Hotels in Southeast Missouri from P3,891 for 2026 - Fully Refundable Options

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Go beyond your typical stay in Southeast Missouri

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Cottage

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Our top choices for Southeast Missouri hotels

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.

A building with a red awning labeled "Shepherd Mountain Inn."

A compact kitchen with wooden cabinets, a stainless steel refrigerator, and a microwave.

A bathroom with a white sink, a large mirror, a hairdryer, a coffee maker, and a microwave.

1. Shepherd Mountain Inn

Ironton

Michael

P7,713

P8,425 total

includes taxes & fees

Oct 6 - Oct 7

A motel with a covered entrance, a flag, and a phone number.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

2. Madison Inn Lodge

Fredericktown

Bawan

P5,066

P5,533 total

includes taxes & fees

Nov 3 - Nov 4

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

3. Hampton Inn & Suites By Hilton Festus

Festus

Abram

P5,591

P6,393 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

A hotel lobby with a seating area, a reception desk, and a bar.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

4. Holiday Inn Express & Suites Perryville by IHG

Perryville

Lisa

P6,318

P7,232 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.

A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

5. Crown Pointe Lodge, BW Signature Collection

Farmington

Stephanie

P6,859

P7,843 total

includes taxes & fees

Oct 14 - Oct 15

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A corner market with a refrigerated display case and a pantry area.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

6. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Nancy

P6,327

P7,148 total

includes taxes & fees

Oct 11 - Oct 12

A modern kitchen with a coffee machine, a refrigerator, and a microwave.

A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.

A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.

7. Super 8 by Wyndham Farmington

Farmington

Marisa

P3,722

P4,256 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a reception desk, seating area, and large windows.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

8. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Dean

P5,879

P6,642 total

includes taxes & fees

Oct 18 - Oct 19

A living room with a blue wall, a fireplace, a sofa, and a chair.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

A bar area with stools and a counter where a bartender is serving drinks.

9. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

P6,577

P7,159 total

includes taxes & fees

Oct 6 - Oct 7

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.

A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.

10. Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

Joseph

P3,403

P3,891 total

includes taxes & fees

Nov 1 - Nov 2

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

11. Hampton Inn Poplar Bluff

Poplar Bluff

Rhonda

P5,689

P6,370 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

12. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

P6,327

P7,138 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a desk, a chair, a TV, and a lamp.

A two-story building with a green roof and a large circular sign that reads "Port David Restaurant".

A hotel room with a television, a desk, a chair, a dresser, a radiator, and a bathroom visible through an open door.

A reception desk with a woman standing behind it, a man with a suitcase, and another person standing to the left.

13. Fort Davidson Hotel

Ironton

richard

P7,506

P8,199 total

includes taxes & fees

Oct 27 - Oct 28

A hotel room with a bed, a sofa, a desk, and a chair.

An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.

14. Holiday Inn Express & Suites Farmington by IHG

Farmington

Sheila

P7,631

P8,726 total

includes taxes & fees

Oct 11 - Oct 12

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

A swimming pool with lounge chairs and a view of the night sky.

A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.

15. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

Lisa-Marie

P5,264

P6,019 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

16. The Riverview

Cape Girardeau

Alyssa

P7,150

P8,066 total

includes taxes & fees

Oct 7 - Oct 8

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

17. Super 8 by Wyndham Perryville

Perryville

paulette

P4,307

P4,930 total

includes taxes & fees

Oct 14 - Oct 15

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

18. Drury Inn & Suites Jackson MO

Jackson

Thomas

P5,004

P5,290 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

19. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

P6,255

P7,056 total

includes taxes & fees

Oct 11 - Oct 12

A red wooden mill with a small bridge over a flowing river, surrounded by lush greenery.

A playground with a slide, climbing structures, and a small shelter.

A dining area with a round table and chairs, large windows with curtains, and a whiteboard on the wall.

A grassy field with trees in the background.

20. Honeysuckle Inn - Mountain View

Mountain View

Joanne

P6,193

P6,714 total

includes taxes & fees

Oct 6 - Oct 7

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Vacation Rentals in Southeast Missouri

Cabin

A view through a window with a stone wall and a wooden structure in the background.

