Photo by PhotoJoy
Hotels with Spa in Panama
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Panama Hotels with Spa
Our top choices for Panama hotels with a spa

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1003)
The price is P9,343
P10,277 total
includes taxes & fees
Dec 21 - Dec 22

8.4 out of 10, Very Good, (2328)
The price is P6,477
P8,100 total
includes taxes & fees
Dec 18 - Dec 19

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz
9.6 out of 10, Exceptional, (638)
The price is P13,177
P14,495 total
includes taxes & fees
Jan 17 - Jan 18, 2026

9.0 out of 10, Wonderful, (1004)
The price is P8,330
P9,163 total
includes taxes & fees
Dec 21 - Dec 22

9.4 out of 10, Exceptional, (1005)
The price is P11,788
P12,966 total
includes taxes & fees
Jan 14 - Jan 15, 2026

8.2 out of 10, Very Good, (823)
The price is P5,310
P5,841 total
includes taxes & fees
Dec 20 - Dec 21

9.8 out of 10, Exceptional, (557)
The price is P22,741
P25,015 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews

Decapolis Hotel Panama City
10/10 Excellent
Explore a world of travel with Expedia
Hotel Theme
- Hotels with WiFi in Panama
- Hotels with Internet in Panama
- Hotels with free Internet in Panama
- Hotels with free wifi in Panama
- Hotels with Restaurants in Panama
- Hotels with Air Conditioning in Panama
- Hotels with parking in Panama
- Hotels with Breakfast in Panama
- Hotels with free parking in Panama
- Family friendly Hotels in Panama
- Hotels with free breakfast in Panama
- Hotels with Bars / Lounges in Panama
- Beach Hotels in Panama
- Hotels with Swimming Pool in Panama
- Hotels with shuttle in Panama
- Hotels with Airport Shuttle in Panama
- Business Hotels in Panama
- Hotels near Shopping Areas in Panama
- Hotels with Views in Panama
- Hotels with Balcony in Panama
More Themes
- Hotels with Air Conditioning
- Hotels with Airport Shuttle
- All Inclusive Resorts
- Hotels with Balcony
- Hotels with Bars / Lounges
- Beach Hotels
- Boutique Hotels
- Hotels with Breakfast
- Budget Hotels
- Business Hotels
- Casino Hotels
- Hotels with Childcare
- Hotels with connecting rooms
- Hotels with Restaurants
- Hotels with Entertainment
- Family friendly Hotels
- Hotels with Gyms
- Hotels with free airport shuttle
- Hotels with free breakfast
- Hotels with free parking
- Hotels with free wifi
- Golf Hotels
- Hotels with Hot Tubs
- Hotels with indoor pool
- Apartments
- Gay friendly Hotels
- Luxury Hotels
- Hotels with parking
- Pet friendly Hotels
- Hotels with Swimming Pool
- Romantic Hotels
- Hotels near Shopping Areas
- Hotels with smoking rooms
- Hotels with shuttle
- Hotels with Views
- Hotels with Waterparks
- Hotels with Waterslides
- Hotels with WiFi
- Hotels with Yoga
Discover hotels close to Panama with room rates, reviews, and availability. Most hotels are fully refundable.
Expedia's Latest Trends
Hotels
- Crystal Inn Hotel & Suites Salt Lake City
- Ximen Hotel
- Resorts Lapu-Lapu
- Millennium Hilton New York One UN Plaza
- Hotels in Naga City
- Obaid's Condo in Winland Towers
- Hotels in Malasiqui
- Hotels in Philippines
- Boutique Camping Bunja
- Hotels with Hot Tubs in Pasay
- The Altair Hotel Bay Harbor
- Sea Sand Sun Resort and Villas
- Hotels near Sands Expo and Convention Centre
- Luxur Place
- Hotels near Ayala Malls Serin
- Hotels in Hanoi
- Hotel Indigo Savannah Historic District by IHG
Flights










































