Medical Center District

San Antonio

Photo by Linda Cronan


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is P5,197 per night from Nov 9 to Nov 10
P5,197
P6,143 total
Nov 9 - Nov 10
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,032 reviews)
Great hospitality and service.

Reviewed on Nov 3, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is P5,209 per night from Nov 15 to Nov 16
P5,209
P6,190 total
Nov 15 - Nov 16
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,027 reviews)
Yes

Reviewed on Nov 1, 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is P4,682 per night from Nov 17 to Nov 18
P4,682
P5,467 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,030 reviews)
Staff was helpful! Everything super clean and free breakfast was good

Reviewed on Nov 2, 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is P4,951 per night from Nov 16 to Nov 17
P4,951
P5,852 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,006 reviews)
Exellent Service, spotless room. Super satisfied!

Reviewed on Nov 4, 2025

Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St, San Antonio, TX
The price is P7,194 per night from Nov 19 to Nov 20
P7,194
P10,095 total
Nov 19 - Nov 20
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (2,123 reviews)
This hotel is one of my favorites but the 60 a night for parking was outrages.

Reviewed on Nov 3, 2025

Hotel Valencia Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street, San Antonio, TX
The price is P4,161 per night from Nov 16 to Nov 17
P4,161
P5,944 total
Nov 16 - Nov 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (3,714 reviews)
1 night stay did use these services. Wall electric plug next to A/C did not work. Hair dryer in bathroom did not work. Chair in room showed a lot of wear on the seat. Not a deal breaker.

Reviewed on Nov 3, 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
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Shearer Hills - Ridgeview

If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and San Pedro Driving Range & Par 3 Course are top sights worth seeing.

Shearer Hills - Ridgeview
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like Alamo and San Antonio Museum of Art.

Tobin Hill
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Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Uptown


Medical Center District