A compact kitchen with wooden cabinets, a dishwasher, a refrigerator, and a coffee maker.

Sam A Baker State Park

Patterson

"Pet friendly, great staff. "

Cabin

A bedroom with a bed, a wooden headboard, a window with a view of greenery, and a tray with breakfast items.

A rustic cabin with a wooden exterior, a small deck, and a picnic table.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

"The stay here gets better every time."

Aparthotel

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

A hallway with exposed brick walls, wooden flooring, and a white door.

Urban Lofts

Perryville

"Beautiful place and staff was amazing!"

Aparthotel

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

The Atrium - A Boutique Hotel

Perryville

"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."

Cottage

A dining area with a checkered tablecloth, wooden chairs, and a red rug.

An outdoor patio with a table and chairs, a grill, and a large umbrella.

A two-story house with a red exterior, a front porch, and a well-maintained lawn.

A swimming pool with a wooden deck, surrounded by a white picket fence, and featuring colorful umbrellas.

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

Ironton

"Stroller, pack n play and high chair. This was amazing "

Vacation Home

A wooden deck with two Adirondack chairs and a hammock.

A bedroom with a large bed, wooden ceiling, and a view of the outdoors.

A spacious living room with a wooden ceiling, a fireplace, and a television.

A spacious living room with a wooden ceiling, a ceiling fan, a sofa set, a coffee table, and a large window offering a view of the outdoors.

Tiny Houses of French Village

French Village

"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "

Cabin

A calm lake with a wooden dock and a forested island in the distance.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

A bedroom with a wooden bed, a bench, and a window.

Lake Wappapello

Williamsville

"Pet friendly. Family-friendly "

Cottage

A bedroom with a large bed, a sofa, a wooden wardrobe, and a ceiling fan.

A kitchen with wooden cabinets, a central island, and a dining area with a table set for four.

A single-story house with a front porch, a stone foundation, and a well-maintained lawn.

A covered porch with yellow chairs, a bench, and a small table.

Walk to Dtwn: Ironton Home in Historic District

Ironton

"Clean and comfortable "

Cottage

A cozy cabin interior with a wooden interior, a fireplace, a television, and a comfortable seating area.

A wooden deck leading to a house with a wooden door and a small porch area.

Walk to Current River: Ozarks Adventure Home!

Van Buren

"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."

Cottage

A spacious living room with a high wooden ceiling, two sofas, a coffee table, a TV, and a bookshelf.

A bedroom with a bed, two bedside tables, a dresser, a ceiling fan, and a window with curtains.

A dining area with a glass table and chairs, wooden flooring, and large windows.

A red house with a wooden deck, large sliding glass doors, and a chimney.

Cozy Belgrade Cottage w/ Wood-burning Stove!

Belgrade

Cottage

A bedroom with a bed, nightstand, lamp, and curtains.

A kitchen with granite countertops, white cabinets, a coffee maker, a kettle, and a sink.

A living room with a sofa, coffee table, TV stand, and ceiling fan.

A single-story house with a front porch, a small front yard, and a red roof.

Cottage w/ Yard, Walk to Historic Attractions

Ste Genevieve

"The little blue cottage was very comfortable, clean and close to everything downtown. We parked the car and walked everywhere. It was on a quiet street. The bed was comfy, clean kitchen. We liked the little back yard, for relaxing. "

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Stay near popular Southeast Missouri attractions

A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.

Elephant Rocks State Park

9.6/10 (98 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

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A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

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A sunset over a lake with boats and ducks.

Lake Wappapello

8.8/10 (54 reviews)

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)

Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

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Century Casino Caruthersville

7.0/10 (57 reviews)

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.

Top Southeast Missouri Hotel Reviews

Hampton Inn Poplar Bluff

10/10 Excellent

"Clean room and great bed."

The Riverview

10/10 Excellent

"We were passing through and pleasantly surprised! Clean, well appointed, super friendly staff - everyone seemed happy t work there, and all around great. A real Starbucks in the lobby plus extra security because of the casino in the parking lot were huge plusses. 😊"

Crown Pointe Lodge, BW Signature Collection

10/10 Excellent

"Enjoyed the very clean modern room and the nice view of the golf course. Great place to relax in Farmington"

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Perfect location, beds were awesome & staff were friendly & accommodating!"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"No exhaust fan in the bathroom. Other than that very clean comfortable hotel"

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"The stay here gets better every time."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"Great place"

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"The food & drinks were great & the staff was very friendly. Room was very nice."

