Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art scene and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Piazza del Carmine
You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its fascinating museums.
Things to do
Small-Group Wine Tasting Experience in the Tuscan Countryside
Florence Accademia Gallery Tour with Entrance Ticket Included
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
Florence Day Trip: Medieval Villages & Cooking Class
SMALL-GROUP Wine Safari: Tuscany Wine Tasting Tour from Florence
Top hotels in Santo Spirito
Hotel Horto Convento
Everyone very helpful
Reviewed on Apr 7, 2026
Palazzo Mannaioni Suites
I had a great stay at this hotel. Everything was excellent—from the convenient location to the cleanliness and the spacious room size. It made my trip very comfortable, and I would definitely stay here again. Just need some work in Wi Fi
Reviewed on Apr 3, 2026
La Torre Del Cestello
Very nice place in the centre of town. Extremely helpful and friendly staff. Room was exactly as advertised , spacious with a great view overlooking the river and old town. If i go back to Florence i would happily stay here again.
Reviewed on Apr 7, 2026
Foresteria Valdese di Firenze - Casa per Ferie
The staff was amazing.
Reviewed on Apr 10, 2026
UNA Hotels Vittoria Firenze
Helpful staff. Vey good breakfast. Clean and comfortable room.
Reviewed on Apr 1, 2026
Palazzo Oliveto
The room was not that clean, there was mold on the shower, there were some stains on the wall. The higienic part of the overall room is the reason why I give 2.
Reviewed on Nov 10, 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.
Oltrarno
Oltrarno is a destination visitors seek out for is fascinating museums, picturesque gardens, and beautiful river views. You might also want to check out attractions like Pitti Palace or Santo Spirito Basilica while you're exploring the neighborhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
Historic Centre of Florence
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral, and stunning river views.
Duomo
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
