A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

Mediterranean Region 5 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mediterranean Region 5 Star Hotels

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Mediterranean Region 5-star hotels

A modern restaurant with high ceilings, large windows, and a view of the city.
A spacious living area with a large sectional sofa, a coffee table, and a dining area in the background.
A modern indoor pool area with a glass barrier, marble flooring, and a seating area with wooden panels and cushions.
A modern restaurant with a bar area, large windows, and hanging plants.

1. Grand Hyatt Athens

Grand Hyatt Athens
Neos Kosmos
Canada
Kristen
P9,718
P12,141 total
includes taxes & fees
Sep 10 - Sep 11
Grand Hyatt Athens
An outdoor dining area with tables and chairs, a large plant, and a view of a mountainous landscape.
A modern restaurant with round tables, ambient lighting, and a decorative wall with a fire feature.
A modern interior with a staircase, seating area, and potted plants.
A bar area with a circular chandelier, bar stools, and a variety of bottles and glasses.

2. Grand Hyatt Barcelona

Grand Hyatt Barcelona
Les Corts
United States
YESNEIDY
P14,351
P17,689 total
includes taxes & fees
Aug 30 - Aug 31
Grand Hyatt Barcelona
A modern restaurant with a central round table, surrounded by chairs, and a variety of plants and greenery.
A bar area with a wooden ceiling, hanging lights, and a variety of bottles on shelves.
An outdoor patio with wooden furniture, potted plants, and a pergola structure.
A spacious living area with a large window offering a city view, a round wall clock, and a seating arrangement with a coffee table.

3. Corinthia Lisbon

Corinthia Lisbon
Lisbon City Center
Canada
Christopher
P14,707
P16,164 total
includes taxes & fees
Aug 30 - Aug 31
Corinthia Lisbon
A modern building with a glass facade, outdoor seating area, and a staircase leading to the entrance.
A lobby with a modern reception desk, a large chandelier, and marble walls.
A restaurant with a bar area, booths, and a view of the outdoors.

4. Sofitel Athens Airport

Sofitel Athens Airport
Spata-Artemida
United States
Fabio
P27,012
P31,753 total
includes taxes & fees
Sep 1 - Sep 2
Sofitel Athens Airport
A bathtub with a city view, wooden walls, and a slatted ceiling.
A rooftop bar with outdoor seating and a pool, overlooking a cityscape at night.
A modern interior with a curved staircase, seating area, and large windows offering a city view.
A rooftop terrace with wooden flooring, cushioned seating, and tables.

5. Nobu Hotel Barcelona

Nobu Hotel Barcelona
Sants-Montjuïc
United Kingdom
ROSHNI
P16,915
P20,503 total
includes taxes & fees
Aug 30 - Aug 31
Nobu Hotel Barcelona
A rooftop pool with lounge chairs and umbrellas, offering a city view.
An outdoor dining area with tables set for a meal, overlooking a cityscape with historical buildings.
A modern hotel entrance with a geometric patterned facade, a glass revolving door, and a visible outdoor area with a metal railing.
A modern restaurant interior with large windows, contemporary furniture, and a decorative wooden partition.

6. InterContinental Barcelona by IHG

InterContinental Barcelona by IHG
El Poble-sec
United States
LIZBET
P17,300
P20,933 total
includes taxes & fees
Sep 2 - Sep 3
InterContinental Barcelona by IHG
An outdoor dining area with tables and chairs, overlooking a historic building.
A table with a champagne bottle, glasses, and a fruit platter, overlooking ancient ruins.
A rooftop terrace with a hot tub, lounge chairs, and a pergola.
A spacious lobby with a high ceiling, large columns, and a skylight.

7. Divani Palace Acropolis

Divani Palace Acropolis
Athens City Centre
Canada
Amanda
P11,967
P14,705 total
includes taxes & fees
Aug 31 - Sep 1
Divani Palace Acropolis
An indoor gym with cardio machines, a large exercise ball, and a view of palm trees and buildings through large windows.
A cozy indoor seating area with wooden furniture, cushioned benches, and large potted plants.
A restaurant with wooden tables and chairs, striped cushions, and a brick wall.