Candlewood Suites Cape Girardeau by IHG

8/10 Good

"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, but missing a rather large blood stain on the wall behind the door is disturbing. Thankfully I always travel with Lysol wipes and cleaned it up."

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

P3,403

P3,891 total

Nov 1 - Nov 2

includes taxes & fees

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

P4,147

P4,727 total

Nov 1 - Nov 2

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

P4,503

P5,080 total

Oct 11 - Oct 12

includes taxes & fees

Comfort Inn Festus - St Louis South

1303 Veterans Blvd Festus MO

P4,454

P5,204 total

Nov 1 - Nov 2

includes taxes & fees

7.8/10 Good! (1,003 reviews)

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

P4,942

P5,534 total

Oct 6 - Oct 7

includes taxes & fees

8/10 Very Good! (1,004 reviews)

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

P5,689

P6,370 total

Oct 18 - Oct 19

includes taxes & fees

9.4/10 Exceptional! (966 reviews)

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

Outdoor Adventures: Southeast Missouri is perfect for thrill-seekers, offering numerous hiking trails and scenic parks.
Family-Friendly Activities: The region is ideal for families, with recreational options and charming towns to explore together.
Local Craft Beverages: Enjoy brewery tours that showcase the region's unique craft drinks and local flavours.
Educational Experiences: Campus tours at Southeast Missouri State University enrich your visit with cultural insights.
Picturesque Landscapes: Discover stunning natural beauty and friendly locals, enhancing your holiday experience.

Find great hotels near Southeast Missouri

Discover a variety of hotel accommodations in Southeast Missouri, ideal for every type of traveller. Whether you're seeking a comfortable lodge for a family getaway, a business-friendly hotel, or an adventurous retreat, the region offers a selection of top-rated establishments. With options close to attractions and comprehensive reviews available, planning your perfect stay in Southeast Missouri has never been easier.

Madison Inn Lodge: A welcoming motel that caters to both business travellers and pet owners. Located 25.7km from Southeast Missouri, this lodge ensures a comfortable stay with its pet-friendly policies, allowing certain pets onsite. Guests can appreciate the convenience of amenities designed for working professionals while enjoying the laid-back atmosphere perfect for relaxation. Madison Inn Lodge is a great choice for those seeking a practical yet cosy lodging experience, where pets are treated like family.
Shepherd Mountain Inn: A charming hotel situated 33.8km away from Southeast Missouri, ideal for business-focused travellers. Shepherd Mountain Inn combines comfort with functionality, offering well-appointed rooms and essential amenities to support your work-related needs. Its professional ambiance, coupled with a friendly staff, makes it a reliable choice for those needing a peaceful environment to unwind after a productive day. This hotel serves as a solid base for exploring the nearby attractions while attending to business commitments.
Alpaca Farm Stay: Nestled just 12.9km from Southeast Missouri, Alpaca Farm Stay is a unique lodge offering a delightful blend of adventure and romance for families and couples alike. This property features a plethora of outdoor activities, including kayaking, swimming, and rafting, ensuring an adventurous getaway. Families will appreciate the shared playground for children, while couples can indulge in specially crafted romance packages. With breathtaking mountain and lake views available from bookable units, Alpaca Farm Stay is perfect for those seeking a memorable, nature-filled escape.

Where to stay near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor adventure and family-friendly experiences. Explore the scenic beauty of the region, where leisurely strolls reveal picturesque landscapes and friendly locals enhance your stay. The area is perfect for a relaxing retreat, with convenient locations for families to enjoy recreation and bonding time. Whether you're hiking trails or visiting charming towns, Southeast Missouri promises a memorable getaway filled with warm atmospheres and unforgettable experiences.

