A grand church interior with high vaulted ceilings, large columns, and a central altar.

Santo Spirito Hotels near Florence

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (713 reviews)
"We had a wonderful stay - the property was beautiful, breakfast was great, and the staff were SO helpful and accommodating. I would recommend this hotel to anyone."
Canada
CHRISTINE
The price is P11,172
P13,298 total
includes taxes & fees
Aug 31 - Sep 1
Hotel Horto Convento

2. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very Good, (1,006 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
United Kingdom
Glenn
The price is P5,307
P6,847 total
includes taxes & fees
Aug 30 - Aug 31
UNA Hotels Vittoria Firenze

3. Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,159 reviews)
"We loved it!"
United States
Beatriz
The price is P7,609
P9,379 total
includes taxes & fees
Aug 24 - Aug 25
Palazzo Mannaioni Suites

4. La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (296 reviews)
"Lovely residence-style building in a quieter neighborhood that is close to all you need."
Canada
Jayme
The price is P6,196
P7,824 total
includes taxes & fees
Aug 31 - Sep 1
La Torre Del Cestello

5. Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (201 reviews)
"This was a quaint little hotel. It was has a really friendly vibe. It’s a bit dated, but it only adds to its charm. I would return to this hotel. "
United States
Martin
The price is P4,832
P5,963 total
includes taxes & fees
Aug 26 - Aug 27
Hotel Firenze 2000

6. AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (238 reviews)
"A delight - the perfect escape from the hustle and bustle of Florence A great room full of character The terrace was perfect for breakfast and an early evening drink The staff were very helpful with great restaurant recommendations"
United Kingdom
Peter
The price is P20,638
P23,711 total
includes taxes & fees
Aug 25 - Aug 26
AdAstra Suites

7. 1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (203 reviews)
"We had an amazing stay at 1900 Artevita. Friendly staff and very convenient location with close bus stop and comfortable walk to city centre"
Canada
Miket
The price is P4,069
P5,340 total
includes taxes & fees
Aug 23 - Aug 24
1900 Artevita

8. Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (176 reviews)
"Quaint boutique hotel in great location. Clean comfortable room and nice breakfast. Wonderful restaurant almost next door and close to train station. Highly recommend."
United States
Timothy
The price is P14,054
P16,468 total
includes taxes & fees
Sep 6 - Sep 7
Ottantotto Firenze

9. Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (380 reviews)
"Excellent location and wonderful staff in a unique building with an amazing history."
United Kingdom
Matthew
The price is P7,716
P9,353 total
includes taxes & fees
Aug 23 - Aug 24
Casa Santo Nome di Gesù

10. Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (136 reviews)
"Amazing location, charming hotel and great breakfast"
Sweden
Carin
The price is P15,626
P18,198 total
includes taxes & fees
Aug 23 - Aug 24
Oltrarno Splendid

11. Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (212 reviews)
"Historic vibes, clean room, nice view, helpful staff. Breakfast was included and all you can eat. Food was fresh and coffee was good."
United States
Samuel
The price is P18,274
P20,966 total
includes taxes & fees
Aug 25 - Aug 26
Hotel Palazzo Guadagni

12. La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is P6,376
P7,879 total
includes taxes & fees
Aug 25 - Aug 26
La Fonderia Firenze

13. Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is P39,166
P44,092 total
includes taxes & fees
Sep 21 - Sep 22
Torre di Bellosguardo

14. Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (152 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is P9,896
P11,751 total
includes taxes & fees
Aug 31 - Sep 1
Drom Florence Rooms & Apartments

15. Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (106 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Belgium
Mary Mariam
The price is P4,566
P5,887 total
includes taxes & fees
Aug 24 - Aug 25
Palazzo Oliveto

16. Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (235 reviews)
"I had a lovely stay! Staff were helpful"
United States
Alloura
The price is P5,116
P6,493 total
includes taxes & fees
Aug 31 - Sep 1
Foresteria Valdese di Firenze - Casa per Ferie

17. Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (44 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
United States
Juliet
The price is P4,416
P11,488 total
includes taxes & fees
Aug 23 - Aug 24
Appartamenti degli Artisti by Mmega

18. Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (77 reviews)
"Wonderful stay again here-our second time. Beautifully clean, perfect location and friendly staff-thankyou for another lovely stay!"
United Kingdom
Victoria
The price is P5,602
P7,027 total
includes taxes & fees
Aug 23 - Aug 24
Home in Florence

