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Southeast Missouri Hotels

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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,007 reviews)
"Great place!"
United States
Jennifer
The price is P6,818
P7,839 total
includes taxes & fees
Jul 22 - Jul 23
Drury Inn & Suites Sikeston, MO

Deerfield Inn & Suites Steele Near Blytheville I 55

Deerfield Inn & Suites Steele Near Blytheville I 55
2.5 star property
Steele
8.8 out of 10, Excellent, (3 reviews)
"Love it, very peaceful! What else want from me"
United States
Mary
The price is P3,133
P3,625 total
includes taxes & fees
Jul 8 - Jul 9
Deerfield Inn & Suites Steele Near Blytheville I 55

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,013 reviews)
"Wonderful room and food offerings were extra thoughtful."
United States
Jonna
The price is P6,764
P7,631 total
includes taxes & fees
Jul 26 - Jul 27
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (794 reviews)
"Beautiful hotel at a very good price."
United States
Sheldon
The price is P5,691
P6,159 total
includes taxes & fees
Jul 23 - Jul 24
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,008 reviews)
"Great hotel"
United States
mason
The price is P4,729
P5,335 total
includes taxes & fees
Jul 29 - Jul 30
Pear Tree Inn Cape Girardeau West

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
2.0 star property
Potosi
7.2 out of 10, Good, (404 reviews)
"Owner was very kind. He knew we were running a long trail race the next morning and got up an hour early so he could make coffee and put out breakfast for us at 5:30 am. We were so grateful!"
United States
Julie
The price is P3,576
P3,906 total
includes taxes & fees
Jul 19 - Jul 20
Super 8 by Wyndham Potosi

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (474 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is P6,450
P7,303 total
includes taxes & fees
Jul 26 - Jul 27
Holiday Inn Express & Suites Sikeston Southwest by IHG

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,003 reviews)
"Clean room and convenient location."
United States
Morgan
The price is P4,853
P5,435 total
includes taxes & fees
Jul 8 - Jul 9
Motel 6 Poplar Bluff, MO

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (783 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is P3,483
P3,761 total
includes taxes & fees
Aug 2 - Aug 3
New Orleans Inn Portageville

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (929 reviews)
"Hotel Staff was very friendly!"
United States
Alice
The price is P6,204
P7,009 total
includes taxes & fees
Jul 12 - Jul 13
Fairfield Inn & Suites by Marriott Poplar Bluff

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,002 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
United States
William
The price is P5,344
P5,650 total
includes taxes & fees
Jul 12 - Jul 13
Drury Inn & Suites Jackson MO

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (371 reviews)
"Simple no frills hotel that we've stayed at a few times while traveling."
United States
Monica
The price is P6,136
P6,653 total
includes taxes & fees
Jul 9 - Jul 10
Honeysuckle Inn - Mountain View

Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.4 out of 10, Exceptional, (319 reviews)
"Breakfast was good and rooms were clean"
United States
Shannon
The price is P7,574
P8,273 total
includes taxes & fees
Jul 8 - Jul 9
Shepherd Mountain Inn

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.6 out of 10, Excellent, (573 reviews)
"Rooms are very clean. Easy and fast check in"
United States
Kanyia
The price is P4,960
P5,641 total
includes taxes & fees
Jul 9 - Jul 10
The Farmstead Hotel

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (587 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is P6,799
P7,699 total
includes taxes & fees
Jul 18 - Jul 19
Hampton Inn Sikeston

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very Good, (185 reviews)
"This was the cutest little place to stay. The people are friendly, room was clean, and it was safe. I would stay here again. "
United States
Jennifer
The price is P6,690
P7,239 total
includes taxes & fees
Jul 8 - Jul 9
Current River Inn

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Staff and breakfast were excellent."
United States
James
The price is P6,765
P7,632 total
includes taxes & fees
Jul 16 - Jul 17
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (646 reviews)
"Clean rooms,"
United States
Karl
The price is P3,655
P4,056 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Charleston/Sikeston East MO

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (97 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is P6,757
P7,651 total
includes taxes & fees
Jul 26 - Jul 27
Fairfield Inn & Suites by Marriott Sikeston

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (305 reviews)
"Rooms were clean! Beds were comfortable, and the staff were very accommodating."
United States
Ashley
The price is P5,376
P5,872 total
includes taxes & fees
Jul 9 - Jul 10
Madison Inn Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southeast Missouri

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Stay near popular Southeast Missouri attractions

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to Walnut Hollow Lake.

