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Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Room was clean and ready for our stay. Breakfast was good and staff very friendly from the moment we walked in to check in. The bed was a little in the stiff side but that won’t stop me from coming back again. I really like the area and the ease to get to dining and shopping options.
Reviewed on Dec 21, 2025

San Antonio Marriott Northwest Medical Center
Best hotel!
Reviewed on Dec 15, 2025

Courtyard by Marriott Medical Center San Antonio
Excellent service and very clean rooms
Reviewed on Dec 15, 2025

Hotel Valencia Riverwalk
This place is absolutely gorgeous!
Reviewed on Dec 20, 2025

Riverwalk Plaza
Great staff and so convenient!
Reviewed on Dec 21, 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Had a great stay- they were very accommodating with my two dogs and had a great breakfast Buffett! The room was clean and the staff was very helpful and attentive whenever I needed! I would definitely stay here again!
Reviewed on Dec 15, 2025
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Other neighbourhoods around Medical Center District

Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Shearer Hills - Ridgeview
If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and San Pedro Driving Range & Par 3 Course are top sights worth seeing.

Midtown
Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Tobin Hill
Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Museum of Art and Historic Brackenridge Golf Course.

Uptown
While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

