Hotels near Mayo Clinic Florida

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (489 reviews)
"Good breakfast "
United States
Vashti
The price is P8,415
P9,551 total
includes taxes & fees
May 1 - May 2
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (211 reviews)
"It was a very nice hotel , would recommend for any one 👌 "
United States
Michael
The price is P9,910
P11,248 total
includes taxes & fees
May 8 - May 9
Hilton Jacksonville At Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
"Great stay and breakfast "
United States
Lindsay
The price is P7,420
P8,422 total
includes taxes & fees
May 10 - May 11
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay!"
United States
Satavia
The price is P6,025
P6,838 total
includes taxes & fees
May 3 - May 4
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (772 reviews)
"Enjoyed our stay"
United States
Alan
The price is P9,778
P11,098 total
includes taxes & fees
May 9 - May 10
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (554 reviews)
"First time and loved it! "
United States
Shaina
The price is P9,778
P11,098 total
includes taxes & fees
May 17 - May 18
Element Jacksonville Beach

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (464 reviews)
"Loved this property. Perfect getaway and will definitely return."
United States
Diona
The price is P10,968
P12,449 total
includes taxes & fees
Apr 28 - Apr 29
The Hotel Palms Poolside

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,003 reviews)
"Good clean place to stay"
United States
Daniel
The price is P7,713
P8,755 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express Jacksonville Beach by IHG

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,076 reviews)
"Great place to stay"
United States
Jeffrey
The price is P8,208
P9,316 total
includes taxes & fees
May 25 - May 26
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (295 reviews)
"Staff was super friendly and room was spotless. "
United States
Carla
The price is P12,190
P13,836 total
includes taxes & fees
Apr 28 - Apr 29
The Hotel Palms Courtyard

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (821 reviews)
"clean"
United States
Adam
The price is P36,379
P42,324 total
includes taxes & fees
May 10 - May 11
Ponte Vedra Inn & Club

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,881 reviews)
"We loved this stay- it was relaxed and fun!"
United States
Amy
The price is P10,331
P11,726 total
includes taxes & fees
May 3 - May 4
Margaritaville Jacksonville Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,007 reviews)
"Very convenient to the beach and short walk to restaurants. "
United States
Michelle
The price is P9,085
P10,312 total
includes taxes & fees
May 4 - May 5
Best Western Oceanfront

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Perfect location to the beach and clean room"
United States
Caulan
The price is P12,854
P14,589 total
includes taxes & fees
May 17 - May 18
Four Points by Sheraton Jacksonville Beachfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (674 reviews)
"Breakfast was fantastic loved how big the rooms were "
United States
Jonatan
The price is P12,329
P13,993 total
includes taxes & fees
May 11 - May 12
Springhill Suites By Marriott Jacksonville Beach Oceanfront

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (190 reviews)
"A bit dirty. Floor wasn’t clean. Bed sheets had hair, and pillow cases some dark stains. Blood stains on the shower. It’s a nice hotel, nice location, I wish they did a better job with cleaning. And it would be nice if the breakfast was included."
United States
Oleksandr
The price is P12,338
P14,004 total
includes taxes & fees
May 10 - May 11
AC Hotel Jacksonville St Johns Town Center

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,003 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is P8,516
P9,495 total
includes taxes & fees
May 10 - May 11
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,001 reviews)
"Great place to stay"
United States
Clyde
The price is P7,531
P8,548 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,683 reviews)
"Staff were very friendly, breakfast was good and outdoor pool area was excellent "
United States
Dawn
The price is P9,910
P11,248 total
includes taxes & fees
May 21 - May 22
Hampton Inn Jacksonville Beach/Oceanfront

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (99 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
The price is P8,138
P9,237 total
includes taxes & fees
May 3 - May 4
TownePlace Suites by Marriott® Jacksonville Mayport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
489 reviews
View
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
211 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,003 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.8
Excellent
1,003 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very Good
772 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Hotels near other Mayo Clinic Florida attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 49 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea, and SeaWalk Pavillion. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.