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Luxury Hotels in Sikeston, Missouri

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Check availability on Sikeston Luxury Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 10 - Oct 12
Next weekend
Oct 17 - Oct 19

Top Sikeston Luxury Hotels

Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout drapes

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"Staff were great."
The price is P3,640
P4,149 total
includes taxes & fees
Nov 2 - Nov 3
Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1004)
"Room was clean, it is an affordable option to stay for a day or two "
The price is P4,050
P4,569 total
includes taxes & fees
Oct 7 - Oct 8
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.2 out of 10, Good, (648)
"nice stay"
The price is P3,148
P3,552 total
includes taxes & fees
Oct 7 - Oct 8
Quality Inn
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Very nice and quiet "
The price is P5,208
P5,987 total
includes taxes & fees
Oct 19 - Oct 20
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Excellent place. Really friendly staff"
The price is P5,208
P5,874 total
includes taxes & fees
Oct 12 - Oct 13
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Convenient to St Francis Medical Center. It is quiet, staff is friendly and tge breakfast a plus "
Mary 4-night trip
Posted 4 days ago
Pear Tree Inn Cape Girardeau Near the Medical Center
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Spacious room "
Barbara 1-night trip
Posted 3 weeks ago
Days Inn and Suites by Wyndham Sikeston

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Are you looking for a luxury hotel for your stay in Sikeston?
Use Expedia and let us help you arrange a flight to Cairo, IL (CIR-Cairo Regional) airport or Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Sikeston has to offer. During your visit, you might want to enjoy the shopping which Sikeston is known for.
When can I expect good weather in Sikeston?
Planning for the weather is a good way to make your trip to Sikeston relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do in Sikeston?
Experience all that Sikeston has to offer when you visit Sikeston Depot Museum, Central Park, and Front Street Studio & Art Gallery. If you have a little extra time during your trip, you might want to make a stop at Stoddard County Civil War Memorial Cemetery and Hunter-Dawson State Historic Site.