Hotels in Wykoff from P4,122 for 2026 - Fully Refundable Options

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Our top choices for Wykoff hotels

A lobby with leather sofas, a reception desk, a clock, and a map of the museum.

A lobby with a fireplace, leather seating, a television, and a large window.

A large, single-story motel with a covered parking area and a grassy lawn.

A breakfast room with wooden tables and chairs, a coffee machine, and a view of the outdoors.

1. Americas Best Value Inn & Suites Spring Valley

Spring Valley

Lori

P5,336

P5,890 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk, a chair, and a lamp.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

A swimming pool with a capacity sign, a lifeguard warning sign, and a spa rules sign.

A living room with a brick fireplace, two armchairs with decorative pillows, and a framed map on the wall.

2. Country Trails Inn & Suites

Preston

Jeannie

P7,923

P8,745 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A modern living room with a sofa, two armchairs, a coffee table, and a large window offering a view of the outdoors.

A laundry area with two Whirlpool washers and a dryer, a wooden shelf above, and a white ceiling.

A reception desk with a wooden finish, a large illuminated 'C' sign, and a modern light fixture on the ceiling.

3. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Phil

P5,430

P6,251 total

includes taxes & fees

Oct 10 - Oct 11

A modern hotel lobby with a reception desk, seating area, and a dining space.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

A hotel room with a bed, desk, chair, and a bathroom.

4. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Melissa

P6,264

P7,211 total

includes taxes & fees

Oct 11 - Oct 12

A multi-story building with a balcony, surrounded by various potted plants and flowers.

An outdoor patio with tables and chairs, green umbrellas, and a wooden deck.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

A bedroom with a four-poster bed, a sofa, a desk, and a fireplace.

5. Green Gables Inn

Lanesboro

Sandra

P5,288

P5,678 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A spacious living area with a high ceiling, wooden beams, a blue armchair, a sofa, and a glass coffee table.

A bedroom with a large bed, a bathtub, a wooden rocking chair, and a desk with a lamp.

A rustic bar area with wooden beams, a wooden counter, and sacks of grain.

6. Stone Mill Hotel & Suites

Lanesboro

Jenifer

P6,577

P7,063 total

includes taxes & fees

Nov 3 - Nov 4

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A hotel room with a large bed, a desk, a chair, and a kitchenette.

A small, well-organized pantry with shelves stocked with snacks and beverages.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

7. Spark by Hilton Rochester South

Rochester

Stanton

P5,354

P6,163 total

includes taxes & fees

Oct 13 - Oct 14

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

8. Hampton Inn Rochester-South

Rochester

dennis

P6,626

P7,628 total

includes taxes & fees

Oct 25 - Oct 26

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.

9. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Kathryn

P4,473

P5,149 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern indoor pool area with lounge chairs and a pool.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

10. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Kathy

P7,392

P8,509 total

includes taxes & fees

Oct 23 - Oct 24

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

A modern restaurant with a counter, seating area, and a TV screen.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

11. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

howard

P7,653

P8,811 total

includes taxes & fees

Oct 24 - Oct 25

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern lounge area with seating, a fireplace, and a bar area.

12. Residence Inn by Marriott Rochester Mayo Clinic Area South

Rochester

Chee

P8,286

P9,540 total

includes taxes & fees

Oct 17 - Oct 18

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

A hotel room with a bed, bedside table, and a window with curtains.

13. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Hafsa

P8,582

P9,880 total

includes taxes & fees

Oct 23 - Oct 24

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

A bar with wooden stools and a neon sign.

An indoor swimming pool with a slide, seating area, and a large frog statue.

14. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Jeanne

P4,571

P5,263 total

includes taxes & fees

Oct 25 - Oct 26

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A reception area with a curved counter, ceiling lights, and a potted plant.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

15. Brentwood Inn & Suites

Downtown Rochester

Daniel

P5,873

P6,761 total

includes taxes & fees

Oct 29 - Oct 30

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

16. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester

Richard

P7,155

P8,237 total

includes taxes & fees

Oct 23 - Oct 24

A reception desk with a wooden finish, a glass partition, and a blue wall with climbing plants.

A hotel with a parking lot, a yellow food truck, and several cars parked.

A staircase with patterned carpet and wooden handrails leading to a door marked with the number 201.

A hotel room with two beds, each with white linens and patterned bedspreads. There are bedside tables with lamps, a desk with a chair, and a wall-mounted TV.

17. America's Stay Inn Stewartville

Stewartville

Robert

P3,664

P4,122 total

includes taxes & fees

Nov 4 - Nov 5

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A compact laundry area with a washing machine, dryer, and a water fountain.

