Medical Center District

San Antonio

River walk in San Antonio
River walk in San Antonio
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Medical Center District

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is P5,232 per night from Feb 7 to Feb 8
P5,232
P6,184 total
Feb 7 - Feb 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,195 reviews)
Clean room but the hotel is outdated

Reviewed on Jan 31, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is P5,959 per night from Feb 21 to Feb 22
P5,959
P7,081 total
Feb 21 - Feb 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,003 reviews)
clean room; courteous staff at front desk & dining room

Reviewed on Feb 2, 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
The price is P3,763 per night from Mar 1 to Mar 2
P3,763
P4,394 total
Mar 1 - Mar 2
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,001 reviews)
The a/c kept the room nice and warm.

Reviewed on Jan 23, 2026

Park Inn by Radisson
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is P7,607 per night from Feb 15 to Feb 16
P7,607
P10,677 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,428 reviews)
Great place, room was very clean, place was super nice, walking distance to everything 💪

Reviewed on Feb 1, 2026

Hotel Valencia Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is P6,369 per night from Feb 15 to Feb 16
P6,369
P7,529 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (3,765 reviews)
Beautiful hotel with great history. Was a bit cold due to crazy cold weather. Staff was excellent!

Reviewed on Jan 31, 2026

Menger Hotel
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
9700 West Military Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is P4,458 per night from Feb 10 to Feb 11
P4,458
P7,706 total
Feb 10 - Feb 11
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,421 reviews)
Very friendly staff

Reviewed on Jan 31, 2026

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
Sam's Burger Joint

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
One of the coolest bars in San Antonio. Definitely check it out.

Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Zoo and Aquarium and San Antonio Museum of Art.

Tobin Hill
Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Uptown
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Alamo Heights

You'll enjoy the museums and coffeehouses in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District