Sikeston

Travel Guide

A tree with sunlight filtering through its leaves, creating a warm glow.
A person walking through a cornfield.
A building with three tall chimneys, surrounded by blooming trees with pink and white flowers.
A sign for Lambert's, a place of worship.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is P5,916 per night from Nov 15 to Nov 16
P5,916
P6,802 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,002 reviews)
"The hotel was very clean. Room was spacious and bed was comfortable. Staff were friendly"

Reviewed on Nov 6, 2026

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is P4,173 per night from Dec 11 to Dec 12
P4,173
P4,757 total
Dec 11 - Dec 12
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is P6,367 per night from Nov 19 to Nov 20
P6,367
P7,241 total
Nov 19 - Nov 20
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
Hampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
9.4/10 Exceptional! (22 reviews)
"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

Reviewed on Jun 11, 2026

Urban Lofts
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
9.6/10 Exceptional! (14 reviews)
"This is a great boutique hotel in Perryville with reasonable fees. I have stayed here twice on my way from Iowa to Mississippi. I recommend staying here if you plan to visit Perryville or are passing through."

Reviewed on Nov 10, 2026

The Atrium - A Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions