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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
Hotel in Jacksonville with free breakfast and a 24-hour fitness center

Choose dates to view prices

Located in the heart of Jacksonville, Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers warm hospitality with a free breakfast buffet. Guests can relax by the poolside bar, explore the garden, or use the coworking spaces and concierge services.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Bar
  • Housekeeping
  • Kitchen
  • Gym
The current price is P8,790
P9,977 total
includes taxes & fees
Nov 24 - Nov 25

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking, Corner

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Non Smoking, Corner

9.8 out of 10
Exceptional
(6 reviews)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Kitchen
Refrigerator
  • 50 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Non Smoking, Corner

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Non Smoking, Corner

10.0 out of 10
Exceptional
(3 reviews)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 60 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking

Fridge, microwave, stovetop, dishwasher

Studio Suite, 1 King Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(80 reviews)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Kitchen
Refrigerator
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Non Smoking

Living room

Studio Suite, 1 Bedroom, Non Smoking

9.8 out of 10
Exceptional
(17 reviews)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 52 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Tub)

8.0 out of 10
Very good
(4 reviews)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Hearing Accessible)

8.0 out of 10
Very good
(1 review)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Roll-In Shower)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed, Non Smoking (Mobility Accessible, Roll-In Shower)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.0 out of 10
Very good
(1 review)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 52 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking, Corner (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Non Smoking, Corner (Hearing Accessible)

8.0 out of 10
Very good
(1 review)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 50 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Non Smoking, Corner (Mobility/Hearing Access, Roll-In Shwr)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Non Smoking, Corner (Mobility/Hearing Access, Roll-In Shwr)

Highlights

Separate dining area
Separate sitting area
Air conditioning
Heating
Connecting rooms available
Kitchen
Refrigerator
Dishwasher
  • 60 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

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About the neighborhood

Map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224

What's nearby

  • Mayo Clinic Florida - 17 min walk - 1.5 km
  • University of North Florida - 5 min drive - 9.0 km
  • St. Johns Town Center - 7 min drive - 11.6 km
  • Mayport Naval Station - 16 min drive - 18.5 km
  • Jacksonville Naval Air Station - 29 min drive - 47.7 km

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 13 min drive

Restaurants

  • ‪Culver's #964 - ‬4 min drive
  • ‪M Brothers at Mayo - ‬18 min walk
  • ‪Starbucks - ‬4 min drive
  • ‪Circle K - ‬10 min walk
  • ‪Mayo Clinic - Employee Cafeteria - ‬18 min walk

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hotel near St. Johns Town Center
A free breakfast buffet, a poolside bar, and a free grocery shopping service are just a few of the amenities provided at Residence Inn By Marriott Jacksonville - Mayo Clinic Area. In addition to a garden and dry cleaning/laundry services, guests can connect to free in-room WiFi.
Additional perks include:
  • An outdoor pool along with sun loungers
  • Free self parking
  • Express check-out, smoke-free premises, and luggage storage
  • A water dispenser, a 24-hour front desk, and a computer station
  • Guest reviews speak highly of the helpful staff
Room features
All 155 rooms offer comforts such as laptop-compatible safes and laptop-friendly workspaces, in addition to perks like air conditioning and separate sitting areas. Guest reviews speak positively of the clean rooms at the property.
Extra conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Bathrooms with tubs or showers and free toiletries
  • 55-inch Smart TVs with Netflix, streaming services, and premium channels
  • Separate sitting areas, separate dining areas, and kitchens

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Hilton Jacksonville At Mayo Clinic
  • Pool
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  • Free WiFi
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9.4 out of 10, Exceptional, 23 reviews
The price is P7,024
P7,972 total
includes taxes & fees
Dec 20 - Dec 21
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Change of bedsheets (on request)
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Multilingual staff
  • Wedding services

Business services

  • 2 meeting rooms
  • 2,678 square feet of conference space
  • 24-hour business center
  • Computer station
  • Coworking space

Outdoors

  • Barbecue grill
  • Garden
  • Picnic area
  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical outlets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

More

  • 1 building
  • 7 floors
  • At least 80% lighting from LEDs
  • Ballroom
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2020
  • Communal living room
  • Comprehensive food waste policy
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • Smoking not allowed
  • Traditional architecture
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Stovetop
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Energy-saving switches in guestrooms
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 150 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 40 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Deposit: USD 125 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Pet fee: USD 150 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Frequently asked questions

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a pool?

Yes, this property has an outdoor pool.

How much does it cost to stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

As of Nov 19, 2025, prices found for a 1-night stay for 2 adults at Residence Inn By Marriott Jacksonville - Mayo Clinic Area on Nov 24, 2025 start from P 8,790.26, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Residence Inn By Marriott Jacksonville - Mayo Clinic Area pet-friendly?

Yes, this property allows cats and dogs (limit 2 total) with a maximum weight of up to 40 lbs per pet. There's a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much is parking?

Self parking is free at this property.

What time is check-in at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM. Late check-in is available during limited hours.

What time is check-out at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Check-out is at 11:00 AM.

Where is Residence Inn By Marriott Jacksonville - Mayo Clinic Area located?

