Medical Center District Hotels near San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,007 reviews)
"Perfect place to stay comfy and clean delicious food good staff thank you much."
United States
Iris Grisell
The price is P6,486
P7,706 total
includes taxes & fees
Apr 12 - Apr 13
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,291 reviews)
"Had a great stay. "
United States
MARY
The price is P5,449
P6,442 total
includes taxes & fees
Apr 5 - Apr 6
Drury Inn & Suites San Antonio Northwest Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,006 reviews)
"clean room staff was very friendly, breakfast was amazing!!"
United States
Drew
The price is P5,995
P6,999 total
includes taxes & fees
Apr 5 - Apr 6
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very Good, (3,244 reviews)
"Clean room, comfortable beds, awesome breakfast. The stay was great "
United States
VERNA
The price is P4,966
P5,870 total
includes taxes & fees
Apr 23 - Apr 24
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,003 reviews)
"Clean, helpful staff. "
United States
Edna
The price is P5,934
P7,015 total
includes taxes & fees
Apr 6 - Apr 7
Courtyard by Marriott Medical Center San Antonio

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,001 reviews)
"Great stay "
United States
Jody
The price is P3,876
P4,525 total
includes taxes & fees
Apr 27 - Apr 28
Park Inn by Radisson

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (229 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is P3,373
P4,362 total
includes taxes & fees
Apr 13 - Apr 14
OYO Inn & Suites Medical Center San Antonio

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (263 reviews)
"This Hotel is well lit and we felt safe. The staff was outstanding during check in and check out! Room was very clean. We had a very comfortable stay. "
United States
Gilbert
The price is P2,729
P3,186 total
includes taxes & fees
Mar 31 - Apr 1
Studio 6 San Antonio, Tx - Northwest Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (284 reviews)
"Yes .staff really nice "
United States
jamar
The price is P2,998
P3,500 total
includes taxes & fees
Apr 30 - May 1
Atria Inn & Suites

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (517 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is P2,562
P3,028 total
includes taxes & fees
Mar 31 - Apr 1
Flex Studios

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,002 reviews)
"Room was clean, beds comfortable, staff extremely friendly and helpful "
United States
Kathleen
The price is P2,876
P3,400 total
includes taxes & fees
Mar 31 - Apr 1
Motel 6 San Antonio, TX - Northwest Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (851 reviews)
"Good place to stay "
United States
fidel
The price is P2,573
P3,162 total
includes taxes & fees
Apr 7 - Apr 8
Studio 6 Extended Stay - San Antonio, TX - Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,004 reviews)
"A good hotel choice. Had a good breakfast. "
United States
Kelsey
The price is P3,706
P4,327 total
includes taxes & fees
Apr 19 - Apr 20
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (769 reviews)
"Really enjoying the peace of the hotel, and the location is amazing. "
United States
Abel
The price is P10,840
P14,721 total
includes taxes & fees
Apr 6 - Apr 7
Plaza San Antonio Hotel & Spa, Autograph Collection

Comfort Inn & Suites Texas Hill Country

Comfort Inn & Suites Texas Hill Country
2.5 star property
33.8 km from Medical Center District
8.6 out of 10, Excellent, (1,000 reviews)
"The rooms were clean, everything was well maintained, breakfast was great and the location of the hotel was perfect."
United States
Stephen
The price is P5,633
P6,365 total
includes taxes & fees
Apr 20 - Apr 21
Comfort Inn & Suites Texas Hill Country

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,540 reviews)
"Great place"
United States
Jonatan
The price is P5,982
P9,573 total
includes taxes & fees
Apr 27 - Apr 28
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.0 out of 10, Wonderful, (239 reviews)
"The room was very clean and staff was great"
United States
Eda
The price is P5,994
P6,894 total
includes taxes & fees
Mar 31 - Apr 1
Extended Stay America Premier Suites - San Antonio - Schertz

Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (863 reviews)
"The room was clean and affordable "
United States
Tamara
The price is P5,084
P5,847 total
includes taxes & fees
Apr 6 - Apr 7
Hampton Inn & Suites Schertz

Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
8.8 out of 10, Excellent, (339 reviews)
"Very basic clean hotel nice for overnight stay."
United States
Syed
The price is P4,171
P4,494 total
includes taxes & fees
Apr 20 - Apr 21
Spark by Hilton San Antonio Dominion

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very Good, (1,002 reviews)
"Friendly Staff, easily find location,"
United States
Hua
The price is P4,375
P5,107 total
includes taxes & fees
Apr 13 - Apr 14
Best Western Garden Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,006 reviews
View
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,291 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,007 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,003 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very Good
3,244 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighborhood.
What's a favorite place to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 119 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
What can I see and do in this San Antonio neighborhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute, and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

Explore a world of travel with Expedia