Medical Center District
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
P1,850
per adult
96% of travellers recommend
San Antonio Old Town Trolley Hop-on Hop-Off Tour
P3,380
per adult
92% of travellers recommend
San Antonio: Witte Museum Admission Ticket
P1,061
per adult
88% of travellers recommend
San Antonio CityPASS®: Save on admission to 4 must-see attractions
P3,931
per adult
96% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
P1,125
per adult
100% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is P5,557 per night from Oct 4 to Oct 5
P5,557
per night
Oct 4 - Oct 5
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,691 reviews)
"Room was clean and was nice. Property was dated and smelled musty. Breakfast coffee was cold."
Reviewed on Sep 29, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is P5,632 per night from Oct 13 to Oct 14
P5,632
per night
Oct 13 - Oct 14
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is P6,139 per night from Oct 8 to Oct 9
P6,139
per night
Oct 8 - Oct 9
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,002 reviews)
"Room had everything we needed and it was cleaned and organized. The beds were comfy and the AC worked great!"
Reviewed on Sep 30, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is P5,387 per night from Nov 1 to Nov 2
P5,387
per night
Nov 1 - Nov 2
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,170 reviews)
"It was OK. It was comfortable and clean and people were very kind. I will say that the air-conditioning unit was broken and it kept turning on full blast being very loud and rackety for 60 seconds and then completely shutting off it did that for hours and disturbed my sleep when it was maybe 4 o’clock ..."
Reviewed on Sep 27, 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is P9,925 per night from Oct 27 to Oct 28
P9,925
per night
Oct 27 - Oct 28
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (3,165 reviews)
"Arrived after ck in time by 1 1/2 and still had to wait 1/2hr to get in our room. We were exhausted and wanted to lay down."
Reviewed on Oct 1, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is P5,576 per night from Oct 27 to Oct 28
P5,576
per night
Oct 27 - Oct 28
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,454 reviews)
"Close to downtown and great customer service"
Reviewed on Oct 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
Downtown San Antonio
The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Alamodome while you're exploring the area.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Uptown Central
While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.
Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.
Stone Oak
Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
