Sikeston Trips (flight + hotel)

Photo by Ryan Coleman

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Top hotels in Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P5,125 per night from Aug 10 to Aug 11
P5,125
P5,841 total
Aug 10 - Aug 11
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
"Staff was excellent. Pool was nice and warm too!"

Reviewed on Aug 2, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P5,234 per night from Aug 17 to Aug 18
P5,234
P6,018 total
Aug 17 - Aug 18
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
"Enjoyed everything"

Reviewed on Jul 19, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is P4,202 per night from Aug 18 to Aug 19
P4,202
P4,790 total
Aug 18 - Aug 19
includes taxes & fees
7.2/10 Good! (1,001 reviews)
Nice, comfortable
"The staff and room were nice. I did not like that they actually took a deposit out of my account and put it back instead of just held it like other hotels I've been at."

Reviewed on Jul 26, 2025

Days Inn and Suites by Wyndham Sikeston
See all 263 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sikeston vacation package cost?
You'll find cheap prices on Expedia for your Sikeston getaway. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Sikeston costs.
What are the cheapest months to go to Sikeston?
January, February and September are the best times to look for cheap Sikeston vacation packages. Opting to travel in quieter periods means you'll typically find better prices on hotels and flights.
How many days is enough for Sikeston?
You can easily see all the top attractions in Sikeston in a few days, including the popular Sikeston Depot Museum. If you want an extended Sikeston vacation, check out which kind of excursions and activities are available nearby.
Is it worth booking a vacation package to Sikeston?
Sikeston has everything you need for an unforgettable trip. Begin your Sikeston vacation on a high note by exploring top attractions like Central Park.
How to find the best Sikeston package deals?
Use Expedia's filters to find some great Sikeston package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Sikeston package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Sikeston vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking stays and flights separately. Better still, you can tailor your Sikeston escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sikeston?
Enjoy incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Sikeston trip.
How to plan a trip to Sikeston?

  1. Choose the right time to travel: Your schedule, favorite season and the type of weather you like can all impact your decision on when to visit Sikeston.
  2. Set your budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Sikeston. Then, pick a hotel that suits your budget, whether that's an economical stay or a lavish retreat.
  3. Determine how many days away: Start by compiling a list of the attractions and activities you want to experience in Sikeston. Then, estimate how long you'll need at each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, hotels, car rental and more into a personalized Sikeston vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.