Central Fredericktown: A quaint village located 16.1km from Southeast Missouri, Central Fredericktown offers a charming blend of outdoor, family, and city-themed experiences. The village attracts visitors throughout the year, with peak arrivals from June to August. Here, you can enjoy recreational areas perfect for family outings, educational opportunities, and a shopping mall centre. Local highlights include a lovely park, an urban park ideal for leisurely strolls, and a history museum that showcases the area’s rich heritage.
Annapolis: Situated 22.5km from Southeast Missouri, Annapolis is a vibrant city renowned for its outdoor scenery and adventurous spirit. The city's visitor numbers peak during the summer months, particularly from June to July and again in September. Visitors can explore recreational areas and enjoy various entertainment options at the arena. Notable attractions include a nearby national state park, a picturesque river, and expansive parks that invite exploration and relaxation amidst nature.
Des Arc: Located 17.7km away from Southeast Missouri, Des Arc is a city that thrives on its seasonal visitor influx, peaking during the summer months of June to August. Here, adventure seekers can explore recreational areas, enjoy a thrilling day at the water park, or catch a show at the local arena entertainment facility. The surrounding natural beauty is highlighted by a national state park, a serene lake, and a winding river, making it an ideal destination for those looking to immerse themselves in the great outdoors.

Things to do near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor adventures and educational experiences, perfect for a memorable holiday. Visitors can enjoy campus tours, partake in various outdoor activities, and witness thrilling sports tournaments. Additionally, brewery tours provide a taste of local craft beverages, while educational experiences enrich the trip. With its scenic beauty and recreational areas, Southeast Missouri is an ideal destination for those seeking adventure and relaxation.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a mix of local goods and antiques. Additionally, the Farmington Mineral Area Shopping Center, 48.3km away, features a variety of shops and entertainment options suitable for families.

Recreation

At Crane Lake Recreation Area, immerse yourself in serene surroundings while enjoying peaceful walks and nature meditation. The Silver Mine Recreation Area offers a tranquil escape with picturesque trails for relaxation. For sports enthusiasts, Arcadia Valley Golf Club provides an invigorating outdoor experience amidst lush greens.

Adventure

Explore Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri. Experience thrilling biking routes and scenic hiking trails that showcase the region's natural beauty, all while enjoying the great outdoors in an adventurous atmosphere.

Nightlife

Experience the vibrant nightlife at The Blue Note, where you can enjoy live music and a lively atmosphere. For a more laid-back evening, visit the Catfish Kitchen for delightful local brews and a friendly vibe. Don’t miss the chance to dance at The 9th Street Dance Club for a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

For a budget-friendly trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays typically offer the best hotel rates, while Saturdays are the most expensive. Utilise Expedia’s search tool to find affordable hotels by sorting results from lowest to highest price, and consider eco-certified options for sustainable stays. To save further, explore package deals that combine hotels, flights, and activities. Don’t forget to check for hotel deals and compare room rates to secure the best rates available.

The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and various other preferences. You can arrange your search results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Furthermore, you have the option to refine your choices by hotel type—by selecting the Eco-certified filter, for instance, you'll be presented with sustainable and environmentally friendly hotels ready for booking.
Consider bundling your trip: You can save money by combining your Southeast Missouri hotel reservation with your flights and activities through an Expedia package.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a delightful blend of outdoor escapades and scenic beauty, perfect for adventure-seeking tourists. Key attractions include urban parks, national state parks, and historic civic government buildings, providing eco-friendly and family-oriented experiences. Visitors can also explore the nearby Southeast Missouri State University and other local attractions, ensuring a memorable stay in this charming region.

