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Medical Center District Hotels near San Antonio

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Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Medical Center District hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,540 reviews)
"Nice overnight stay."
United States
Sharon
The price is P5,665
P6,760 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites San Antonio Northwest Medical Center
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,780 reviews)
"Great place to stay"
United States
Gilbert
The price is P5,590
P6,670 total
includes taxes & fees
Nov 15 - Nov 16
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

3. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,116 reviews)
"The breakfast was good and staff was very helpful."
United States
Tina
The price is P5,917
P6,923 total
includes taxes & fees
Nov 25 - Nov 26
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A spacious lobby with a central staircase, seating area, and large windows.

4. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,203 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is P5,439
P6,524 total
includes taxes & fees
Dec 12 - Dec 13
San Antonio Marriott Northwest Medical Center
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Great property, nice rooms"
United States
Francisca
The price is P5,609
P6,693 total
includes taxes & fees
Nov 26 - Nov 27
Courtyard by Marriott Medical Center San Antonio
A modern kitchen with a large window, wooden counter, and two bar stools.

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,000 reviews)
"Went with my partner, away from the bustle but still close to everything. Great little place."
United States
Jaime
The price is P3,906
P4,570 total
includes taxes & fees
Dec 2 - Dec 3
Park Inn by Radisson, Medical Center
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (407 reviews)
"It was clean and cheap. I’d stay again but the mattress was old and you could hear and feel the springs sheets and room were clean."
United States
seth
The price is P3,210
P3,756 total
includes taxes & fees
Nov 13 - Nov 14
Studio 6 San Antonio, Tx - Northwest Medical Center
A modern bedroom with a large bed, bedside tables, a desk, and a chair.

8. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,005 reviews)
"Inexpensive. Above expectations. Quiet, cool, staff friendly."
United States
robert
The price is P2,899
P3,711 total
includes taxes & fees
Nov 13 - Nov 14
Motel 6 San Antonio, TX - Northwest Medical Center
A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

9. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (1,003 reviews)
"Good for a short stay traveling through the SA area."
United States
Jerron
The price is P3,147
P3,881 total
includes taxes & fees
Nov 15 - Nov 16
Studio 6 Extended Stay - San Antonio, TX - Medical Center
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

10. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (321 reviews)
"It’s. Nice place to stay, it’s big and comfortable."
United States
Jose Rolando
The price is P3,393
P3,970 total
includes taxes & fees
Nov 13 - Nov 14
Atria Inn & Suites
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

11. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (251 reviews)
"great place to stay close to the hospital. Would stay there again"
United States
Melanie
The price is P3,580
P4,547 total
includes taxes & fees
Nov 25 - Nov 26
OYO Inn & Suites Medical Center San Antonio
A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (580 reviews)
"Everything was just fine. 😁"
United States
Jennifer
The price is P2,770
P3,305 total
includes taxes & fees
Nov 25 - Nov 26
Flex Studios
A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,087 reviews)
"Loved the room and how clean the property was. Would stay here again."
United States
Muri
The price is P6,175
P7,446 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Place San Antonio-Northwest/Medical Center
A buffet with various food items, including omelets and other dishes, served in metal containers.

14. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
8.9 km from Medical Center District
9.4 out of 10, Exceptional, (1,011 reviews)
"The rooms were very clean and beds were so comfortable."
United States
Lori
The price is P6,358
P7,587 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express San Antonio-Airport by IHG
A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 9.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,408 reviews)
"Clean room, breakfast was great and filling. Hotel is super comfortable and easy city accesible."
United States
David
The price is P4,976
P5,938 total
includes taxes & fees
Nov 15 - Nov 16
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

16. Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
9 km from Medical Center District
9.4 out of 10, Exceptional, (2,336 reviews)
"Great stay"
United States
garry
The price is P7,175
P8,563 total
includes taxes & fees
Nov 22 - Nov 23
Drury Plaza Hotel San Antonio Airport
A modern hotel with a prominent sign reading "LA QUINTA".

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,172 reviews)
"Great stay for Lackland Air Force Base."
United States
Lakesha
The price is P6,546
P7,659 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
A modern kitchen with a central island, built-in appliances, and a coffee station.

18. Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown Central, 9.2 km from Medical Center District
8.6 out of 10, Excellent, (2,058 reviews)
"Good place to stay by the airport."
United States
Antonio
The price is P5,136
P6,130 total
includes taxes & fees
Nov 22 - Nov 23
Wyndham Garden San Antonio Airport
A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

19. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,615 reviews)
"Good budget business hotel."
United States
Vijay
The price is P4,187
P4,898 total
includes taxes & fees
Nov 22 - Nov 23
Best Western Medical Center North Inn & Suites Near Six Flags
A spacious dining area with multiple tables and chairs, a bar area, and a television mounted on the wall.

20. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.6 out of 10, Excellent, (1,008 reviews)
"Great place clean room good breakfast nice staff"
United States
Ioana
The price is P5,368
P6,527 total
includes taxes & fees
Nov 26 - Nov 27
Hampton Inn & Suites San Antonio Northwest/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,540 reviews
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,116 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,001 reviews
View
A spacious lobby with a central staircase, seating area, and large windows.
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,203 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,780 reviews
View

Hotels recommended for families in Medical Center District

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,540)
The price is P5,665
P6,760 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites San Antonio Northwest Medical Center

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Top Medical Center District Hotel Reviews

Omni La Mansion del Rio

Omni La Mansion del Rio

8/10 Good
"You can't beat the location, right in the middle of the best attractions on the Riverwalk. The staff is wonderful and helpful. Every staff member we encountered was very friendly. The rooms are clean and comfortable with a refrigerator and safe. Unfortunately, our refrigerator wasn't working. The showers are very good. The Riverwalk view rooms have a shared balcony which is great for people watching. The bar is a nice diversion after a day on the road. A short walk to restaurants and entertainment. Two Waymo stops outside the hotel and a parking garage across the street. You're a short walk to the Alamo and other attractions. The hotel restaurant is pricey and has selections like quail. Didn't eat there so can't really say good or bad. Valet was very expensive as well. Overall, it's a good place to stay, especially if you are there for the attractions or a function downtown."
Karl 3-night trip
Posted 3 hours ago
Omni La Mansion del Rio

Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.
What's a favorite place to stay in Medical Center District?
Based on our traveler data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Drury Inn & Suites San Antonio Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 124 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
What can I see and do in this San Antonio neighborhood?
Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

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