Hotels near Mayo Clinic Florida

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Mayo Clinic Florida

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (427)
"Great facility to stay."
The price is P10,176
P11,550 total
includes taxes & fees
Oct 4 - Oct 5
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

3.0 star property
9.2 out of 10, Wonderful, (517)
"Employees were very nice and place was clean. Free breakfast was small but decent. It’s no Disney resort but it’s a great bang for your buck! Would stay again, 100%. "
The price is P6,629
P7,524 total
includes taxes & fees
Oct 9 - Oct 10
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1013)
"It was a great stay "
The price is P6,870
P7,798 total
includes taxes & fees
Oct 5 - Oct 6
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very Good, (741)
"Nice hotel, close to shops and mayo clinic."
The price is P11,455
P13,002 total
includes taxes & fees
Oct 11 - Oct 12
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very Good, (1014)
"The staff was wonderful and the hotel neat and clean. I already booked my next visit and staying at the Holiday Inn & Suites in November! Highly recommended!! "
The price is P6,861
P7,788 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Hilton Jacksonville At Mayo Clinic

4.5 star property
The price is P10,164
P11,536 total
includes taxes & fees
Oct 11 - Oct 12
Hilton Jacksonville At Mayo Clinic

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (501)
"Excellent breakfast"
The price is P7,385
P8,382 total
includes taxes & fees
Oct 19 - Oct 20
Element Jacksonville Beach

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (373)
"Great value for the money and location "
The price is P6,759
P7,671 total
includes taxes & fees
Sep 30 - Oct 1
Salt Air Inn & Suites

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1008)
"Staff was great location perfect"
The price is P7,385
P8,382 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.6 out of 10, Exceptional, (1014)
"Always enjoy staying here when we come down from Va"
The price is P7,443
P8,448 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (3269)
"Great stay!"
Margaritaville Jacksonville Beach

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 star property
8.8 out of 10, Excellent, (1024)
"Enjoyed my stay"
The price is P7,364
P8,359 total
includes taxes & fees
Oct 12 - Oct 13
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2484)
"Clean room, friendly staff, and the beach was gorgeous! "
The price is P9,774
P11,093 total
includes taxes & fees
Oct 19 - Oct 20
Hampton Inn Jacksonville Beach/Oceanfront

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (288)
"Our favorite spot "
The price is P8,664
P9,834 total
includes taxes & fees
Sep 30 - Oct 1
The Hotel Palms

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (805)
"Fabulous staff, one friendly greeting, the restaurants are good, the beach is lovely, breakfast outstanding"
The price is P23,498
P27,886 total
includes taxes & fees
Sep 30 - Oct 1
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (682)
"Fitness center was World Class"
The price is P26,114
P30,804 total
includes taxes & fees
Sep 30 - Oct 1
The Lodge and Club at Ponte Vedra Beach

Best Western Oceanfront

2.5 star property
9.0 out of 10, Wonderful, (1002)
"This place is our favorite place to go to when we want to go to the beach ,great breakfast convenient"
The price is P7,326
P8,315 total
includes taxes & fees
Sep 30 - Oct 1
Best Western Oceanfront

TownePlace Suites by Marriott® Jacksonville Mayport

3.0 star property
9.8 out of 10, Exceptional, (26)
"Love this place. Will stay again for sure!"
The price is P7,792
P8,844 total
includes taxes & fees
Oct 5 - Oct 6
TownePlace Suites by Marriott® Jacksonville Mayport

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (603)
"Great beachfront property convenient to Jax Beach Pier."
The price is P9,827
P11,154 total
includes taxes & fees
Oct 19 - Oct 20
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.0 out of 10, Wonderful, (1006)
"Great hotel"
The price is P10,350
P11,748 total
includes taxes & fees
Oct 19 - Oct 20
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 42 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Residence Inn By Marriott Jacksonville - Mayo Clinic Area and Hilton Jacksonville At Mayo Clinic.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 42 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Gonzales Park. Attractions like Rhoda Martin Cultural Heritage Center and Beaches Museum & History Park highlight the local culture.

Explore a world of travel with Expedia

Explore a world of travel with Expedia