18. Econo Lodge Mayo Clinic Area

Rochester

Ashley

P4,411

P5,078 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A modern conference room with a long table, multiple chairs, and a wooden partition.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

A hotel reception desk with a modern design, a clock, and a digital screen.

19. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park

Jackie

P6,441

P7,415 total

includes taxes & fees

Oct 17 - Oct 18

A modern indoor patio with a fire feature, seating, and large windows.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

20. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

Rici

P7,408

P9,376 total

includes taxes & fees

Nov 6 - Nov 7

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Stay near popular Wykoff attractions

Ed's Museum

You can spend time exploring the galleries in Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area.

See properties

Top Wykoff Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The room was very clean. Staff were kind and pleasant upon check in."

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"Good location for access to restuarants, clinic, St. Mary's. Nice room and helpful staff."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"The location connected to Mayo and the underground parking for only $15/night can not be beat. So convenient. The room itself was good, roomy, comfy bed. It is an older hotel with older decor but I’m not here for an extravagant vacation I need convenience. And the staff was helpful with needing a late checkout and extending our time in their parking garage since we had a late appointment. Oh and the attached Chinese restaurant is Amazing!!"

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Absolutely perfect hotel, especially if you are traveling back and forth to St. Mary’s campus for Mayo. Great breakfast, free laundry, great shower, comfy bed. Best you could get in these circumstances away from home. Thank you!"

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Staff was good, rooms were clean but needing some updates"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Excellent location. Great shuttle service to mayo gonna. No working wifi in my room but other than that was fine."

Aspen Select

10/10 Excellent

"Very close to the North entrance of St. Mary's. Construction is there but still very convenient."

Brentwood Inn & Suites

10/10 Excellent

"Staff was very helpful and kind. Desk chair worn and could use a replacement-normally would not care but was working remote while there. Wi-Fi great"

More cheap stays in Wykoff

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN

P3,636

P4,186 total

Oct 19 - Oct 20

includes taxes & fees

7.6/10 Good! (89 reviews)

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

P4,473

P5,149 total

Oct 8 - Oct 9

includes taxes & fees

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN

P5,430

P6,251 total

Oct 10 - Oct 11

includes taxes & fees

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

P5,873

P6,761 total

Oct 29 - Oct 30

includes taxes & fees

8.8/10 Excellent! (1,000 reviews)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

P6,213

P7,153 total

Oct 11 - Oct 12

includes taxes & fees

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN

P6,264

P7,211 total

Oct 11 - Oct 12

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Wykoff?

Located 22.4 mi (36.1 km) from the heart of Wykoff, AmericInn by Wyndham Rochester Near Mayo Clinic is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Wykoff.

If I need to cancel my hotel reservation in Wykoff, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.

How is it staying in Wykoff?

Visitors can enjoy all that Wykoff has to offer including its museums. There are 321 hotels and other accommodations in the surrounding area. Find out more about Wykoff.

What are the top places to visit in Wykoff?

A favorite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Check out what more to see and do in Expedia's Wykoff guide.

What's the weather like in Wykoff?

The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 22°F. The snowiest months in Wykoff are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.

Wykoff Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Wykoff

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Wykoff hotels

1. Americas Best Value Inn & Suites Spring Valley

2. Country Trails Inn & Suites

3. Comfort Inn & Suites Rochester South Mayo Clinic

4. Holiday Inn Express Rochester South - Mayo Area by IHG

5. Green Gables Inn

6. Stone Mill Hotel & Suites

7. Spark by Hilton Rochester South

8. Hampton Inn Rochester-South

9. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10. Hyatt House Rochester/Mayo Clinic Area

11. Home2 Suites by Hilton Rochester Mayo Clinic Area

12. Residence Inn by Marriott Rochester Mayo Clinic Area South

13. TownePlace Suites by Marriott Rochester Mayo Clinic Area

14. AmericInn by Wyndham Rochester Near Mayo Clinic

15. Brentwood Inn & Suites

16. Hilton Garden Inn Rochester Downtown, MN

17. America's Stay Inn Stewartville

18. Econo Lodge Mayo Clinic Area

19. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

20. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Stay near popular Wykoff attractions

Ed's Museum

Top Wykoff Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

AmericInn by Wyndham Rochester Near Mayo Clinic

Kahler Inn and Suites - Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Aspen Select

Brentwood Inn & Suites

More cheap stays in Wykoff

Birch Hill Suite Rochester – Med City

Med City Inn & Suites - Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Brentwood Inn & Suites

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Holiday Inn Express Rochester South - Mayo Area by IHG

Frequently asked questions

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