Medical Center District
San Antonio
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Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is P5,448 per night from Jun 25 to Jun 26
P5,448
P6,440 total
Jun 25 - Jun 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,431 reviews)
"Our favorite Quinta, where family can enjoy vacation."
Reviewed on Jun 24, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is P6,206 per night from Jul 24 to Jul 25
P6,206
P7,375 total
Jul 24 - Jul 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,090 reviews)
"Todo excelente gracias"
Reviewed on Jun 24, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is P5,521 per night from Jul 5 to Jul 6
P5,521
P6,527 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,356 reviews)
"Great place and family friendly"
Reviewed on Jun 23, 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is P5,461 per night from Jul 10 to Jul 11
P5,461
P6,455 total
Jul 10 - Jul 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is P8,466 per night from Jun 30 to Jul 1
P8,466
P10,008 total
Jun 30 - Jul 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,790 reviews)
"Great buffet breakfast included; the staff were courteous and helpful"
Reviewed on Jun 24, 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is P4,362 per night from Jul 5 to Jul 6
P4,362
P6,375 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the breakfast ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
Downtown San Antonio
The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by San Antonio River or Alamodome while you're exploring the area.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and San Antonio River.
Stone Oak
Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Stone Creek Village and Stone Ridge Market while you're in town.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