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

  • Outdoor Adventures: Southeast Missouri is perfect for thrill-seekers, offering numerous hiking trails and scenic parks.
  • Family-Friendly Activities: The region is ideal for families, with recreational options and charming towns to explore together.
  • Local Craft Beverages: Enjoy brewery tours that showcase the region's unique craft drinks and local flavours.
  • Educational Experiences: Campus tours at Southeast Missouri State University enrich your visit with cultural insights.
  • Picturesque Landscapes: Discover stunning natural beauty and friendly locals, enhancing your holiday experience.

Find great hotels near Southeast Missouri

Discover a variety of hotel accommodations in Southeast Missouri, ideal for every type of traveller. Whether you're seeking a comfortable lodge for a family getaway, a business-friendly hotel, or an adventurous retreat, the region offers a selection of top-rated establishments. With options close to attractions and comprehensive reviews available, planning your perfect stay in Southeast Missouri has never been easier.

  • Madison Inn Lodge: A welcoming motel that caters to both business travellers and pet owners. Located 25.7km from Southeast Missouri, this lodge ensures a comfortable stay with its pet-friendly policies, allowing certain pets onsite. Guests can appreciate the convenience of amenities designed for working professionals while enjoying the laid-back atmosphere perfect for relaxation. Madison Inn Lodge is a great choice for those seeking a practical yet cosy lodging experience, where pets are treated like family.
  • Shepherd Mountain Inn: A charming hotel situated 33.8km away from Southeast Missouri, ideal for business-focused travellers. Shepherd Mountain Inn combines comfort with functionality, offering well-appointed rooms and essential amenities to support your work-related needs. Its professional ambiance, coupled with a friendly staff, makes it a reliable choice for those needing a peaceful environment to unwind after a productive day. This hotel serves as a solid base for exploring the nearby attractions while attending to business commitments.
  • Alpaca Farm Stay: Nestled just 12.9km from Southeast Missouri, Alpaca Farm Stay is a unique lodge offering a delightful blend of adventure and romance for families and couples alike. This property features a plethora of outdoor activities, including kayaking, swimming, and rafting, ensuring an adventurous getaway. Families will appreciate the shared playground for children, while couples can indulge in specially crafted romance packages. With breathtaking mountain and lake views available from bookable units, Alpaca Farm Stay is perfect for those seeking a memorable, nature-filled escape.

Where to stay near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor adventure and family-friendly experiences. Explore the scenic beauty of the region, where leisurely strolls reveal picturesque landscapes and friendly locals enhance your stay. The area is perfect for a relaxing retreat, with convenient locations for families to enjoy recreation and bonding time. Whether you're hiking trails or visiting charming towns, Southeast Missouri promises a memorable getaway filled with warm atmospheres and unforgettable experiences.

  • Central Fredericktown: A quaint village located 16.1km from Southeast Missouri, Central Fredericktown offers a charming blend of outdoor, family, and city-themed experiences. The village attracts visitors throughout the year, with peak arrivals from June to August. Here, you can enjoy recreational areas perfect for family outings, educational opportunities, and a shopping mall centre. Local highlights include a lovely park, an urban park ideal for leisurely strolls, and a history museum that showcases the area’s rich heritage.
  • Annapolis: Situated 22.5km from Southeast Missouri, Annapolis is a vibrant city renowned for its outdoor scenery and adventurous spirit. The city's visitor numbers peak during the summer months, particularly from June to July and again in September. Visitors can explore recreational areas and enjoy various entertainment options at the arena. Notable attractions include a nearby national state park, a picturesque river, and expansive parks that invite exploration and relaxation amidst nature.
  • Des Arc: Located 17.7km away from Southeast Missouri, Des Arc is a city that thrives on its seasonal visitor influx, peaking during the summer months of June to August. Here, adventure seekers can explore recreational areas, enjoy a thrilling day at the water park, or catch a show at the local arena entertainment facility. The surrounding natural beauty is highlighted by a national state park, a serene lake, and a winding river, making it an ideal destination for those looking to immerse themselves in the great outdoors.

