Photo by Catherine Edejer-McCormick

Downtown South San Francisco Hotels near San Francisco

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Downtown South San Francisco, San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very Good, (2022)
"Great place, Delicious Breakfast."
The price is P6,458
P7,566 total
includes taxes & fees
Jul 27 - Jul 28
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1001)
"Was a great and affordable place to get near sfo"
Inn By The SFO

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (922)
"Great place, clean and quiet!! "
The price is P5,613
P6,582 total
includes taxes & fees
Jul 9 - Jul 10
Airport Inn

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is P3,005
P7,818 total
includes taxes & fees
Jul 9 - Jul 10
Miller Apartments

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
9.0 out of 10, Wonderful, (2026)
"Nice stay - clean, freindly staff."
The price is P7,427
P10,442 total
includes taxes & fees
Jul 21 - Jul 22
Holiday Inn Express and Suites Fisherman's Wharf by IHG

FOUND Hotel Carlton, Nob Hill

2.0 star property
8.6 out of 10, Excellent, (705)
" Great place to stay "
The price is P4,556
P5,363 total
includes taxes & fees
Jul 30 - Jul 31
FOUND Hotel Carlton, Nob Hill

The Lodge at Tiburon

3.5 star property
8.8 out of 10, Excellent, (1011)
"Love staying at this hotel. Great location, staff and rooms"
The price is P10,553
P13,431 total
includes taxes & fees
Jul 20 - Jul 21
The Lodge at Tiburon

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2419)
"Very lovely hotel in a good location."
The price is P9,621
P13,930 total
includes taxes & fees
Jul 9 - Jul 10
Hotel Nikko San Francisco

Hotel Zephyr San Francisco

4.0 star property
8.6 out of 10, Excellent, (2063)
"Perfect location great hotel!"
The price is P7,406
P10,709 total
includes taxes & fees
Jul 9 - Jul 10
Hotel Zephyr San Francisco

Handlery Union Square Hotel

3.5 star property
8.8 out of 10, Excellent, (2497)
"Great stay! "
The price is P8,582
P10,101 total
includes taxes & fees
Jul 9 - Jul 10
Handlery Union Square Hotel

SFO El Rancho Inn SureStay Collection by Best Western

3.0 star property
8.4 out of 10, Very Good, (2799)
"Very friendly staff, great room, and exceptional breakfast"
The price is P6,153
P7,119 total
includes taxes & fees
Jul 14 - Jul 15
SFO El Rancho Inn SureStay Collection by Best Western

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1253)
"Great stay!"
The price is P8,690
P11,344 total
includes taxes & fees
Jul 13 - Jul 14
Hyatt Regency San Francisco Airport

InterContinental Mark Hopkins by IHG

4.0 star property
9.2 out of 10, Wonderful, (1033)
" Beautiful area, safe, beautiful stay!"
The price is P8,164
P11,742 total
includes taxes & fees
Jul 10 - Jul 11
InterContinental Mark Hopkins by IHG

Hotel Skye SFO

2.5 star property
8.8 out of 10, Excellent, (1330)
"Great staff, location, enjoyed the stay "
The price is P6,072
P7,292 total
includes taxes & fees
Jul 9 - Jul 10
Hotel Skye SFO

San Remo Hotel

2.0 star property
8.8 out of 10, Excellent, (1001)
"Great location, great price...European style...all good!"
San Remo Hotel

HYATT house Emeryville/San Francisco Bay Area

3.0 star property
9.0 out of 10, Wonderful, (1041)
"It's a good location."
The price is P10,100
P11,332 total
includes taxes & fees
Jul 13 - Jul 14
HYATT house Emeryville/San Francisco Bay Area

The Dylan at SFO

3.0 star property
9.0 out of 10, Wonderful, (1675)
"It’s a wonderful stay!"
The price is P6,351
P7,557 total
includes taxes & fees
Jul 13 - Jul 14
The Dylan at SFO

The Marina Inn on San Francisco Bay

2.5 star property
8.6 out of 10, Excellent, (1981)
"It is a great place to stay for vacation! "
The Marina Inn on San Francisco Bay

The Atrium Hotel

2.5 star property
8.6 out of 10, Excellent, (1003)
"Good easy reasonanly priced place to stay at, close to aitport"
The price is P5,914
P7,183 total
includes taxes & fees
Jul 13 - Jul 14
The Atrium Hotel

King George Hotel

3.0 star property
8.6 out of 10, Excellent, (1994)
"Great location and staff. We will definitely stay here again."
The price is P4,520
P6,166 total
includes taxes & fees
Jul 9 - Jul 10
King George Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Fisherman's Wharf map

Fisherman's Wharf

1 out of top 10 points of interest in this area

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

Union Square map

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco map

Downtown San Francisco

3 out of top 10 points of interest in this area

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market map

South of Market

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

Nob Hill map

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like Grace Cathedral and SF Masonic Auditorium.

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Airport Inn and Inn By The SFO.

How many hotels will I find in the Downtown South San Francisco area?

When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 14 Expedia hotels and other accommodations in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.

What can I see and do in this South San Francisco neighborhood?

See's Candies, Cinemark Century at Tanforan, and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.