19. B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very Good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
United Kingdom
Wayne
The price is P5,238
P6,627 total
includes taxes & fees
Aug 25 - Aug 26
B&B Mia Palace

20. Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (168 reviews)
"Excellent place"
United States
Laura Patricia
The price is P7,191
P8,919 total
includes taxes & fees
Aug 26 - Aug 27
Residenza D'Epoca Al Numero 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Piazza Santo Spirito: Experience the lively atmosphere of the piazza, filled with friendly locals and charming cafés.
  • Cultural Richness: Explore the historic San Spirito church and regal palace, immersing yourself in the Florentine Renaissance.
  • Wine Tours: Delight in Tuscany's renowned wines through guided tours that showcase the region's exquisite flavours.
  • Trendy Neighbourhood: Enjoy luxury dining and outdoor experiences in a trendy area, perfect for relaxation and exploration.
  • Diverse Accommodation: Choose from a variety of lodgings, including charming bed & breakfasts and unique stays with antique furnishings.

Find great hotels near Santo Spirito

In the charming district of Santo Spirito, Florence, you'll discover a delightful selection of accommodation options, including hotels and bed & breakfasts. This area caters to a variety of travellers, offering city-themed lodgings, pet-friendly stays, and unique experiences featuring antique furniture. Whether you prefer a loft in Florence or a stay near the historic Palazzo Ridolfi, Santo Spirito provides an inviting atmosphere to explore the rich heritage of Tuscany.

  • The Social Hub Florence Lavagnini: A vibrant 4-star hotel, The Social Hub Florence Lavagnini offers a distinctive blend of adventure and urban sophistication. Located 2km from Santo Spirito, this property caters to the adventurous traveller and business-minded individuals alike. Guests can enjoy a variety of onsite and nearby recreation activities, making it an excellent choice for those looking to explore the dynamic city of Florence. The hotel features modern amenities and a lively atmosphere that encourages social interaction, ensuring a memorable city-themed vacation experience.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Situated 1km from Santo Spirito, this 4-star hotel is ideal for families seeking adventure and quality time together. B&B Hotel Firenze Pitti Palace al Ponte Vecchio provides a warm and welcoming environment, with amenities tailored for children, such as onsite childcare services. Guests can also indulge in nearby adventure sports, including bicycle rentals, allowing for a unique way to explore Florence's charming streets. The hotel’s family-friendly atmosphere and convenient location make it perfect for unforgettable family vacations.
  • Grand Hotel Cavour: With a guest rating of 9.2 out of 10, the Grand Hotel Cavour is a refined 4-star establishment located 2km from Santo Spirito. This hotel is well-suited for families and business travellers, offering childcare services and amenities for children, ensuring a comfortable stay for guests of all ages. Its elegant design and central location make it an ideal base for exploring Florence's rich culture and history. The hotel’s combination of business facilities and family-oriented services create a balanced environment for both leisure and work-related trips.

Where to stay near Santo Spirito

Santo Spirito is a charming neighbourhood in Florence, where culture and history intertwine beautifully. Visitors can explore the lively Piazza Santo Spirito, basking in the vibrant atmosphere created by friendly locals. This area offers a glimpse into the Florentine Renaissance, with its romantic streets and secluded corners. Embrace the trendy vibe while enjoying luxury dining and outdoor experiences, making it a perfect base for your Tuscan adventure.

  • Florence: As the birthplace of the Renaissance, Florence is a vibrant city that offers a rich cultural experience. Located in the heart of Tuscany, it attracts visitors throughout the year, with peak seasons in March to April and September. Florence is known for its bustling shopping areas, relaxing spas, and theatre performances. Key landmarks include the iconic piazza squares and historic sites that define the city's artistic heritage. Exploring Florence allows you to immerse yourself in a city where art, culture, and history converge.
  • Historic Centre of Florence: Just 1.6km away from Santo Spirito, the Historic Centre of Florence is a UNESCO World Heritage site that showcases the splendour of medieval and Renaissance architecture. This neighbourhood experiences moderate seasonal fluctuations in visitor numbers, peaking from July to September. Attractions such as public markets and theatres provide a lively atmosphere, while notable landmarks like the famed historic bridges and picturesque piazza squares make it a must-visit. The area is perfect for those seeking a blend of culture and family-friendly experiences.
  • Duomo: Located a mere 1km from Santo Spirito, Duomo is renowned for its breathtaking cathedral and stunning dome, which dominate the skyline. This neighbourhood sees a similar seasonal pattern to the Historic Centre, with peak visitor numbers in the summer months. Duomo offers vibrant markets and shopping areas, catering to those looking for local goods and unique souvenirs. The proximity to historic places and tourist precincts enhances its appeal, making it an essential stop for anyone wishing to explore Florence’s rich history and lively culture.

Things to do near Santo Spirito

Shopping

Santo Spirito offers a charming shopping experience with local boutiques and artisan shops. Visit the lively Mercato di Santo Spirito for unique souvenirs and handmade crafts. The area is known for its vibrant atmosphere and traditional Florentine products, making it an excellent spot for memorable gifts.

Recreation

In Santo Spirito, immerse yourself in the serene atmosphere of a local wellness centre, where you can enjoy rejuvenating massages and holistic therapies. Explore the nearby Oltrarno district, offering tranquil parks for leisurely strolls and art workshops that promote relaxation and creativity.

Adventure

Experience the thrill of motor racing at Mugello Circuit, located 27km from Santo Spirito. Feel the adrenaline rush as you watch high-speed races and enjoy the vibrant sports atmosphere, making it a memorable adventure for motorsport enthusiasts.

Nightlife

Explore the vibrant nightlife at Caffè degli Artigiani, where you can enjoy artisanal cocktails in a lively atmosphere. For a memorable experience, visit La Ménagerie for its eclectic vibe and local DJs spinning tunes late into the night.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santo Spirito

To save on your visit to Santo Spirito, consider travelling during the off-peak months of January to February or November when prices are lower. Booking your hotel about a month in advance can secure better rates, with Mondays being the most affordable nights to stay. Use Expedia to find last-minute deals and filter options based on your budget and preferences. Walking is an excellent way to explore the area, keeping transport costs down, while combining hotel and flight bookings can provide additional savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santo Spirito are January to February and November, where the prices are slightly lower. This is in comparison to May to June and September, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Santo Spirito about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santo Spirito is Monday. The most expensive day to stay around Santo Spirito is Friday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional preferences. You can organise your results to display prices from lowest to highest, allowing you to view the most affordable hotels first. Furthermore, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santo Spirito with your flights and activities through an Expedia package.

Find the best attractions near Santo Spirito

Santo Spirito in Florence, Tuscany, is perfect for culture enthusiasts and city explorers alike. Visitors can enjoy the charming piazza, the historic church, and the regal palace, offering a rich cultural experience for families and travellers. Key attractions include the stunning San Spirito and the vibrant Santo Spirito Square, making it an ideal destination for those seeking to immerse themselves in local culture and history.

  • Cathedral of Santa Maria del Fiore: Marvel at the stunning architecture of this iconic cathedral, often referred to as the Duomo. Its remarkable dome, designed by Brunelleschi, dominates Florence's skyline and offers breathtaking views from the top. The intricate façade and beautiful interiors are steeped in rich cultural history, making it a must-see for visitors.
  • Ponte Vecchio: Stroll across Florence's oldest bridge, renowned for its charming shops selling jewellery and art. The bridge’s medieval architecture, complete with arched walkways, provides a picturesque setting, especially at sunset, creating a romantic atmosphere steeped in history.
  • Uffizi Gallery: Home to one of the most important collections of Renaissance art, the Uffizi offers an unparalleled journey through masterpieces by artists like Botticelli and Michelangelo. The gallery itself is a work of art, with stunning architecture and captivating views of the Arno River.

Best time to go to Santo Spirito

The best time to visit Santo Spirito is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are moderately high and weather is sunny. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Flying into Santo Spirito, Florence, is convenient with major airports nearby. Florence Airport (FLR-Peretola) is approximately 5km away, with luxurious hotels like Bernini Palace, Palazzo Montebello, and Hotel Lungarno, all offering various transport services to the airport. Bologna Airport (BLQ-Guglielmo Marconi) is 85km away, with options such as Grand Hotel Majestic and Starhotels Excelsior providing shuttle services. Pisa Airport (PSA-Galileo Galilei), located 68km from Santo Spirito, features excellent hotels like Bagni di Pisa Palace & Thermal Spa and Hotel Pisa Tower Plaza, both offering nearby access. Each airport ensures easy access to the chaRMIng city of Florence.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 524 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Piazza del Duomo are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

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