Panama City Trips (flight + hotel)

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
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Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or National Theater while you're exploring the area.

Find hotel + flight trips in Casco Viejo

Top hotels in Panama City

Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundable
The price is P4,822 per night from 12 May to 13 May
P4,822
per night
12 May - 13 May
8.4/10 Very Good! (1,005 reviews)
"Such a comfy hotel!!"

Reviewed on Apr 25, 2024

Decapolis Hotel Panama City
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is P5,817 per night from 30 Apr to 1 May
P5,817
per night
30 Apr - 1 May
9/10 Wonderful! (2,317 reviews)
"nice"

Reviewed on Apr 26, 2024

Hotel Riu Plaza Panama
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Fully refundable
The price is P8,630 per night from 12 May to 13 May
P8,630
per night
12 May - 13 May
8.2/10 Very Good! (390 reviews)
"The staff was friendly and very helpful. The hotel was clean and great ambiance."

Reviewed on Apr 26, 2024

Megapolis Hotel Panamá
See all 1,128 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama City vacation package cost?
Our Panama City packages, which start from just , are an easy way to save. All you have to do is choose your favorite hotels, flights and rental car to create your ideal getaway.
How do I get a cheap travel package to Panama City?
Find flights that fit your schedule, add a hotel room to your booking and watch how much you save with a Panama City vacation package. It’s as simple as that! From flights and hotels to tours and rental cars, Expedia makes traveling on a budget easy. And with over 550 partner airlines and 1,000,000 hotels all over the world to select from, you’ll never be short of choice.
Where should I stay in Panama City?
If it’s your first visit to Panama City, we’d recommend Casco Viejo. This well-known neighborbood is where you’ll find some big attractions, such as Metropolitan Cathedral of Panama.
What are the top hotels in Panama City?
Travelers heading to Panama City often book a room at Hotel Riu Plaza Panama or Novotel Panama City. These options are in Bella Vista. Another great neighborhood is Casco Viejo. Novotel Panama City and Principe Hotel and Suites are reputable choices in this area.
How far in advance should I book my Panama City vacation?
While not all air carriers release tickets early, you can normally start comparing international flights on Expedia up to 12 months in advance. This is the time when you’ll nab some fantastic deals. If you’re booking last minute, you might still be in luck. Discounted prices occasionally appear a few weeks before departure.
What does an Expedia Panama City travel package include?
It all boils down to what kind of getaway you have in mind. Panama City vacation deals can include flights, car rentals and hotels. You can mix and match to create the bundle that suits your needs. You can also add on experiences and activities after you’ve booked to get even bigger discounts.
What should I know before booking a Panama City travel package?
Bundling your bookings into a Panama City vacation package is the most convenient way to organize your trip. Not only that, you’ll get great discounts just for combining your flights, hotels and car rentals. Once you’ve booked, why not add on a day tour or an activity?
Can I choose my airline with a Panama City Expedia vacation package?
Definitely. Expedia has over 550 airline partners to choose from around the world. With so much choice, finding the ideal carrier to get you to Panama City won’t be difficult.
If I'm not able to travel, can I cancel my Panama City vacation package?
We get that life doesn’t always go according to plan. If you’ve locked in a Panama City vacation package and have to amend or cancel it, we can help. It’s always worth having a look at our Customer Service Portal first for information. But generally speaking, if you’ve taken out your package in the last 24 hours, you may be able to amend or cancel your itinerary for free. If it’s been longer than 24 hours, your airline, hotel or car rental company may charge a fee.

Popular places to visit

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Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
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Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
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Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa

What to do in Panama City

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Half day of Panama city and canal Tour

P3,689
Per adult
100% of travellers recommend
Half day of Panama city and canal Tour
Image for Ocean to Ocean Panama Canal and Jungle Tour

Ocean to Ocean Panama Canal and Jungle Tour

P7,469
Per adult
96% of travellers recommend
Ocean to Ocean Panama Canal and Jungle Tour
Image for Day Tour in San Blas Islands All Included Visiting 4 Islands

Day Tour in San Blas Islands All Included Visiting 4 Islands

P8,797
Per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
See all activities in Panama City

More trip options

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.