Located in Isle of Palms, this hotel is 0.9 mi (1.5 km) from Mayo Clinic Florida and within 6 mi (10 km) of Windsor Commons Shopping Center and Windsor Parke Golf Club. Adventure Landing and South Beach Park and Sunshine Playground are also within 6 mi (10 km).

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Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 349 out of 440 reviews
Rating 8 - Good. 63 out of 440 reviews
Rating 6 - Okay. 12 out of 440 reviews
Rating 4 - Poor. 12 out of 440 reviews
Rating 2 - Terrible. 4 out of 440 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Gary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great facility to stay.
Stayed 1 night in Sep 2025

10/10 Excellent

james

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent place to Stay!!
Stayed 1 night in Jul 2025

10/10 Excellent

Jamie

Liked: Cleanliness, amenities, property conditions & facilities
Great
Stayed 1 night in Nov 2025

10/10 Excellent

Jacob

All was good
Stayed 1 night in Nov 2025

10/10 Excellent

Kimberly

Liked: Cleanliness, amenities, property conditions & facilities
Yes room was clean!! We appreciate being able to add an additional nights stay, as we encountered an emergency overnight Stay at the hospital. Mayo Clinic patient.
Stayed 3 nights in Oct 2025

10/10 Excellent

KENNETH

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property was clean, fairly new, comfortable, and the staff was friendly and helpful.
Stayed 2 nights in Jul 2025

10/10 Excellent

Carrie

Liked: Cleanliness, amenities, property conditions & facilities
The place was clean and staff was wonderful. Will be staying again!
Stayed 1 night in Jun 2025

10/10 Excellent

Gerald

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room and bedroom was very well done
Stayed 2 nights in Aug 2025

10/10 Excellent

Carolyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent accommodations!
Stayed 1 night in May 2025

10/10 Excellent

Tyeisha

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Terrific Stay 10/10

I had an amazing stay. The staff was friendly, the room was spotless. All the attractions were minutes away. The hotel felt like home away from home. Highly recommended. I will be back.
Stayed 2 nights in Aug 2025

10/10 Excellent

Amit

Liked: Cleanliness, amenities, property conditions & facilities
We drove from WV and stopped after a long drive. The room was comfortable and check-in / checkout was efficient. Breakfast was good as well.
Stayed 2 nights in Jul 2025

10/10 Excellent

Nadine

Liked: Cleanliness, amenities, property conditions & facilities
great stafff comfortable clean room and amenities
Stayed 2 nights in Jun 2025

8/10 Good

TASHA D.

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This property is closed to the Mayo Clinic
Stayed 1 night in Aug 2025

4/10 Poor

Daniel

Liked: Cleanliness
Once again upon arrival we were given a room in a lower category than the one we had booked. This is very disappointing and we will not be staying at this hotel again.
Stayed 1 night in Oct 2025

6/10 Okay

David

Liked: Cleanliness, property conditions & facilities
Marriot… a room refresh does not include making the bed? WTAF?! Also, no smoking means no smoking. A man smoked a cigar in the court yard without any interference from the staff. It’s too bad, the room was spacious and clean but the follow through in non existent.
Stayed 3 nights in Nov 2025

10/10 Excellent

Tibor

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Very clean and comfortable! Great breakfasts too!

Everything was wonderful!
Stayed 6 nights in Apr 2025

10/10 Excellent

Helmuth

Liked: Cleanliness, staff & service, property conditions & facilities
We stayed there for 6 days. Our room was quiet, very clean, nice view to the woods. It was nice that they had a free shuttle to Mayo Clinic. The only problem was that one day we did’t had our room clean because the person in charge of doing it forgot. I have to go back to Mayo Clinic and my stay at the hotel was so good that I already made my reservation for the Residence Inn
Stayed 7 nights in Sep 2025

10/10 Excellent

SHERICE

Liked: Cleanliness, amenities, property conditions & facilities
Very nice. About 3.5 miles from the beach. Breakfast was amazing especially loved their coffee.
Stayed 2 nights in Jul 2025

10/10 Excellent

Sara

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place highly recommend
Stayed 2 nights in Mar 2025

8/10 Good

Anishma

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved my stay!
Stayed 1 night in Dec 2024

8/10 Good

Gerard

Liked: Cleanliness, staff & service, property conditions & facilities
Was perfect place to stay on my visit to Mayo.
Stayed 2 nights in Dec 2024

10/10 Excellent

Stephen

Liked: Room comfort

Excellence in Hospitality

Mayo Clinic appointment; staff was professional in assisting with appointments vs hotel needs.
Stayed 1 night in Jul 2025

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay!

This is a wonderful place to stay. It offers all of the services that you need. It is in a beautiful setting with great amenities.
Stayed 2 nights in Apr 2025

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Definitely will be staying here anytime we are in

stayed here for a mayo clinic appointment everything was amazing from the time of check-in to check-out.
Stayed 3 nights in Feb 2025

10/10 Excellent

brenda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Super happy!!! 2nd time staying here ! Satisfied 2nd time around ! Will be our stay every year we visit Jacksonville!
Stayed 2 nights in Jun 2025