Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Piazza del Carmine
You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art scene.
Santo Spirito Basilica
Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Things to do
Florence Accademia Gallery Tour with Entrance Ticket Included
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Uffizi & Accademia Timed Entry: Small Group Duomo Walking Tour
Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia
City Sightseeing Florence Hop-on Hop-off Bus Tour
Top hotels in Santo Spirito
Hotel Horto Convento
Lovely location, staff were great
Reviewed on Feb 13, 2026
Palazzo Mannaioni Suites
The staff was amazing and we had a Great stay would recommend. Thank you!
Reviewed on Feb 23, 2026
UNA Hotels Vittoria Firenze
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!
Reviewed on Jan 1, 2026
La Torre Del Cestello
Staff and room were wonderful
Reviewed on Feb 23, 2026
Foresteria Valdese di Firenze - Casa per Ferie
Room was very dated, old and cold. Shower seemed particularly dirty and the water was cold. Of the 9 hotels we have stayed in on our travels thus far this was the only 3 star that on this site rated 4.4. Good location. Lovely staff. Wouldn’t stay again.
Reviewed on Jan 2, 2026
Casa Santo Nome di Gesù
Pretty neat place. Run by nuns. Great building. Friendly staff Breakfast included. Rooms simple clean. Beautiful location. Would definitely go back.
Reviewed on Jan 28, 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens.
Oltrarno
Oltrarno is a destination visitors seek out for is fascinating museums, picturesque gardens, and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighborhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
