Panama City Vacation Rentals

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Check prices for these dates

In two weeks
Apr 24 - Apr 26
In two months
Jun 5 - Jun 7
In three months
Jul 3 - Jul 5
In four months
Jul 31 - Aug 2

Our top choices for Panama City vacation rentals

Interior detail

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (190 reviews)
"Staying and active in rural Boquete Panama is both a treat and a retreat of relaxation."
United States
Jerry
The price is P8,908
P9,799 total
includes taxes & fees
May 3 - May 4
La Isabela Suites
50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (262 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is P7,199
P10,690 total
includes taxes & fees
Apr 15 - Apr 16
Arcadia Condo Suites
Restaurant

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (185 reviews)
"Best of the best, as always!"
United States
Rebecca
The price is P7,653
P8,418 total
includes taxes & fees
Apr 13 - Apr 14
Las Clementinas
TV

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is P3,359
P12,598 total
includes taxes & fees
Apr 13 - Apr 14
Living 73 Panamá by Boutique Apartments
Dining room

Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (1 review)
The price is P10,474
P13,171 total
includes taxes & fees
Apr 13 - Apr 14
Mini Design By Wynwood House
2 bedrooms, Internet

w Homely 2BR With Balcony in Panama

w Homely 2BR With Balcony in Panama
2.0 star property
Casco Viejo
The price is P6,966
P10,780 total
includes taxes & fees
Apr 13 - Apr 14
w Homely 2BR With Balcony in Panama
Exterior

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very Good, (85 reviews)
"The stay was wonderful. Highly recommend. Great value. "
Canada
Joseph
The price is P4,589
P13,387 total
includes taxes & fees
Apr 13 - Apr 14
Yoo Panamá by Boutique Apartments
Premium bedding, soundproofing, iron/ironing board, free WiFi

Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House
4.0 star property
Casco Viejo
8.2 out of 10, Very Good, (22 reviews)
"Cute place, well located. "
Canada
Stephanie
The price is P9,664
P12,130 total
includes taxes & fees
Apr 13 - Apr 14
Casa Contemporanea by Wynwood House
Outdoor pool

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is P9,178
P19,268 total
includes taxes & fees
May 11 - May 12
Wanders Panama by Boutique Apartments
Reception

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (538 reviews)
"Very clean and amazing stay "
United States
Reinaldo
The price is P5,549
P6,104 total
includes taxes & fees
Apr 13 - Apr 14
Torres de Alba Hotel & Suites
Living area

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (12 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is P6,996
P9,345 total
includes taxes & fees
Apr 20 - Apr 21
Casa Lefevre By Wynwood House
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (87 reviews)
"The staff was absolutely phenomenal! So kind and accommodating even when certain events were out of their control they were still so wonderful!"
United States
Nicole
The price is P5,966
P8,362 total
includes taxes & fees
Apr 13 - Apr 14
Casco View Apartments
Living area

Casa La Costa By Wynwood House

Casa La Costa By Wynwood House
3.5 star property
Casco Viejo
8.6 out of 10, Excellent, (27 reviews)
"Great location. At the border of renovated areas but an extremely go deal for this great property. "
United States
William
The price is P7,235
P9,608 total
includes taxes & fees
Apr 13 - Apr 14
Casa La Costa By Wynwood House
Free WiFi, bed sheets

La Palma Experience

La Palma Experience
3.0 star property
Amador
8.4 out of 10, Very Good, (7 reviews)
"All ways clean and ready to used ,no buddy "
United States
Alberto
The price is P3,893
P5,002 total
includes taxes & fees
Apr 13 - Apr 14
La Palma Experience
Living area

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (184 reviews)
"Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! "
United States
Andrena
The price is P2,969
P11,677 total
includes taxes & fees
Apr 13 - Apr 14
Boutique Apartments Panamá Coco del Mar
Internet

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is P7,262
P9,721 total
includes taxes & fees
Apr 19 - Apr 20
w Bright 1BR w Private Balcony in San Francisco
Living area

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (24 reviews)
"Super "
France
Stephen
The price is P6,371
P8,658 total
includes taxes & fees
Apr 23 - Apr 24
Casa Love by Wynwood House
Living area

La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.5 star property
El Chorrillo
9.0 out of 10, Wonderful, (52 reviews)
"Second stay here and just as perfect as our first stay. "
United States
G. Jeffrey
The price is P8,698
P11,068 total
includes taxes & fees
Apr 15 - Apr 16
La Cuadra by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Principe Hotel and Suites

Principe Hotel and Suites

8/10 Good
"The ac comes on by a timer and the tv only show in Spanish."
JUANITA 6-night trip
Posted 1 hour ago
Principe Hotel and Suites

Find out more about Panama City

Search for holiday rentals in Panama City on Expedia! You can easily find your home rentals, villas, holiday apartments in Panama City using one of the methods below:

  • View our selection of featured holiday rentals in Panama City
  • Use the map to find apartments and other holiday homes in the Panama City neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Panama City while they last

Look no further and take a look at our great range of rental properties in Panama City!

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and lively bars in Panama City. While you're in the area, grab a bite or have a drink at the top-notch restaurants and cafes.

How many vacation rentals are there in Panama City?

With 53 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.