Panama City Vacation Rentals

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Check prices for these dates

In two weeks
Mar 13 - Mar 15
In two months
Apr 24 - Apr 26
In three months
May 22 - May 24
In four months
Jun 19 - Jun 21

Our top choices for Panama City vacation rentals

50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (221 reviews)
"Really loved this place"
United States
Alejandra
The price is P4,783
P7,930 total
includes taxes & fees
Mar 1 - Mar 2
Arcadia Condo Suites
Exterior

Luxury Apartment Piso 35 with City View

Luxury Apartment Piso 35 with City View
2.0 star property
Bella Vista
The price is P4,117
P4,529 total
includes taxes & fees
Mar 16 - Mar 17
Luxury Apartment Piso 35 with City View
1 bedroom

Dovle 510 in Ciudad de Panam

Dovle 510 in Ciudad de Panam
2.0 star property
San Francisco
The price is P7,327
P8,060 total
includes taxes & fees
Mar 1 - Mar 2
Dovle 510 in Ciudad de Panam
Restaurant

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (182 reviews)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is P9,171
P10,089 total
includes taxes & fees
Mar 23 - Mar 24
Las Clementinas
Living area

Centriqo by Wynwood house

Centriqo by Wynwood house
3.0 star property
Veracruz
The price is P6,192
P8,718 total
includes taxes & fees
Mar 1 - Mar 2
Centriqo by Wynwood house
Interior detail

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (180 reviews)
"Excellent place to stay in the Casco Viejo "
United States
Zoe M
La Isabela Suites
Living area

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.5 star property
Casco Viejo
9.2 out of 10, Wonderful, (7 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is P8,133
P10,535 total
includes taxes & fees
Feb 26 - Feb 27
Casa Lefevre By Wynwood House
Dining room

Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
The price is P7,486
P9,824 total
includes taxes & fees
Mar 8 - Mar 9
Mini Design By Wynwood House
Exterior

Yoo by Wynwood House

Yoo by Wynwood House
4.0 star property
Calidonia
9.2 out of 10, Wonderful, (5 reviews)
"I will be back!"
United States
Jeffrey
The price is P10,074
P13,115 total
includes taxes & fees
Mar 5 - Mar 6
Yoo by Wynwood House
Outdoor pool

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is P11,437
P21,413 total
includes taxes & fees
Mar 9 - Mar 10
Wanders Panama by Boutique Apartments
Living area

La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.5 star property
El Chorrillo
9.0 out of 10, Wonderful, (49 reviews)
"Superb customer service. Instant responsiveness. Almost miraculous. "
United States
Peter
The price is P5,499
P7,782 total
includes taxes & fees
Mar 3 - Mar 4
La Cuadra by Wynwood House
2 bedrooms, Internet

w Homely 2BR With Balcony in Panama

w Homely 2BR With Balcony in Panama
2.0 star property
Casco Viejo
The price is P8,326
P12,446 total
includes taxes & fees
Mar 1 - Mar 2
w Homely 2BR With Balcony in Panama
Free WiFi, bed sheets

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
8.4 out of 10, Very Good, (7 reviews)
"All ways clean and ready to used ,no buddy "
United States
Alberto
The price is P4,431
P5,567 total
includes taxes & fees
Feb 26 - Feb 27
La Palma Aparta Suite
Exterior

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very Good, (63 reviews)
"Great location, wonderful views, spacious apartment, with comfortable bed and good ac. Amenities in the building are great too."
United States
alan
The price is P3,379
P11,747 total
includes taxes & fees
Mar 2 - Mar 3
Yoo Panamá by Boutique Apartments
Living area

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
8.8 out of 10, Excellent, (23 reviews)
"Large, clean rooms, lots of space. Great bathroom. Great location. "
United States
Joette
The price is P4,852
P7,244 total
includes taxes & fees
Mar 5 - Mar 6
Casa Love by Wynwood House
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (74 reviews)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments
Outdoor pool

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (692 reviews)
"Enjoyed the stay"
United States
Breneda
The price is P7,807
P8,588 total
includes taxes & fees
Mar 22 - Mar 23
Marriott Executive Apartments Panama City, Finisterre
Outdoor pool

Studio Apartment with Ocean View

Studio Apartment with Ocean View
3.0 star property
Calidonia
8.0 out of 10, Very Good, (2 reviews)
"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"
United States
Gwendolyn
The price is P3,755
P4,130 total
includes taxes & fees
Mar 4 - Mar 5
Studio Apartment with Ocean View
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"The place is beautiful and the staffs were so genuine. "
Gustavo 4-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama

Find out more about Panama City

Search for holiday rentals in Panama City on Expedia! You can easily find your home rentals, villas, holiday apartments in Panama City using one of the methods below:

  • View our selection of featured holiday rentals in Panama City
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  • Enter your travel dates to view the best deals on holiday rentals in Panama City while they last

Look no further and take a look at our great range of rental properties in Panama City!

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

How many vacation rentals are there in Panama City?

With 54 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include Interoceanic Canal Museum and Biomuseo, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.