Serra Mesa Hotels near San Diego

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 3 - Aug 4
Tomorrow
Aug 4 - Aug 5
Next weekend
Aug 8 - Aug 10
In two weeks
Aug 15 - Aug 17

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Serra Mesa, San Diego

Best Western San Diego Pacific Beach/Mission Bay
Relax by the pool surrounded by palm trees and a building in the background.

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1256)
"Excellent hotel !! "
The price is P5,444
P6,258 total
includes taxes & fees
Aug 4 - Aug 5
Best Western San Diego Pacific Beach/Mission Bay
Sycuan Casino Resort
Relax by the resort pool surrounded by palm trees and a pebble bed.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1453)
"We had a wonderful stay, will definitely visit again!"
Sycuan Casino Resort
Best Western Premier Hotel Del Mar
Stands proudly amidst a manicured lawn and parking area, this charming two-story building boasts a traditional architectural style with a prominent chimney and tiled roof.

Best Western Premier Hotel Del Mar

3.0 star property
9.2 out of 10, Wonderful, (1004)
"Cute, quaint hotel with an ocean view."
The price is P7,366
P8,338 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Premier Hotel Del Mar
Gaslamp Plaza Suites
Experience the grandeur of our lobby, featuring a stunning chandelier, elegant marble floor, and a beautifully designed reception desk.

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1005)
"I love their clean bathrooms and been able to choose a suite over a standard room also been "
The price is P6,340
P7,212 total
includes taxes & fees
Aug 7 - Aug 8
Gaslamp Plaza Suites
Sea Harbor Hotel
Boats docked in a serene marina, offering a tranquil waterfront experience.

Sea Harbor Hotel

2.0 star property
8.6 out of 10, Excellent, (911)
"Great location, very customer friendly staff."
The price is P12,654
P14,267 total
includes taxes & fees
Aug 8 - Aug 9
Sea Harbor Hotel
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Grand Central Hotel features a symmetrical facade with evenly spaced windows and a grand arched entrance.

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

4.0 star property
9.2 out of 10, Wonderful, (443)
"Unique place to stay, great taste, excellent location!!! "
The price is P8,085
P9,358 total
includes taxes & fees
Sep 1 - Sep 2
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
The Rambler Motel
Relax by the pool surrounded by lounge chairs and umbrellas.

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1877)
"Very pleased with this stay."
The price is P6,340
P7,335 total
includes taxes & fees
Aug 4 - Aug 5
The Rambler Motel
Berkshire Motor Hotel
Enjoy cooking in this well-equipped kitchen with appliances and a dining area.

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (953)
"Great location within walking distance from the places we wanted to visit."
The price is P5,753
P6,486 total
includes taxes & fees
Aug 11 - Aug 12
Berkshire Motor Hotel
Valli Hi Motel
Relax in a spacious room with a large bed, wooden desk, and comfortable seating area.

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1012)
"Great hotel "
Valli Hi Motel
The Encinitan Hotel & Suites
Relax by the pool surrounded by lush tropical plants and palm trees, with lounge chairs and umbrellas providing shade.

The Encinitan Hotel & Suites

3.0 star property
8.0 out of 10, Very Good, (1078)
"Great location / family friendly "
The Encinitan Hotel & Suites
Paradise Point Resort & Spa
Guests can enjoy waterfront views and access to a dock area with sailboats.

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2201)
"We really enjoyed our stay"
The price is P8,442
P12,648 total
includes taxes & fees
Aug 24 - Aug 25
Paradise Point Resort & Spa
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Two single beds with geometric-patterned bedding and a dark headboard, set against a backdrop of white and blue walls.

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1173)
"Nice hotel to stay in "
The price is P4,827
P5,500 total
includes taxes & fees
Aug 11 - Aug 12
Studio 6 Suites San Ysidro, CA -San Diego South Bay
The Atwood Hotel San Diego - SeaWorld/Zoo
Relax by the pool surrounded by lounge chairs and palm trees.

The Atwood Hotel San Diego - SeaWorld/Zoo

3.0 star property
7.8 out of 10, Good, (1826)
"Clean, good location, easy freeway access."
The Atwood Hotel San Diego - SeaWorld/Zoo
Kings Inn San Diego
Relax in the hotel's central seating area, surrounded by a staircase and reception desk.

Kings Inn San Diego

2.5 star property
8.8 out of 10, Excellent, (3340)
"Excellent stay as always!"
Kings Inn San Diego
Hotel Palmeras Chula Vista
Guests can park adjacent to the building, with a covered entrance nearby.

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1799)
"Nice spot short drive from DT San diego"
The price is P5,544
P6,099 total
includes taxes & fees
Aug 4 - Aug 5
Hotel Palmeras Chula Vista
Handlery Hotel
Relax by the resort's large pool surrounded by lounge chairs and umbrellas, set amidst lush palm trees and tropical plants.

Handlery Hotel

3.5 star property
8.2 out of 10, Very Good, (1915)
"Great place for a quick stay, really enjoyed to facility"
Handlery Hotel
Pleasant Inn
Two beds with white and red bedding, a desk, chair, TV, and window with curtains.

Pleasant Inn

2.5 star property
8.4 out of 10, Very Good, (1092)
"We really enjoyed our visit 😊"
The price is P5,317
P6,102 total
includes taxes & fees
Aug 25 - Aug 26
Pleasant Inn
Howard Johnson by Wyndham National City/San Diego South
Contemporary bathroom with sleek countertop, white sink, and large mirror.

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1003)
"Great place 👍"
The price is P4,400
P4,849 total
includes taxes & fees
Aug 10 - Aug 11
Howard Johnson by Wyndham National City/San Diego South
Urban Boutique Hotel
Check-in with ease at our reception area, featuring online booking services and a comfortable seating area.

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1224)
"Cozy and very close to train station and to public transportation."
Urban Boutique Hotel
Best Western Plus Marina Gateway Hotel
Two large beds with blue and white bedding, a desk, and a potted plant adorn this stylish room.

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3173)
"This location was great for our family get away"
The price is P8,324
P9,172 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Plus Marina Gateway Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Belmont Park which includes a garden and rides
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach Park showing a sandy beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter which includes signage, a bar and night scenes
Gaslamp Quarter map

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Harlem of the West Sites is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"The staff is very friendly and helpful. We had a small issue with the AC in our room and they handled it right away and resolved the issue quickly. The rest of the weekend was great with our stay!"
Timothy 2-night trip
Posted 9 hours ago
Bay Club Hotel & Marina

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.