Panama City Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 23 - Jan 25
In two months
Mar 6 - Mar 8
In three months
Apr 3 - Apr 5
In four months
May 1 - May 3

Our top choices for Panama City vacation rentals

Restaurant
Las Clementinas

Aparthotel in Casco Viejo

Las Clementinas
3.5 star property
9.4 out of 10, Exceptional, (173 reviews)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is P8,213
P9,034 total
includes taxes & fees
Feb 2 - Feb 3
Las Clementinas
Interior detail
La Isabela Suites

Aparthotel in Casco Viejo

La Isabela Suites
3.5 star property
10.0 out of 10, Exceptional, (172 reviews)
"Excellent place to stay in the Casco Viejo "
United States
Zoe M
La Isabela Suites
Living area
La Moderna by Wynwood House

Apartment in Casco Viejo

La Moderna by Wynwood House
3.0 star property
7.4 out of 10, Good, (42 reviews)
"The nightlife around there was incredible"
United States
Felix
The price is P3,385
P5,679 total
includes taxes & fees
Jan 12 - Jan 13
La Moderna by Wynwood House
Reception
Torres de Alba Hotel & Suites

Aparthotel in Bella Vista

Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (490 reviews)
"Always love the rooms there."
United States
Treisha
Torres de Alba Hotel & Suites
50-inch LED TV with satellite channels
Arcadia Condo Suites

Aparthotel in Costa del Este

Arcadia Condo Suites
2.5 star property
9.4 out of 10, Exceptional, (189 reviews)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is P4,907
P8,135 total
includes taxes & fees
Feb 9 - Feb 10
Arcadia Condo Suites
Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Apartment in Las Mañanitas

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
The price is P4,482
P5,620 total
includes taxes & fees
Jan 15 - Jan 16
Swette Love 10 Minutes From the Airport Tocumen
Free WiFi, bed sheets
La Palma Aparta Suite

Apartment in Amador

La Palma Aparta Suite
3.0 star property
8.0 out of 10, Very Good, (2 reviews)
"All ways clean and ready to used ,no buddy "
United States
Alberto
The price is P2,809
P4,867 total
includes taxes & fees
Jan 13 - Jan 14
La Palma Aparta Suite
Dining room
Mini Design By Wynwood House

Apartment in Bella Vista

Mini Design By Wynwood House
2.0 star property
The price is P6,560
P8,845 total
includes taxes & fees
Feb 8 - Feb 9
Mini Design By Wynwood House
Living area
Centriqo by Wynwood house

Apartment in Veracruz

Centriqo by Wynwood house
3.0 star property
The price is P7,040
P9,699 total
includes taxes & fees
Jan 12 - Jan 13
Centriqo by Wynwood house
Outdoor pool
Studio Apartment with Ocean View

Apartment in Calidonia

Studio Apartment with Ocean View
3.0 star property
8.0 out of 10, Very Good, (2 reviews)
"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"
United States
Gwendolyn
The price is P3,852
P4,237 total
includes taxes & fees
Jan 15 - Jan 16
Studio Apartment with Ocean View
Room
w Engaging 1BR w Balcony in San Francisco

Apartment in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
The price is P6,890
P9,437 total
includes taxes & fees
Feb 1 - Feb 2
w Engaging 1BR w Balcony in San Francisco
Exterior
Yoo Apartamento

Apartment in Bella Vista

Yoo Apartamento
3.0 star property
9.6 out of 10, Exceptional, (14 reviews)
"Great location"
United States
Jimmy Lee
The price is P5,215
P8,344 total
includes taxes & fees
Jan 13 - Jan 14
Yoo Apartamento
Premium bedding, soundproofing, iron/ironing board, free WiFi
Casa Contemporanea by Wynwood House

Apartment in Casco Viejo

Casa Contemporanea by Wynwood House
4.0 star property
8.2 out of 10, Very Good, (20 reviews)
"Great place!"
United States
Jad
The price is P7,307
P9,519 total
includes taxes & fees
Feb 1 - Feb 2
Casa Contemporanea by Wynwood House
Outdoor pool
Wanders Panama by Boutique Apartments

Apartment in San Francisco

Wanders Panama by Boutique Apartments
4.0 star property
10.0 out of 10, Exceptional, (2 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is P12,906
P23,258 total
includes taxes & fees
Feb 9 - Feb 10
Wanders Panama by Boutique Apartments
Living area
Living 73 Panamá by Boutique Apartments

Apartment in San Francisco

Living 73 Panamá by Boutique Apartments
3.0 star property
The price is P4,388
P13,728 total
includes taxes & fees
Feb 1 - Feb 2
Living 73 Panamá by Boutique Apartments
Living area
Casa Lefevre By Wynwood House

Apartment in Casco Viejo

Casa Lefevre By Wynwood House
3.5 star property
9.0 out of 10, Wonderful, (4 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is P8,806
P11,316 total
includes taxes & fees
Jan 15 - Jan 16
Casa Lefevre By Wynwood House
Pool
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Apartment in José Domingo Espinar

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
The price is P5,276
P5,803 total
includes taxes & fees
Jan 12 - Jan 13
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Panama City Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"All good "
brian 1-night trip
Posted 2 days ago
Ramada Plaza by Wyndham Panama Punta Pacifica

Find out more about Panama City

Search for holiday rentals in Panama City on Expedia! You can easily find your home rentals, villas, holiday apartments in Panama City using one of the methods below:

  • View our selection of featured holiday rentals in Panama City
  • Use the map to find apartments and other holiday homes in the Panama City neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Panama City while they last

Look no further and take a look at our great range of rental properties in Panama City!

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

How many vacation rentals are there in Panama City?

With 52 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.