Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A historic church with a dome and bell tower, surrounded by trees and a fountain in a public square.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

P2,001
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

P1,382
per adult
94% of travellers recommend
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
Michaelangelo's David

Accademia timed-entry Ticket with App Guide

P2,834
per adult
90% of travellers recommend
Accademia timed-entry Ticket with App Guide
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

P9,421
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery

P5,797
per adult
98% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
Florence: Street Food Walking Tour with Wine

Florence: Street Food Walking Tour with Wine

P3,913
per adult
100% of travellers recommend
Florence: Street Food Walking Tour with Wine
See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundable
The price is P9,192 per night from Nov 3 to Nov 4
P9,192
P11,098 total
Nov 3 - Nov 4
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is P7,732 per night from Nov 8 to Nov 9
P7,732
P9,492 total
Nov 8 - Nov 9
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...
9/10 Wonderful! (342 reviews)
"The location of the hotel was amazing and central with everything within walking distance. The checkin was smooth and the receptionist was warm. In terms of value for money, we thought the price was higher for the quality of the rooms. The hotel has a nice homely feel though I believe the showers ..."

Reviewed on Oct 8, 2026

La Torre Del Cestello
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
The price is P4,435 per night from Nov 8 to Nov 9
P4,435
P5,443 total
Nov 8 - Nov 9
includes taxes & fees
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...
8/10 Very Good! (65 reviews)
"No"

Reviewed on Jul 30, 2026

Hostel Santa Monaca
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is P7,445 per night from Nov 2 to Nov 3
P7,445
P9,177 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and premium bedding. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,188 reviews)
"Great place. Easy to navigate to and from. Quiet, yet close to everything."

Reviewed on Oct 7, 2026

Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is P6,174 per night from Nov 8 to Nov 9
P6,174
P7,779 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,002 reviews)
"The entrance, the building, the lobby looked very well and promising. Room was small but ok. The shower was terrible, poor mainteined. Room decoration looked agressive. Breakfast was great. Location little far from downtown"

Reviewed on Sep 6, 2026

UNA Hotels Vittoria Firenze
Hotel Firenze 2000

Hotel Firenze 2000

2 out of 5
Viale Raffaello Sanzio, 16 Florence FI
The price is P11,798 per night from Oct 23 to Oct 24
P11,798
P13,612 total
Oct 23 - Oct 24
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Ponte Vecchio and Piazza del Duomo are located ...
7.2/10 Good! (208 reviews)
"Me gusto la ubicación, estamos lo suficientemente cerca de Florencia sin estar en el centro, pero tampoco tan lejos. La habitación no era como en las fotos, a pesar de que la habitación se encontraba muy limpia, los edredones y las sabanas eran viejas, al igual que el TV, aunque todo cumplió su función. ..."

Reviewed on Oct 8, 2026

Hotel Firenze 2000
See all 538 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito

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