Things to do near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor adventures and educational experiences, perfect for a memorable holiday. Visitors can enjoy campus tours, partake in various outdoor activities, and witness thrilling sports tournaments. Additionally, brewery tours provide a taste of local craft beverages, while educational experiences enrich the trip. With its scenic beauty and recreational areas, Southeast Missouri is an ideal destination for those seeking adventure and relaxation.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a mix of local goods and antiques. Additionally, the Farmington Mineral Area Shopping Center, 48.3km away, features a variety of shops and entertainment options suitable for families.

Recreation

At Crane Lake Recreation Area, immerse yourself in serene surroundings while enjoying peaceful walks and nature meditation. The Silver Mine Recreation Area offers a tranquil escape with picturesque trails for relaxation. For sports enthusiasts, Arcadia Valley Golf Club provides an invigorating outdoor experience amidst lush greens.

Adventure

Explore Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri. Experience thrilling biking routes and scenic hiking trails that showcase the region's natural beauty, all while enjoying the great outdoors in an adventurous atmosphere.

Nightlife

Experience the vibrant nightlife at The Blue Note, where you can enjoy live music and a lively atmosphere. For a more laid-back evening, visit the Catfish Kitchen for delightful local brews and a friendly vibe. Don’t miss the chance to dance at The 9th Street Dance Club for a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

For a budget-friendly trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays typically offer the best hotel rates, while Saturdays are the most expensive. Utilise Expedia’s search tool to find affordable hotels by sorting results from lowest to highest price, and consider eco-certified options for sustainable stays. To save further, explore package deals that combine hotels, flights, and activities. Don’t forget to check for hotel deals and compare room rates to secure the best rates available.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and various other preferences. You can arrange your search results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Furthermore, you have the option to refine your choices by hotel type—by selecting the Eco-certified filter, for instance, you'll be presented with sustainable and environmentally friendly hotels ready for booking.
  • Consider bundling your trip: You can save money by combining your Southeast Missouri hotel reservation with your flights and activities through an Expedia package.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor escapades and scenic beauty, perfect for adventure-seeking tourists. Key attractions include urban parks, national state parks, and historic civic government buildings, providing eco-friendly and family-oriented experiences. Visitors can also explore the nearby Southeast Missouri State University and other local attractions, ensuring a memorable stay in this charming region.

  • Sam A. Baker State Park: Nestled 12.9km from Southeast Missouri, this stunning state park offers breathtaking scenery and outdoor adventures. Enjoy hiking trails, picnic spots, and opportunities for wildlife viewing amidst the natural beauty of the area.
  • Walnut Hollow Lake: Located 20.9km away, Walnut Hollow Lake is perfect for a romantic day out. With its sandy beach and picturesque surroundings, it's an ideal spot for swimming, sunbathing, and enjoying peaceful moments by the water.
  • K Bridge Recreation Area: Situated 27.4km from Southeast Missouri, this urban park is family-friendly, featuring open spaces for picnics, play areas for children, and walking trails, making it a great place for a city escape with loved ones.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowSlightly Low
February38.1°F (3.4000000000000004°C)Light RainMostly SunnySlightly LowAverage
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.700000000000003°C)Light RainMostly SunnySlightly HighSlightly High
July79.2°F (26.200000000000003°C)Light RainMostly SunnySlightly HighAverage
August77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December39.4°F (4.1000000000000005°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Southeast Missouri

For your visit to Southeast Missouri, you can fly into several major airports. St. Louis Lambert International Airport (STL) is situated 154.5km away and features nearby hotels such as The Ritz-Carlton (11.3km), the Royal Sonesta Chase Park Plaza (14.5km), and Ameristar Casino Resort and Spa (11.3km). Fort Leonard Wood Regional Airport (TBN) is also 154.5km distant, with options like Z Loft Extended Stay Hotel, Quality Inn St. Robert, and Holiday Inn Express, all within 9.7km. Additionally, Paducah Barkley Regional Airport (PAH) is 152.9km away, offering hotels like The Respite Bed and Breakfast (14.5km) and Drury Inn (8.0km).

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