8. W Barcelona

W Barcelona
Barceloneta
United States
Karen
P23,815
P28,093 total
includes taxes & fees
Sep 20 - Sep 21
W Barcelona
A room with a large skylight, a view of a cityscape, and a cozy seating area with chairs.
A geodesic dome interior with seating and a view of a cityscape through large windows.
A modern building with a glass facade, a pool area with sun loungers and umbrellas, and a view of the pool.
A modern living room with a sectional sofa, armchairs, and a coffee table.

9. Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower
Bellvitge
United States
Cilas
P10,223
P11,958 total
includes taxes & fees
Sep 13 - Sep 14
Hyatt Regency Barcelona Tower
A water park with multiple slides and pools, surrounded by trees and a view of the sea.
A resort with a swimming pool, outdoor seating areas, and a prominent tower.
A hotel room with two beds, a desk, a TV, and a window with curtains.
A hotel room with a large bed, a desk, a chair, and a balcony with a view of greenery.

10. Swandor Hotels & Resort Topkapi Palace - All Inclusive

Swandor Hotels & Resort Topkapi Palace - All Inclusive
Lara
United States
Asli
P16,810
P18,659 total
includes taxes & fees
Sep 6 - Sep 7
Swandor Hotels & Resort Topkapi Palace - All Inclusive
A historic hotel with a classic architectural style, featuring a prominent corner entrance, multiple balconies, and a well-lit facade.
A balcony with wicker chairs, a glass table, and a potted plant with flowers.
A pool area with lounge chairs and a mural.
A buffet area with various food items, a decorative centerpiece, and a chandelier.

11. Wellington Hotel & Spa Madrid

Wellington Hotel & Spa Madrid
Salamanca
Canada
Niloufar
P24,901
P27,391 total
includes taxes & fees
Aug 31 - Sep 1
Wellington Hotel & Spa Madrid
A rooftop bar with a pool table, bar area, and seating, overlooking a cityscape at dusk.
A dining table set for two with a city view, two chairs, and various glassware.
A bar area with a large tree, multiple bar stools, and a view of the cityscape through large windows.
A modern building entrance with a prominent sign reading 'TIVOLI.'

12. Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
Lisbon City Center
United States
Heather
P21,281
P23,133 total
includes taxes & fees
Aug 31 - Sep 1
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
A Gothic cathedral with multiple spires, surrounded by urban buildings and a clear sky.
A room with a view of a historic building through a large window.
A room with a large window overlooking a historic building with intricate architecture.
A restaurant with large windows, wooden chairs, and tables.

13. Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
Downtown Barcelona
Canada
Joel
P21,172
P25,186 total
includes taxes & fees
Aug 31 - Sep 1
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
An indoor swimming pool with clear glass walls, potted plants, and a view of the cityscape.
A hotel room with a large bed, green pillows, a green throw blanket, a view of a cityscape through large windows, and a decorative mirror with geometric patterns.
The entrance of Barceló Torre de Madrid with glass doors, potted plants, and a sign for SOMOS restaurant and GAMA bar.
A window with a view of a cityscape, a potted plant with flowers, an open book, a teapot, and a cup on a windowsill.

14. Barceló Torre de Madrid

Barceló Torre de Madrid
Madrid Centro
United States
Stephen
P14,048
P15,453 total
includes taxes & fees
Aug 31 - Sep 1
Barceló Torre de Madrid
A resort pool with lounge chairs and umbrellas, surrounded by palm trees and a view of the sunset over the water.
A balcony with a sofa and a wooden table, overlooking a body of water and mountains.
A spacious living area with a round table, comfortable seating, a large chandelier, and a view of the sea.
A modern indoor pool area with a view of the sea, a seating area, and a plant arrangement.

15. Akra Antalya

Akra Antalya
Lara
United Kingdom
Karen
P15,529
P17,237 total
includes taxes & fees
Sep 27 - Sep 28
Akra Antalya
A spacious lobby with modern chandeliers, a glass staircase, and a seating area.
A person descending a modern staircase with glass railings and a large potted plant in the background.
A swimming pool with two people in the water, overlooking a cityscape and a body of water.
A multi-story hotel with a prominent sign reading "EPIC SANA".

16. EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
Lisbon City Center
United States
mehdi
P13,877
P15,284 total
includes taxes & fees
Aug 30 - Aug 31
EPIC SANA Lisboa Hotel
A modern hotel with a prominent "EPIC SANA" sign, featuring a grid-like facade and multiple floors.
An indoor dining area with tables set for meals, surrounded by potted plants and a ceiling covered in greenery.
A rooftop pool area with two lounge chairs, a table with a drink, and a large umbrella.
A modern indoor pool area with a large ceiling projection, a hot tub, and a fireplace.

17. EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
Lisbon City Center
United Kingdom
Neil Affan
P14,776
P16,238 total
includes taxes & fees
Aug 30 - Aug 31
EPIC SANA Marques Hotel
A large, ornate building with multiple balconies and a central dome, surrounded by palm trees.
A courtyard with multiple levels of balconies, arched windows, and outdoor seating areas.
A spacious lobby with a checkered floor, large windows, and a central seating area with sofas and armchairs.
A spacious courtyard with a central fountain, surrounded by tables and chairs, and ornate arches.

18. Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Historical Center
Mexico
Richard
P29,814
P32,796 total
includes taxes & fees
Aug 29 - Aug 30
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
A rooftop pool with lounge chairs and umbrellas, surrounded by buildings.
A room with a view of a cityscape, a potted plant, a book, and a cocktail on a tray.
A modern hotel room with a large bed, a leather armchair, a small table, and a view of the city.

19. Thompson Madrid, by Hyatt

Thompson Madrid, by Hyatt
Madrid Centro
Canada
Elena
P20,969
P23,066 total
includes taxes & fees
Aug 31 - Sep 1
Thompson Madrid, by Hyatt
A modern pool area with a unique architectural structure, palm trees, and a clear view of the ocean.
A modern hotel room with a large bed, a bathtub, and a view of the beach.
A modern hotel room with a large bed, a round table, and a view of the sea.
A hotel with a pool, a beach, and a Ferris wheel.

20. Hotel Arts Barcelona

Hotel Arts Barcelona
Barceloneta
Canada
Loredana
P30,448
P35,395 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Arts Barcelona
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region.
Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
P9,425
P10,652 total
Aug 31 - Sep 1
includes taxes & fees
8.6/10 Excellent! (5,151 reviews)
Barcelona Airport Hotel
Hotel Quirinale

Hotel Quirinale

Via Nazionale 7 Rome RM
P12,057
P14,344 total
Aug 30 - Aug 31
includes taxes & fees
8.8/10 Excellent! (1,923 reviews)
Hotel Quirinale
Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
P5,290
P5,819 total
Sep 3 - Sep 4
includes taxes & fees
9.4/10 Exceptional! (1,267 reviews)
Hotel101- Madrid
Still don't see what you're looking for?
See all properties in Mediterranean Region.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
A winding road through a mountainous landscape with the sun setting behind the hills.

Top Mediterranean Region Hotel Reviews

Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower

8/10 Good
"Beautiful place - the check in process is a nightmare - but otherwise the room was nice and comfortable"
Kim 1-night trip
Posted less than an hour ago
Hyatt Regency Barcelona Tower
Nobu Hotel Barcelona

Nobu Hotel Barcelona

10/10 Excellent
"Strategic location"
Mary Ann 2-night trip
Posted 15 hours ago
Nobu Hotel Barcelona
Grand Hyatt Barcelona

Grand Hyatt Barcelona

10/10 Excellent
"Amazing stay."
YESNEIDY 1-night trip
Posted 22 hours ago
Grand Hyatt Barcelona
Titanic Deluxe Golf Belek

Titanic Deluxe Golf Belek

10/10 Excellent
"Everything was amazing, except the WiFi signal and lack of baby changers"
Ihab Hameed Swadi 6-night trip
Posted 3 months ago
Titanic Deluxe Golf Belek

Find out more about Mediterranean Region

Stay in Luxury: 5 Star Hotels in Mediterranean Region

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Mediterranean Region trip. You'll join the multitudes of holidaymakers who have made Mediterranean Region so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Mediterranean Region and indulge in the finer things in life for a while.

5-Star Hotels in Mediterranean Region

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Mediterranean Region are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Mediterranean Region 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Mediterranean Region! Choose one of our Mediterranean Region 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Expedia India is rated 4 stars by Feefo based on 1038 reviews