Southeast Minnesota Hotels

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Southeast Minnesota hotel prices

Tonight
Jun 5 - Jun 6
Tomorrow night
Jun 6 - Jun 7
This weekend
Jun 7 - Jun 9
Next weekend
Jun 14 - Jun 16

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Top 10 trending Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, 608 reviews
"Excellent"
The price is P 6,326
per night
Jul 4 - Jul 5
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Kahler Inn and Suites - Mayo Clinic Area
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, 1,214 reviews
"Nice, quiet, clean rooms. To the Mayo Clinic was all done by Subway. No need to go outside if the weather was bad. It was only about a 5-minute walk, so really convenient."
The price is P 6,819
per night
Jun 7 - Jun 8
Kahler Inn and Suites - Mayo Clinic Area
Kahler Grand Hotel
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, 1,015 reviews
"Extremely close to Mayo Clinic Excellent staff"
The price is P 8,752
per night
Jun 8 - Jun 9
Kahler Grand Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, 561 reviews
"Staff was great on check in "
The price is P 6,520
per night
Jul 2 - Jul 3
Hyatt House Rochester/Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.8 out of 10, Good, 1,005 reviews
"Nice"
The price is P 5,339
per night
Jun 23 - Jun 24
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, 546 reviews
"We loved this property- it was perfect! Parking was so easy, even with their ramp being under construction we could still park in a ramp connecting to the hotel via skyway. Coincidentally, we were across the street from all of the dining and restaurants we wanted to explore making everything so walkable and convenient! We loved our stay in Rochester and this hotel was the perfect place! Very clean, quiet, safe, water available for purchase at the hotel desk which was great!"
The price is P 6,871
per night
Jun 30 - Jul 1
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, 1,005 reviews
"Pond next door, walking paths, shuttle to hospital and many things close by"
The price is P 5,898
per night
Jun 23 - Jun 24
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
St James Hotel, a Historic Hotel of America
Exterior
St James Hotel, a Historic Hotel of America
3.5 star property
9.2 out of 10, Wonderful, 988 reviews
"wonderful weekend getaway spot"
The price is P 9,462
per night
Jun 9 - Jun 10
St James Hotel, a Historic Hotel of America
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
In-room safe, desk, iron/ironing board, free cribs/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very Good, 1,005 reviews
"The room was small, but okay for a single person. The bed was okay, it was clean. Loved the bench above the air conditioner/heater. The breakfast was standard cold and hot items, but not much for sitting, so you may need to eat in your room. The down fall was I could hear a TV going in the next room and in the other room, hear a phone alarm going off."
The price is P 3,944
per night
Jun 9 - Jun 10
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Hampton Inn Rochester-South
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, 1,009 reviews
"Staff is awesome!! Room smelled wonderful but it is a weird layout. Only negative was the bed. Felt like the springs were eating me all night. "
The price is P 5,383
per night
Jul 5 - Jul 6
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Blackout drapes, soundproofing, iron/ironing board, free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very Good, 395 reviews
"Very helpful "
The price is P 5,192
per night
Jun 10 - Jun 11
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Express Suites Riverport Inn & Suites
Lobby
Express Suites Riverport Inn & Suites
3.0 star property
8.6 out of 10, Excellent, 1,006 reviews
"Had to get another room cuz the tub wouldn't drain. Staff was very nice and helpful. Easy room change. Construction going on...but overall pleased. 🙂"
The price is P 6,460
per night
Jun 9 - Jun 10
Express Suites Riverport Inn & Suites
Residence Inn by Marriott Rochester Mayo Clinic Area South
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, 87 reviews
"Wonderful rooms and accommodations. "
The price is P 6,697
per night
Jun 22 - Jun 23
Residence Inn by Marriott Rochester Mayo Clinic Area South
Days Inn by Wyndham Winona
In-room safe, desk, blackout drapes, iron/ironing board
Days Inn by Wyndham Winona
2.0 star property
7.8 out of 10, Good, 1,003 reviews
"They could have saved the breakfast. Very limited but they did leave it open until late morning."
The price is P 4,111
per night
Jun 9 - Jun 10
Days Inn by Wyndham Winona
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, 620 reviews
"Great place to stay. Accessible to everything."
The price is P 6,447
per night
Jun 14 - Jun 15
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
The Plaza Hotel & Suites Winona
Lunch and dinner served, American cuisine
The Plaza Hotel & Suites Winona
3.0 star property
9.0 out of 10, Wonderful, 972 reviews
"The front desk staff were helpful and friendly."
The price is P 8,517
per night
Jun 9 - Jun 10
The Plaza Hotel & Suites Winona
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, 284 reviews
"Super nice and clean rooms with a lot of space"
The price is P 6,938
per night
Jun 14 - Jun 15
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Nichols Inn of Red Wing
Lobby
Nichols Inn of Red Wing
2.5 star property
9.0 out of 10, Wonderful, 666 reviews
"Clean and easy "
The price is P 4,863
per night
Jun 9 - Jun 10
Nichols Inn of Red Wing
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, 613 reviews
"Everything was very well done, all of the staff very friendlyand eager to please.. Breakfast was quite delicious. "
The price is P 6,018
per night
Jul 5 - Jul 6
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Home2 Suites by Hilton Rochester Mayo Clinic Area
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, 629 reviews
"It’s close to the shopping center, Mayo Clinic and restaurants. The rooms are spacious. "
The price is P 7,447
per night
Jun 13 - Jun 14
Home2 Suites by Hilton Rochester Mayo Clinic Area
Don't see what you're looking for?
See all available properties in Southeast Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southeast Minnesota

Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Find hotels in Downtown Rochester

More cheap stays in Southeast Minnesota

Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd, Winona, MN
The price is P3,583 per night from Jul 2 to Jul 3
P3,583
per night
2 Jul - 3 Jul
7.4/10 Good! (872 reviews)

Near an Attraction

Image for Minnesota Zoo

Minnesota Zoo

Let the beautiful inhabitants of this interactive zoo charm and entertain the whole family for hours on end.

See properties
Minnesota Zoo

Southeast Minnesota hotels information

Number of reviews
5,354
Accommodation
883 hotels
Lowest Price
P3,583
Highest Price
P9,462

Recent Reviews in Southeast Minnesota
Expedia verified reviews

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

5/5 Excellent
"Nice, quiet, clean rooms. To the Mayo Clinic was all done by Subway. No need to go outside if the weather was bad. It was only about a 5-minute walk, so really convenient."
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
Posted 8 hours ago
Kahler Inn and Suites - Mayo Clinic Area