Medical Center District

San Antonio

Photo by Linda Cronan
Photo by Linda Cronan

Popular places to visit

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

South Texas Medical Center

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

University Hospital - University Health System

Though University Hospital - University Health System might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University Hospital - University Health System

CHRISTUS Santa Rosa Hospital - Medical Center

Though CHRISTUS Santa Rosa Hospital - Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

CHRISTUS Santa Rosa Hospital - Medical Center

Methodist Healthcare

Though Methodist Healthcare might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

Methodist Healthcare

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

P2,094
per adult
92% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
SEA LIFE San Antonio

SEA LIFE San Antonio

P1,448
per adult
78% of travellers recommend
SEA LIFE San Antonio
San Antonio: Tower of the Americas Entry Ticket

San Antonio: Tower of the Americas Entry Ticket

P1,228
per adult
San Antonio: Tower of the Americas Entry Ticket
Best of San Antonio Tour

Best of San Antonio Tour

P9,539
per adult
94% of travellers recommend
Best of San Antonio Tour
San Antonio: San Antonio Zoo Any Day Ticket

San Antonio: San Antonio Zoo Any Day Ticket

P1,721
per adult
94% of travellers recommend
San Antonio: San Antonio Zoo Any Day Ticket
San Antonio: Witte Museum Admission Ticket

San Antonio: Witte Museum Admission Ticket

P989
per adult
74% of travellers recommend
San Antonio: Witte Museum Admission Ticket
See all activities in San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is P5,061 per night from Aug 22 to Aug 23
P5,061
P5,982 total
Aug 22 - Aug 23
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,872 reviews)
"It was good rooms and facility clean. I was however taken back by the $10 charge for parking. I don't think that fair."

Reviewed on Aug 15, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is P5,073 per night from Aug 31 to Sep 1
P5,073
P6,028 total
Aug 31 - Sep 1
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,001 reviews)
"A good place for a quick, one-night stay. I had to stay somewhere overnight for work-related reasons and chose this Marriot. Room was spacious. Bed was large and comfortable. The only drawback for me was the location is right at the intersection of Interstate 10 and loop 410. All of the roads you ..."

Reviewed on Aug 13, 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is P5,244 per night from Aug 31 to Sep 1
P5,244
P6,122 total
Aug 31 - Sep 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (983 reviews)
"Eveyrhing excelent the staff great they give us a great welcome and the hotel is in excellent condition"

Reviewed on Aug 18, 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is P5,586 per night from Aug 27 to Aug 28
P5,586
P6,603 total
Aug 27 - Aug 28
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,002 reviews)
"The stay was great overall. The only issue was the elevator was out."

Reviewed on Aug 14, 2025

Courtyard by Marriott Medical Center San Antonio
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza, San Antonio, TX
The price is P6,117 per night from Aug 21 to Aug 22
P6,117
P7,231 total
Aug 21 - Aug 22
includes taxes & fees
Stay at this 3.5-star historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our ...
9/10 Wonderful! (3,427 reviews)
Menger Hotel Great Review
"Great stay in a historic hotel that’s not just a hotel but a time capsule to the historic nature of the Alamo Area as well as Theodore Roosevelt’s Rough Riders along with other events like the time Babe Ruth came with the NY Yankees."

Reviewed on Aug 19, 2025

Menger Hotel
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is P7,253 per night from Aug 24 to Aug 25
P7,253
P8,573 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,645 reviews)
"Everything was great! Valet staff were super friendly and helpful and Donovan at the Front Desk was quite the gentleman, extremely nice and accommodating! The hotel was great! Room was very nice and comfortable! The breakfast, cocktails and food were a great bonus! Variety and quality were very nice! ..."

Reviewed on Aug 18, 2025

Drury Plaza Hotel San Antonio Riverwalk
See all 4,541 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

If you're looking for some top things to see and do in Northwest Los Angeles Heights and surrounding area, you can visit Alamo and Alamodome.

Northwest Los Angeles Heights
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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

If you're spending some time in Tobin Hill, San Antonio River and Temple Beth-El are top sights worth seeing.

Tobin Hill
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Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Uptown

Medical Center District