Sam A. Baker State Park: Nestled 12.9km from Southeast Missouri, this stunning state park offers breathtaking scenery and outdoor adventures. Enjoy hiking trails, picnic spots, and opportunities for wildlife viewing amidst the natural beauty of the area.
Walnut Hollow Lake: Located 20.9km away, Walnut Hollow Lake is perfect for a romantic day out. With its sandy beach and picturesque surroundings, it's an ideal spot for swimming, sunbathing, and enjoying peaceful moments by the water.
K Bridge Recreation Area: Situated 27.4km from Southeast Missouri, this urban park is family-friendly, featuring open spaces for picnics, play areas for children, and walking trails, making it a great place for a city escape with loved ones.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	34.9°F (1.6°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low
February	38.1°F (3.4000000000000004°C)	Light Rain	Mostly Sunny	Slightly Low	Average
March	48.0°F (8.9°C)	Light Rain	Mostly Sunny	Average	Average
April	57.6°F (14.2°C)	Light Rain	Mostly Sunny	Average	Slightly High
May	67.3°F (19.6°C)	Light Rain	Mostly Sunny	Average	Average
June	76.5°F (24.700000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
July	79.2°F (26.200000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Average
August	77.2°F (25.1°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
September	71.6°F (22.0°C)	Light Rain	Mostly Sunny	Average	Average
October	59.9°F (15.5°C)	Light Rain	Mostly Sunny	Average	Average
November	47.5°F (8.6°C)	Light Rain	Mostly Sunny	Average	Slightly Low
December	39.4°F (4.1000000000000005°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low

The nearest major airports for your trip to Southeast Missouri

For your visit to Southeast Missouri, you can fly into several major airports. St. Louis Lambert International Airport (STL) is situated 154.5km away and features nearby hotels such as The Ritz-Carlton (11.3km), the Royal Sonesta Chase Park Plaza (14.5km), and Ameristar Casino Resort and Spa (11.3km). Fort Leonard Wood Regional Airport (TBN) is also 154.5km distant, with options like Z Loft Extended Stay Hotel, Quality Inn St. Robert, and Holiday Inn Express, all within 9.7km. Additionally, Paducah Barkley Regional Airport (PAH) is 152.9km away, offering hotels like The Respite Bed and Breakfast (14.5km) and Drury Inn (8.0km).

Southeast Missouri Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southeast Missouri

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Star rating

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Our top choices for Southeast Missouri hotels

1. Shepherd Mountain Inn

2. Madison Inn Lodge

3. Hampton Inn & Suites By Hilton Festus

4. Holiday Inn Express & Suites Perryville by IHG

5. Crown Pointe Lodge, BW Signature Collection

6. Fairfield Inn & Suites by Marriott Poplar Bluff

7. Super 8 by Wyndham Farmington

8. Drury Inn & Suites Poplar Bluff

9. EC Reed's Mercantile and Hotel

10. Baymont Inn and Suites by Wyndham Farmington, MO

11. Hampton Inn Poplar Bluff

12. Fairfield Inn & Suites by Marriott Cape Girardeau

13. Fort Davidson Hotel

14. Holiday Inn Express & Suites Farmington by IHG

15. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

16. The Riverview

17. Super 8 by Wyndham Perryville

18. Drury Inn & Suites Jackson MO

19. Drury Plaza Hotel Cape Girardeau Conference Center

20. Honeysuckle Inn - Mountain View

Vacation Rentals in Southeast Missouri

Sam A Baker State Park

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Urban Lofts

The Atrium - A Boutique Hotel

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

Tiny Houses of French Village

Lake Wappapello

Walk to Dtwn: Ironton Home in Historic District

Walk to Current River: Ozarks Adventure Home!

Cozy Belgrade Cottage w/ Wood-burning Stove!

Cottage w/ Yard, Walk to Historic Attractions

Stay near popular Southeast Missouri attractions

Elephant Rocks State Park

Southeast Missouri State University

Lake Wappapello

Century Casino & Hotel Cape Girardeau

Century Casino Caruthersville

Learn more about Southeast Missouri

Top Southeast Missouri Hotel Reviews

Hampton Inn Poplar Bluff

The Riverview

Crown Pointe Lodge, BW Signature Collection

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Super 8 by Wyndham Sikeston/Miner Area

Drury Inn & Suites Hayti Caruthersville

Candlewood Suites Cape Girardeau by IHG

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Days Inn and Suites by Wyndham Sikeston

Pear Tree Inn Cape Girardeau West

Comfort Inn Festus - St Louis South

Motel 6 Poplar Bluff, MO

Hampton Inn Poplar Bluff

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

Find great hotels near Southeast Missouri

Where to stay near Southeast Missouri

Things to do near Southeast Missouri

Booking tips and Expedia advantages for Southeast Missouri

Find the best attractions near Southeast Missouri

Best time to go to Southeast Missouri

The nearest major airports for your trip to Southeast Missouri

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