Hotels near Medi Center

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Dec 26 - Dec 27
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Our top choices for Medi Center hotels

Free daily continental breakfast
Quality Inn San Diego I-5 Naval Base

Quality Inn San Diego I-5 Naval Base

Quality Inn San Diego I-5 Naval Base
2.5 star property
3.2 km from Medi Center
7.8 out of 10, Good, (877)
"Everything was really fine!"
United States
Sebastian Alejandro
The price is P5,506
P6,219 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn San Diego I-5 Naval Base
Desk, blackout drapes, iron/ironing board, free WiFi
Lodge at 32nd

Lodge at 32nd

Lodge at 32nd
2.5 star property
1.8 km from Medi Center
7.6 out of 10, Good, (801)
"Great place for the money "
United States
Isabel
The price is P4,375
P5,595 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Lodge at 32nd
Memory foam beds, blackout drapes, iron/ironing board, free WiFi
Stay Classy Hostel

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 4.2 km from Medi Center
9.6 out of 10, Exceptional, (788)
"Good place to stay "
United States
sai
Stay Classy Hostel
View from room
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
4.9 km from Medi Center
9.4 out of 10, Exceptional, (1001)
"Room was spacious! Best hotel I’ve ever been to! "
United States
Liyah
The price is P7,929
P9,193 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Marriott Vacation Club®, San Diego
Beach nearby, beach umbrellas, beach towels
1906 Lodge

1906 Lodge

1906 Lodge
3.5 star property
7.3 km from Medi Center
9.8 out of 10, Exceptional, (885)
"Excellent staff, great perks and terrific location."
United States
Gary
The price is P14,624
P16,115 total
includes taxes & fees
Jan 8 - Jan 9, 2026
1906 Lodge
Premium bedding, pillowtop beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is P5,771
P8,391 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Restaurant
Crown City Inn

Crown City Inn

Crown City Inn
2.5 star property
6.9 km from Medi Center
9.6 out of 10, Exceptional, (660)
"Great location, very clean room, had everything we needed. Would definitely stay again!"
United States
Cheryl
Crown City Inn
Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
6.7 km from Medi Center
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Premium bedding, pillowtop beds, desk, laptop workspace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 4.6 km from Medi Center
9.2 out of 10, Wonderful, (608)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is P6,440
P9,169 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sentral Gaslamp Quarter
Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
5.8 km from Medi Center
9.4 out of 10, Exceptional, (1358)
"Amazing hotel, great staff and awesome food!"
United States
michael
The price is P13,450
P15,434 total
includes taxes & fees
Dec 30 - Dec 31
Lafayette Hotel & Club
Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
5.7 km from Medi Center
9.2 out of 10, Wonderful, (3581)
"Room was clean, staff was friendly and helpful."
United States
Maria
The price is P6,301
P6,943 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Plus Marina Gateway Hotel
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.2 out of 10, Wonderful, (2055)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is P11,433
P15,911 total
includes taxes & fees
Dec 28 - Dec 29
Omni San Diego Hotel at the Ballpark
Exterior
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 5.1 km from Medi Center
9.2 out of 10, Wonderful, (630)
"Great stay"
United States
Angelica
The price is P9,338
P10,827 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Shared kitchen facilities
Gaslamp Hostel

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 5.1 km from Medi Center
9.2 out of 10, Wonderful, (539)
"Great location with clean, comfortable rooms. Amazing ambiance and professional staff. I would stay hear again."
United States
Anthony Michael
Gaslamp Hostel
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 5.5 km from Medi Center
9.2 out of 10, Wonderful, (1955)
"Best place to stay with family in San diego"
United States
vishakha
The price is P10,278
P15,004 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Marriott Marquis San Diego Marina
3 restaurants, breakfast, lunch, dinner served; seafood
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.2 out of 10, Wonderful, (1003)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is P16,151
P21,813 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Pendry San Diego
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (3163)
"Beautiful hotel"
United States
Jordan M.
The price is P10,006
P14,306 total
includes taxes & fees
Dec 28 - Dec 29
Hard Rock Hotel San Diego
Meeting facility
Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
6.1 km from Medi Center
9.2 out of 10, Wonderful, (1000)
"Great place to stay"
United States
Kimberly
The price is P11,042
P12,829 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Springhill Suites San Diego Downtown/Bayfront
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (1237)
"Clean, courteous staff, good location. "
United States
Carla
The price is P5,349
P6,202 total
includes taxes & fees
Dec 28 - Dec 29
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (1017)
"Great hotel, excellent location, excellent view on rooftop!"
United States
Rajeev
The price is P6,930
P7,883 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Gaslamp Plaza Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Medi Center Hotel Reviews

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

10/10 Excellent
"It's a great place to visit and share time with friends and family. "
Bertha 2-night trip
Posted 3 days ago
Marriott Marquis San Diego Marina

Hotels near other Medi Center attractions

Nu-Way Christian Ministries

Find out about the history of San Diego when you take a trip to Nu-Way Christian Ministries.
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Pilgrim Progressive Baptist Church

Pilgrim Progressive Baptist Church is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels?
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Frequently asked questions

What's the area like around Medi Center?
Medi Center is located in San Diego. If you're looking for a convenient place to stay, check out the 26 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Medi Center?
Lodge at 32nd is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and a snack bar/deli. It's located 1.1 mi (1.8 km) from Medi Center. Other good options within a few miles include Good Life Vacation Rental Resort and Hard Rock Hotel San Diego.
How many hotels will I be able to find near Medi Center?
Expedia has 26 hotels and other accommodations within a mile from Medi Center.
If I need to cancel the hotel reservation for my stay near Medi Center, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals available near Medi Center.
What can I see and do near Medi Center?
San Diego Natural History Museum, San Diego Museum of Art, and San Diego Air and Space Museum feature a variety of fascinating exhibits to see while you're in town. Hotel del Coronado, California Tower, and Star of India are some of the notable landmarks to see in the area. You can watch performances at Old Globe Theater, San Diego Civic Theatre, and The Rady Shell at Jacobs Park if you're interested in local theater.