Tru By Hilton Cape Girardeau

2.5 star property
Cape Girardeau
9.6/10Exceptional (94 reviews)
20% off
Price is P5,846
P13,307 total
includes taxes & fees
Tru By Hilton Cape Girardeau
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Check out hotels with free breakfast in Sikeston

Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (651)
The price is P4,959
P5,367 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
View all properties

Pet-friendly hotels in Sikeston you'll enjoy

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
The price is P5,303
P5,982 total
includes taxes & fees
Dec 2 - Dec 3
Drury Plaza Hotel Cape Girardeau Conference Center
View all properties

These family-friendly hotels in Sikeston may fit your trip

Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (651)
The price is P4,959
P5,367 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Stay near popular Sikeston attractions

City of Miner Convention Center

Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Sikeston Depot Museum

3.8/5 (33 reviews)
You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants.
See properties

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Clean and good service "
Henry 1-night trip
Posted 2 days ago
Pear Tree Inn Cape Girardeau West

More cheap stays in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is P3,707 per night from Nov 24 to Nov 25
P3,707
P4,224 total
Nov 24 - Nov 25
includes taxes & fees
7.2/10 Good! (1,000 reviews)

Frequently asked questions

Where is the best place to stay in Sikeston?
Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.
What's the best hotel for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.
What is the top LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best pet-friendly accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.
What are some accommodations with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.
What is staying in Sikeston like?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.
What are the top places to visit in Sikeston?
A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.
What's the seasonal weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

Explore a world of travel with Expedia