Photo by Bill Dillard

Search Motels in Southeast Missouri

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Our top choices for Southeast Missouri motels

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1005)
"It was a nice stay."
United States
Rebecca
The price is P4,465
P4,888 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Motel 6 Poplar Bluff, MO

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very Good, (165)
"The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!"
United States
Thad
The price is P5,445
P5,893 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Current River Inn

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very Good, (612)
"Clean, friendly staff, quiet"
United States
Stacy
The price is P3,097
P3,525 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Super 8 by Wyndham Farmington

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (732)
"Friendly sta"
United States
Melissa
New Orleans Inn Portageville

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (426)
"The staff member Tim was very friendly and nice. "
United States
Julie
The price is P3,812
P4,125 total
includes taxes & fees
Jan 30 - Jan 31, 2026
Town House Inn

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (297)
"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
The price is P4,576
P4,998 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Madison Inn Lodge

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is P3,144
P3,740 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Country Yard Inn and Suite

Black River Motel and Restaurant

Black River Motel and Restaurant
2.0 star property
Lesterville
8.4 out of 10, Very Good, (34)
"This has been a great place to stay when we are traveling through Reynolds County MO."
United States
Michael
The price is P7,578
P8,012 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Black River Motel and Restaurant

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is P3,558
P3,949 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Eagle Inn Charleston

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is P3,235
P3,779 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Town House Inn Cape Giradreau

Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
2.0 star property
Bonne Terre
7.0 out of 10, Good, (27)
"Clean, was perfect for my one night stay in the area"
United States
Dave
The price is P3,494
P3,821 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Motel 6 Bonne Terre, MO

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (253)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
The price is P3,499
P3,929 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Econo Lodge Dexter

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (540)
"The room was spacious and very clean. The parking was free and close to the entrance, excellent water pressure for the shower, and the staff was friendly and professional."
United States
Raymond
The price is P2,950
P3,226 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Super 8 by Wyndham Bonne Terre

OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (134)
"We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful."
United States
Albert
The price is P2,879
P3,585 total
includes taxes & fees
Jan 12 - Jan 13, 2026
OYO Hickory House Inn

Rosener's Inn and banquet center

Rosener's Inn and banquet center
2.0 star property
Park Hills
5.0 out of 10, (48)
"Not the cleanest place I've ever stayed, but you get what you pay for. If you expect pristine rooms, comfortable beds, clean towels, blankets and sheets, coffee makers, refrigerators and microwaves for $50 a night, you will be terribly disappointed. There is a reason the rooms aren't $150 per night. "
United States
Brock
The price is P4,235
P4,631 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Rosener's Inn and banquet center

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (943)
"Always a great stay"
United States
Steven
The price is P3,900
P4,465 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Super 8 by Wyndham Perryville

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (615)
"Staff was great! Room was nice. "
United States
Lana
The price is P3,653
P4,054 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
2.0 star property
Potosi
7.0 out of 10, Good, (379)
" Our stay was good. Employees were nice, room was clean, "
United States
Kenneth
The price is P3,250
P3,551 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Super 8 by Wyndham Potosi

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (628)
"The lady at the front was very nice. "
United States
Travis
The price is P3,346
P3,780 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Super 8 by Wyndham Poplar Bluff Missouri

Mammoth Spring Lodge Motel

Mammoth Spring Lodge Motel
2.0 star property
Thayer
8.0 out of 10, Very Good, (404)
"The room was spotless and the staff was very nice. I would stay again and again."
United States
Stacy
The price is P5,816
P6,543 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Mammoth Spring Lodge Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Missouri Hotel Reviews

Find out more about Southeast Missouri

Southeast Missouri Motels information

Number of reviews
7,613
Accommodation
26 Motels
Lowest Price
P3,226
Highest Price
P8,012

Explore a world of travel with Expedia