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Hotels near Mayo Clinic Florida

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Our top choices for Mayo Clinic Florida hotels

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
A modern kitchen with a bar area, seating, and a view of the outdoors.
A multi-story hotel with a central entrance, surrounded by well-maintained lawns and palm trees.
An outdoor patio area with seating and a central fire feature, surrounded by buildings and palm trees.

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
1.1 km from Mayo Clinic Florida
United States
LISA
P8,695
P9,868 total
includes taxes & fees
Nov 13 - Nov 14
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.
A modern lobby with a curved sofa, round coffee tables, and a large pillar.
A modern restaurant with a bar area, wooden ceiling, and large windows.
A modern bar area with a central hanging light fixture, bar stools, and a well-stocked liquor display.

2. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
0.8 km from Mayo Clinic Florida
United States
Brandy
P10,055
P11,412 total
includes taxes & fees
Nov 22 - Nov 23
Hilton Jacksonville at Mayo Clinic near Beaches
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
A multi-story hotel with a modern design, featuring a covered outdoor area with seating and a fire pit.
A hotel room with a bed, a sofa, a nightstand, and a wall-mounted lamp.
An outdoor patio with a pool, wooden pergola, and seating area.

3. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
United States
Lana
P7,823
P8,879 total
includes taxes & fees
Nov 22 - Nov 23
TownePlace Suites by Marriott Jacksonville East
A lobby with a reception desk, seating area, and a staircase.
A modern hotel room with a large bed, a blue sofa, a small table, and a wall-mounted lamp.
Lobby sitting area
A modern kitchen with a refrigerator, coffee machine, and a bakery display.

4. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.6 km from Mayo Clinic Florida
United States
Gregory
P6,678
P7,579 total
includes taxes & fees
Nov 14 - Nov 15
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
A hotel lobby with a bar area, seating arrangements, and a reception desk.
An outdoor patio with a brick wall, a round table with striped chairs, and two large umbrellas.
A hotel room with a bed, a desk, a sofa, and a small table. There is a mirror, a lamp, and a picture on the wall.
A gym with treadmills, elliptical machines, a bench press, and a rack of dumbbells.

5. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
United States
Kerry
P7,548
P8,567 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
An outdoor seating area with stone fire pit, wicker furniture, and potted plants.
A modern living room with two armchairs, a sofa, a coffee table, and a flat-screen TV mounted on the wall.
A modern hotel lobby with a flat-screen TV, a fireplace, comfortable seating, and a coffee bar.
A hotel pool area with lounge chairs and umbrellas, surrounded by multi-story buildings with balconies.

6. Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
0.4 km from Mayo Clinic Florida
United States
Patricia
P9,667
P10,972 total
includes taxes & fees
Oct 31 - Nov 1
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
A bedroom with a bed, a pillow, a surfboard, and wall decorations.
A cafe with a front desk, a coffee machine, and two chairs outside.
A marble table with a book and a cup, a vase with green plants, and a brown sofa in the background.
A kitchen with a sink, a coffee maker, a bottle of Mountain Valley Spring Water, and a jar of cream cheese stuffed olives.

7. Hotel Palms

Hotel Palms
7.8 km from Mayo Clinic Florida
United States
Vinny
P12,442
P14,121 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Palms
A multi-story hotel with a modern design, featuring a covered entrance and a parking area with handicapped accessibility.
A hotel lobby with a reception desk, seating area, and a large window.
A beverage refrigerator stocked with various drinks, a small refrigerator, and a wall-mounted display with promotional items.
A coastal cityscape with a long beach, a large hotel with a curved facade, and a clear sky.

8. Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Southside, 7.7 km from Mayo Clinic Florida
United States
Aneudi
P6,106
P6,930 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.
A pathway leading to a sunset over a beach with sand and grass.
A modern hotel lobby with a long reception desk, seating area, and large windows.
A modern conference room with a long table, several chairs, and pendant lighting.

9. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
5.4 km from Mayo Clinic Florida
United States
ariel
P9,158
P10,395 total
includes taxes & fees
Nov 8 - Nov 9
Element by Marriott Jacksonville Beach
An outdoor patio area with seating, a fire pit, and a barbecue grill.
A modern hotel with a sign reading "Towneplace Suites by Marriott" and a parking lot in front.
A modern kitchen with wooden cabinets, a central island with jars, and a countertop with toasters.
A reception area with a modern design, featuring a reception desk, a refrigerator with snacks, and a wooden slatted wall.

10. TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
10.8 km from Mayo Clinic Florida
United States
irina
P7,568
P8,590 total
includes taxes & fees
Nov 15 - Nov 16
TownePlace Suites by Marriott® Jacksonville Mayport
Exterior
A modern kitchen with built-in appliances, wooden cabinetry, and a stainless steel refrigerator.
A conference room with multiple tables and chairs, large windows with curtains, and a flat-screen TV mounted on the wall.
Lobby

11. Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
Deerwood, 7.8 km from Mayo Clinic Florida
United States
Mandy
P7,695
P8,734 total
includes taxes & fees
Oct 31 - Nov 1
Hyatt Studios Jacksonville/St Johns Town Center
A modern hotel with a pool, palm trees, and a clear blue sky.
A modern bar area with seating, a bar counter, and a view of the city through large windows.
An outdoor seating area with white furniture and a well-maintained lawn, surrounded by large windows and a modern building facade.
A modern hotel building with a flat facade, large windows, and a sign reading "ACHTEL JACKSONVILLE".

12. AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
Southside, 8.1 km from Mayo Clinic Florida
United States
Emily
P9,476
P10,756 total
includes taxes & fees
Nov 22 - Nov 23
AC Hotel Jacksonville St Johns Town Center
A modern hotel room with two beds, a flat-screen TV, a desk, and a large window with a view of a building.
An outdoor seating area with a fire feature, chairs, and a table.
A modern bar area with a counter, bar stools, and a television screen.
A gym with treadmills, dumbbells, and exercise balls, overlooking a swimming pool.

13. Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
Southside, 10.8 km from Mayo Clinic Florida
United States
Cheryl A
P6,551
P7,435 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Indigo Jacksonville-Deerwood Park by IHG
A pool with a waterfall feature, surrounded by large rock formations.
An outdoor seating area with round tables and blue chairs, shaded by blue umbrellas with a logo, in front of a building with balconies and palm trees.
A bar with a tiled roof, outdoor seating, and a view of the ocean.
A beachfront hotel with multiple balconies, a sandy beach, and ocean views.

14. Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
6.3 km from Mayo Clinic Florida
United States
Maya
P10,217
P11,597 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Jacksonville Beach/Oceanfront
An outdoor patio with seating, a fire pit, and string lights.
A multi-story hotel with a modern design, featuring a large number of windows and a flat roof.
A modern living room with a dining area, a flat-screen TV, and a bookshelf.
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a fence.

15. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
Southside, 8.6 km from Mayo Clinic Florida
United States
Becky
P8,090
P9,182 total
includes taxes & fees
Oct 29 - Oct 30
Hyatt Place Jacksonville / St. Johns Town Center
A modern restaurant with high ceilings, large windows, and a mix of seating arrangements including booths and tables.
A modern bar area with wooden accents, a variety of beverages, and seating arrangements.
A modern hotel lobby with a sofa set, armchairs, a coffee table, and a patterned carpet.
A patio area with a stone fire pit, outdoor furniture, and a brick floor.

16. Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
Arlington, 13.2 km from Mayo Clinic Florida
United States
Chloie Marie
P5,676
P6,442 total
includes taxes & fees
Oct 31 - Nov 1
Courtyard by Marriott Jacksonville I-295/East Beltway
A modern hotel reception area with a curved wooden reception desk, a digital display, and a view of the lobby.
A modern lounge area with seating, tables, and hanging lights.
A snack display in a store with various chips and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.

17. Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
Southside, 8.7 km from Mayo Clinic Florida
United States
Janice
P6,963
P7,903 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Jacksonville St Johns Town Center
A hotel lobby with a reception desk, seating area, and a wall with a mountain design.
A hotel room with two beds, a desk with a computer, a chair, and a colorful carpet.
A pier extending into the ocean at sunset with birds flying above.
A buffet with multiple self-service stations, including omelets and other prepared foods.

18. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
4.6 km from Mayo Clinic Florida
United States
Bobby
P7,250
P8,229 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Jacksonville Beach by IHG
A spacious lobby with a reception desk, seating area, and large windows.
A bar area with wooden chairs, a round table, and a brick wall.
An indoor dining area with tables and chairs, a ceiling fan, and a view of the outdoors.
A multi-story hotel with a central entrance, large windows, and a well-lit facade.

19. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
8.5 km from Mayo Clinic Florida
United States
Madison
P7,249
P8,083 total
includes taxes & fees
Nov 16 - Nov 17
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
A terrace with wooden tables and chairs, overlooking a beach and a pier.
A beach with a wooden boardwalk leading to a pier.
A spacious outdoor dining area with wooden tables and chairs, a bar with stools, and large windows offering a view of the ocean.
A bar area with wooden beams, wicker hanging lights, and a bar stocked with bottles.

20. Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
5.8 km from Mayo Clinic Florida
United States
Ovidiu
P10,758
P12,210 total
includes taxes & fees
Nov 1 - Nov 2
Springhill Suites By Marriott Jacksonville Beach Oceanfront
View all properties

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
9.4
Exceptional
613 reviews
View
A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.
Hilton Jacksonville at Mayo Clinic near Beaches
9.2
Wonderful
386 reviews
View
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
TownePlace Suites by Marriott Jacksonville East
9.2
Wonderful
667 reviews
View
A lobby with a reception desk, seating area, and a staircase.
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
9.0
Wonderful
1,020 reviews
View
A hotel lobby with a bar area, seating arrangements, and a reception desk.
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
9.0
Wonderful
1,003 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

10/10 Excellent
"All was great from beginning to end."
Brian 3-night trip
Posted 15 hours ago
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Best Western Oceanfront

Best Western Oceanfront

8/10 Good
"Would stay again"
Williams 1-night trip
Posted 17 hours ago
Best Western Oceanfront
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

8/10 Good
"Staff was great, breakfast was very good as well"
Gino 2-night trip
Posted 17 hours ago
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

10/10 Excellent
"The room was very clean and comfortable. It would be nice to have the breakfast time last longer than 9:00am though."
Lana 2-night trip
Posted 2 days ago
TownePlace Suites by Marriott Jacksonville East

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 44 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville at Mayo Clinic near Beaches and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 44 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea, and Blue Jay Listening Room. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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