A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Luxury Hotels in Panama City, Panamá Province

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Check availability on Panama City Luxury Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Panama City luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
P22,034
P24,238 total
includes taxes & fees
Nov 3 - Nov 4
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.
A terrace with seating and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

2. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
P17,527
P19,280 total
includes taxes & fees
Oct 31 - Nov 1
JW Marriott Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A modern bar area with seating and a view of the city.
A modern interior with a spiral staircase, a large window, and a seating area.

3. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
P15,634
P17,198 total
includes taxes & fees
Nov 6 - Nov 7
Hilton Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.

4. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
P16,452
P18,098 total
includes taxes & fees
Oct 31 - Nov 1
Waldorf Astoria Panama
A restaurant with multiple dining tables, chairs, and a central water feature.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A bar area with multiple seating options, a bar counter, and a fireplace.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

5. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
P16,488
P18,137 total
includes taxes & fees
Oct 9 - Oct 10
Hotel La Compañía Casco Antiguo
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.

6. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
P8,283
P9,112 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Riu Plaza Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern building with a sign reading 'HYATT REGENCY.'
A modern interior with a central seating area, potted plants, and a staircase.
A spacious hotel lobby with modern furniture, large windows, and a city view.

7. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
P11,714
P12,885 total
includes taxes & fees
Oct 18 - Oct 19
Hyatt Regency Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A high-rise building with a rooftop pool area, surrounded by other buildings.

8. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
P14,482
P15,931 total
includes taxes & fees
Nov 1 - Nov 2
W Panama
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop pool area with purple lounge chairs and a city skyline in the background.

9. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
  • Experience luxury and elegance in a Panamanian retreat with 2 restaurants, a spa, and casino.
P8,720
P8,720 total
includes taxes & fees
Oct 21 - Oct 22
Megapolis Hotel Panamá
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

10. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
  • Art deco elegance meets modern luxury in this Panama City hotel featuring 2 bars, a full-service spa, and an outdoor pool.
P13,258
P14,584 total
includes taxes & fees
Oct 18 - Oct 19
Bristol Panama, a Registry Collection Hotel
View all properties

Top Panama City Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"Todo salio increíble"
Ana Ligia 2-night trip
Posted less than an hour ago
Courtyard by Marriott Panama Multiplaza Mall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Breakfast is excellent. Property is on the city center. Nice view"
Ariel 6-night trip
Posted 5 hours ago
Hotel Riu Plaza Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Bueno"
Enimer 5-night trip
Posted 8 hours ago
Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

10/10 Excellent
"Muy buena ubicación, habitaciones limpias y espaciosas. Bar abierto hasta las 11pm"
Manuel 1-night trip
Posted 1 day ago
Las Americas Golden Tower Panama
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Our stay at the JW Marriott Panama was absolutely wonderful. The hotel itself is stunning—beautifully designed, elegant, and with incredible views of the ocean and Panama City skyline. The amenities really make the property feel like a luxury resort, especially the beautiful pools, restaurants, fitness center, and relaxing outdoor spaces. What truly stood out, though, was the outstanding service. From the moment we arrived, the staff was welcoming, professional, and attentive. I especially want to recognize Sumaya, who made our check-in experience phenomenal. She was incredibly warm, helpful, and made us feel genuinely welcomed from the very beginning. The combination of a beautiful property, excellent amenities, and exceptional hospitality made our stay truly memorable. We would absolutely recommend the JW Marriott Panama and look forward to coming back!"
Alejandro 2-night trip
Posted 1 day ago
JW Marriott Panama
Hotel Ojos del Rio

Hotel Ojos del Rio

8/10 Good
"No hot water in the shower."
charles 2-night trip
Posted 7 days ago
Hotel Ojos del Rio

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Avenida Balboa.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina Station, and Santo Tomás Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.