Medical Center District
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Old Town Trolley Hop-on Hop-Off Tour
P3,327
per adult
92% of travellers recommend
San Antonio: Six Flags Fiesta Texas Admission Ticket
P2,997
per adult
80% of travellers recommend
San Antonio: Witte Museum Admission Ticket
P1,046
per adult
84% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
P1,108
per adult
100% of travellers recommend
The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
P1,415
per adult
84% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is P5,435 per night from Aug 16 to Aug 17
P5,435
P6,425 total
Aug 16 - Aug 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,563 reviews)
"I stayed at the hotel on 8-7-2026 and the morning of 8-8-2026 my truck windows had been broken and several of other vehicles as well I was told I’ll receive a refund for the stay but haven’t received it"
Reviewed on Aug 14, 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is P5,151 per night from Aug 21 to Aug 22
P5,151
P6,089 total
Aug 21 - Aug 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,000 reviews)
"The friendly staff"
Reviewed on Aug 10, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is P5,508 per night from Aug 18 to Aug 19
P5,508
P6,511 total
Aug 18 - Aug 19
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,403 reviews)
"Nice Quiet place to stay clean. Very good service."
Reviewed on Aug 13, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is P6,161 per night from Sep 13 to Sep 14
P6,161
P7,321 total
Sep 13 - Sep 14
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,139 reviews)
"I stayed here three times in the past 3 months and it was excellent! The bar was great the only complaint I have is that it's not opened earlier. Food was excellent and it was very clean. We also took advantage of the pool which was great! Would definitely stay there again when I travel back to San ..."
Reviewed on Aug 13, 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is P7,852 per night from Aug 23 to Aug 24
P7,852
P9,281 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (5,070 reviews)
"Fantastic rooftop pool, beautiful room, great historical building, super helpful and friendly staff, great complimentary happy hour drinks and free breakfast, and great access to Riverwalk. Drury Plaza Riverwalk hotel is our new go to stay in San Antonio. Just wish the parking was more ..."
Reviewed on Aug 13, 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is P4,353 per night from Sep 7 to Sep 8
P4,353
P6,360 total
Sep 7 - Sep 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the breakfast ...
8/10 Very Good! (4,055 reviews)
"The ac wasn’t working the had to move us rooms and still problem with ac"
Reviewed on Aug 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
Downtown San Antonio
The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Alamodome while you're exploring the area.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
While visiting Uptown, you might make a stop by sights like Alamo Quarry Market and San Antonio Zoo and Aquarium.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
