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Hotels near Mayo Clinic Florida

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Sep 10 - Sep 11
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Sep 11 - Sep 12
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Our top choices for Mayo Clinic Florida hotels

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
A multi-story hotel with a central entrance, surrounded by well-maintained lawns and palm trees.
A modern kitchen with a bar area, seating, and a view of the outdoors.
An outdoor patio area with seating and a central fire feature, surrounded by buildings and palm trees.

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
1.1 km from Mayo Clinic Florida
United States
Michaelanne
P8,563
P9,719 total
includes taxes & fees
Oct 2 - Oct 3
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
A modern restaurant with a bar area, wooden ceiling, and large windows.
A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.
A covered outdoor seating area with chairs and sofas, a fountain, and a view of a lake and trees.
A modern lobby with a curved sofa, round coffee tables, and a large pillar.

2. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
0.8 km from Mayo Clinic Florida
United States
Kristen
P9,743
P11,059 total
includes taxes & fees
Sep 20 - Sep 21
Hilton Jacksonville at Mayo Clinic near Beaches
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
A hotel room with a bed, a sofa, a nightstand, and a wall-mounted lamp.
An outdoor patio with a pool, wooden pergola, and seating area.
A multi-story hotel with a modern design, featuring a covered outdoor area with seating and a fire pit.

3. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
United States
Tiffany
P7,440
P8,444 total
includes taxes & fees
Oct 4 - Oct 5
TownePlace Suites by Marriott Jacksonville East
A hotel lobby with a bar area, seating arrangements, and a reception desk.
A hotel room with a bed, a desk, a sofa, and a small table. There is a mirror, a lamp, and a picture on the wall.
A gym with treadmills, elliptical machines, a bench press, and a rack of dumbbells.
An outdoor patio with a brick wall, a round table with striped chairs, and two large umbrellas.

4. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
United States
Patsy
P6,844
P7,768 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
A lobby with a reception desk, seating area, and a staircase.
A modern hotel room with a large bed, a blue sofa, a small table, and a wall-mounted lamp.
A modern kitchen with a refrigerator, coffee machine, and a bakery display.
An indoor swimming pool with clear views of trees outside, a tiled floor, and a covered seating area.

5. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.6 km from Mayo Clinic Florida
United States
Sam
P6,439
P7,309 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
An outdoor seating area with stone fire pit, wicker furniture, and potted plants.
A bar area with a long counter, multiple stools, and shelves stocked with bottles.
A hotel pool area with lounge chairs and umbrellas, surrounded by multi-story buildings with balconies.
A modern hotel lobby with a flat-screen TV, a fireplace, comfortable seating, and a coffee bar.

6. Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
0.4 km from Mayo Clinic Florida
United States
Troy
P9,503
P10,786 total
includes taxes & fees
Oct 10 - Oct 11
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
A backyard with a swimming pool, wooden deck, and outdoor furniture.
A hotel room with two beds, a floral wallpaper, a ceiling light, and a wall-mounted air conditioner.
A wooden fence with a blue and white striped umbrella, two green lounge chairs, and a white chair.
A compact kitchen with a refrigerator, microwave, and a dining area with a table and chairs.

7. Hotel Palms

Hotel Palms
7.8 km from Mayo Clinic Florida
United States
Vinny
P8,883
P10,082 total
includes taxes & fees
Sep 13 - Sep 14
Hotel Palms
A multi-story hotel with a modern design, featuring a covered entrance and a parking area with handicapped accessibility.
A hotel room with two beds, a desk, a chair, and a large window with a view.
A breakfast bar with a digital menu display, various food dispensers, and a yogurt machine.
A coastal cityscape with a long beach, a large hotel with a curved facade, and a clear sky.

8. Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Southside, 7.7 km from Mayo Clinic Florida
United States
Ian
P8,581
P9,739 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.
A pathway leading to a sunset over a beach with sand and grass.
A modern hotel lobby with a long reception desk, seating area, and large windows.
A modern conference room with a long table, several chairs, and pendant lighting.

9. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
5.4 km from Mayo Clinic Florida
United States
Nick
P9,503
P10,786 total
includes taxes & fees
Oct 11 - Oct 12
Element by Marriott Jacksonville Beach
An outdoor patio area with seating, a fire pit, and a barbecue grill.
A modern kitchen with wooden cabinets, a central island with jars, and a countertop with toasters.
A modern living room with sofas, a coffee table, and a dining area.
A modern hotel with a sign reading "Towneplace Suites by Marriott" and a parking lot in front.

10. TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
10.8 km from Mayo Clinic Florida
United States
irina
P6,877
P7,805 total
includes taxes & fees
Sep 20 - Sep 21
TownePlace Suites by Marriott® Jacksonville Mayport
A laptop on a wooden desk with a white mug, a spoon, and a smartphone.
A kitchen counter with a coffee maker, a blender, a book titled 'CHECKERS,' and a water bottle.

11. Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
Deerwood, 7.8 km from Mayo Clinic Florida
United States
Michele
P6,855
P7,781 total
includes taxes & fees
Oct 3 - Oct 4
Hyatt Studios Jacksonville/St Johns Town Center
A spacious lobby with a central seating area, large windows, and a fountain.
A hotel room with two beds, a desk, a chair, a TV, and a view of the ocean.
A beach umbrella with two chairs underneath, a sandy beach, and the ocean in the background.
A spacious lobby with high ceilings, wooden beams, and a central chandelier.

12. Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
6.3 km from Mayo Clinic Florida
United Kingdom
Michael
P31,196
P36,806 total
includes taxes & fees
Sep 13 - Sep 14
Ponte Vedra Inn & Club
A spacious lobby with a reception desk, seating area, and large windows.
A modern coffee shop interior with a central counter, shelves stocked with snacks, and a refrigerated section labeled 'FROZEN' and 'CHILLED'.
A bar area with wooden chairs, a round table, and a brick wall.
An indoor dining area with tables and chairs, a ceiling fan, and a view of the outdoors.

13. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
8.5 km from Mayo Clinic Florida
United States
Brooke
P8,121
P9,055 total
includes taxes & fees
Sep 24 - Sep 25
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
A modern bar area with a central island, multiple seating options, and a variety of bottles displayed on shelves.
An outdoor seating area with white furniture and a well-maintained lawn, surrounded by large windows and a modern building facade.
A modern hotel with a pool, palm trees, and a clear blue sky.
A modern bar area with seating, a bar counter, and a view of the city through large windows.

14. AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
Southside, 8.1 km from Mayo Clinic Florida
United States
Alysha
P13,066
P14,830 total
includes taxes & fees
Sep 24 - Sep 25
AC Hotel Jacksonville St Johns Town Center
An outdoor seating area with a fire feature, chairs, and a table.
A modern bar area with a counter, bar stools, and a television screen.
A modern hotel room with two beds, a flat-screen TV, a desk, and a large window with a view of a building.
A modern bar area with a curved counter, multiple bar stools, and a variety of liquor bottles.

15. Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
Southside, 10.8 km from Mayo Clinic Florida
United States
Carol
P7,892
P8,957 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Indigo Jacksonville-Deerwood Park by IHG
A pool with a waterfall feature, surrounded by large rock formations.
A beachfront hotel with multiple balconies, a sandy beach, and ocean views.
A bar with a tiled roof, outdoor seating, and a view of the ocean.
A hotel with a pool, a parking lot, and a view of the ocean.

16. Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
6.3 km from Mayo Clinic Florida
United States
Susan
P10,362
P11,761 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Jacksonville Beach/Oceanfront
A spacious lobby with a glass floor, a reception desk, and a view of the ocean.
A bar area with a view of the beach, wooden bar stools, and a counter with a menu display.
A multi-story hotel with a beach view, parking lot, and a nearby restaurant.
A cafe with a tropical mural, a coffee menu, and a variety of seating options.

17. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
5.9 km from Mayo Clinic Florida
United States
Melissa
P9,331
P10,590 total
includes taxes & fees
Sep 15 - Sep 16
Margaritaville Jacksonville Beach
A hotel room with two beds, a desk with a computer, a chair, and a colorful carpet.
A hotel room with a microwave, coffee maker, and refrigerator on the counter. There is a door with a sign and a towel rack visible.
A golf course with a water hazard and a bridge.
A pier extending into the ocean at sunset with birds flying above.

18. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
4.6 km from Mayo Clinic Florida
United States
Jose
P7,266
P8,247 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express Jacksonville Beach by IHG
An outdoor patio with seating, a fire pit, and string lights.
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a fence.
A modern bar area with a counter, bar stools, and a television screen. There are round tables with chairs in the dining area.
A multi-story hotel with a modern design, featuring a large number of windows and a flat roof.

19. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
Southside, 8.6 km from Mayo Clinic Florida
United States
Gary
P7,952
P9,026 total
includes taxes & fees
Sep 13 - Sep 14
Hyatt Place Jacksonville / St. Johns Town Center
A self-service beverage station with a refrigerated display and a coffee machine.
A modern hotel reception area with a curved wooden reception desk, a digital display, and a view of the lobby.
A snack display in a store with various chips and snacks.
A modern lounge area with seating, tables, and hanging lights.

20. Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
Southside, 8.7 km from Mayo Clinic Florida
United States
Jennifer
P6,844
P7,768 total
includes taxes & fees
Sep 13 - Sep 14
Tru By Hilton Jacksonville St Johns Town Center
View all properties

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
9.6
Exceptional
594 reviews
View
A modern restaurant with a bar area, wooden ceiling, and large windows.
Hilton Jacksonville at Mayo Clinic near Beaches
9.4
Exceptional
352 reviews
View
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
TownePlace Suites by Marriott Jacksonville East
9.2
Wonderful
657 reviews
View
A hotel lobby with a bar area, seating arrangements, and a reception desk.
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
9.0
Wonderful
1,000 reviews
View
A lobby with a reception desk, seating area, and a staircase.
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
9.0
Wonderful
1,014 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

10/10 Excellent
"Staff was kind and very helpful. The property sits right off of the interstate.However, it was tucked away in the back.And we never heard the interstate or the busy road , we were on. Check in and check out was a breeze and the housekeeping staff rocks."
Patricia 2-night trip
Posted 15 hours ago
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

10/10 Excellent
"Everything was great, clean room, great staff and Wi-Fi, breakfast was great too,"
Christopher L 4-night trip
Posted 17 hours ago
Holiday Inn Express Jacksonville Beach by IHG
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

10/10 Excellent
"Everything was great except the breakfast could be better."
Donna 2-night trip
Posted 19 hours ago
TownePlace Suites by Marriott Jacksonville East
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

10/10 Excellent
"Great location"
Cynthia 2-night trip
Posted 2 days ago
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

10/10 Excellent
"Great service all around. The bus driver to the clinic was awesome!!’n"
Debbie 2-night trip
Posted 9 days ago
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 45 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville at Mayo Clinic near Beaches and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 45 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at Wilson Center For the Arts, Blue Jay Listening Room, and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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