Serra Mesa Hotels near San Diego

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Our top choices for Serra Mesa hotels

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1271)
"Locations is excellent and the front desk lady was friendly "
Canada
Ju
Urban Boutique Hotel

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1014)
"Yes everything was great I will stay there again."
United States
Sergio
The price is P6,929
P7,882 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Gaslamp Plaza Suites

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very Good, (1869)
"Courteous staff and clean room. "
United States
Rachel
The price is P5,185
P5,960 total
includes taxes & fees
Dec 23 - Dec 24
GreenTree Inn San Diego Mission Bay

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1912)
"Great check-in experience, convenient parking, the room was clean and bed was comfortable. The city view option was exceptionally pleasant. Will stay again! "
United States
Mike
La Pensione Hotel

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1165)
"Clean room, great location "
United States
Benjamin
The price is P3,918
P4,503 total
includes taxes & fees
Dec 25 - Dec 26
Heritage Inn San Diego

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
9.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1002)
"Great staff and location."
United States
Lisa
The price is P7,464
P8,640 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Plus Bayside Inn

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very Good, (1416)
"our stay was great and staff was supportive..."
United States
Ramesh
The price is P4,650
P5,252 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SureStay Hotel by Best Western San Diego Pacific Beach

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4116)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is P5,226
P6,008 total
includes taxes & fees
Dec 22 - Dec 23
Wyndham Garden San Diego Near SeaWorld

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
9.6 km from Serra Mesa
8.2 out of 10, Very Good, (2287)
"The room was great, the bed was comfortable."
United States
PAM
The price is P6,140
P7,119 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn San Diego-Downtown

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3146)
"good hotel "
United States
Lala
The price is P4,992
P5,738 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Comfort Inn Sea World Area

The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
8.8 out of 10, Excellent, (557)
"beautiful hotel, well maintained facilities, convenient location, very kind staff"
United States
Sergio
The price is P7,000
P7,962 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Beau Downtown San Diego Gaslamp Quar

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Marina District, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (2700)
"Great place if you want to stay near glaslamp quarter district."
Mexico
Daniel
The Horton Grand, Downtown/Gaslamp Quarter

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.4 out of 10, Very Good, (1656)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1066)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is P7,939
P10,908 total
includes taxes & fees
Dec 25 - Dec 26
The Westin San Diego Bayview

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
12.2 km from Serra Mesa
8.6 out of 10, Excellent, (1005)
"Great stay"
United States
Naomi
Sea Harbor Hotel

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
11.9 km from Serra Mesa
7.8 out of 10, Good, (1187)
"Great location on the bay and close to the airport "
United States
Shawn
The price is P4,993
P5,640 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Comfort Inn San Diego Airport At The Harbor

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1454)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 7.4 km from Serra Mesa
8.0 out of 10, Very Good, (1431)
"Great place We will stay here again. "
United States
Derek
The price is P5,323
P6,120 total
includes taxes & fees
Jan 7 - Jan 8, 2026
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
11.8 km from Serra Mesa
8.6 out of 10, Excellent, (1634)
"The breakfast options were good and the staff were very helpful."
Canada
Gail or Rob
The price is P5,867
P6,733 total
includes taxes & fees
Dec 21 - Dec 22
Best Western Yacht Harbor Hotel

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1230)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is P8,050
P9,333 total
includes taxes & fees
Dec 21 - Dec 22
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Find out more about Serra Mesa

Top reasons to visit Serra Mesa

  • Family-Friendly Activities: Serra Mesa is ideal for family outings, offering numerous attractions suitable for all ages.
  • Outdoor Adventures: Enjoy a blend of urban parks and private gardens for leisurely strolls and outdoor fun.
  • Cultural Experiences: Explore local colleges and universities, immersing yourself in the area's rich history.
  • Shopping Options: Discover a variety of local centres and malls for a delightful shopping experience.
  • Diverse Accommodation: Choose from family-friendly and pet-friendly lodgings tailored to meet diverse traveller needs.

Find great hotels near Serra Mesa

Explore the charming Serra Mesa area of San Diego, where a variety of accommodation options await to suit every traveller's needs. From family-friendly hotels to pet-friendly lodgings, there's something for everyone seeking adventure and relaxation. Discover the best hotels, including those in nearby Kearny Mesa, and read reviews to find the perfect place for your holiday. Enjoy a memorable stay in this delightful neighbourhood that promises a unique Californian experience.

  • Days Inn by Wyndham San Diego Hotel Circle: This charming 3-star hotel is a haven for adventure seekers and business travellers alike, located merely 4.8km from Serra Mesa. The hotel prides itself on its LGBTQIA-friendly atmosphere, making it an inclusive space for all. Guests can indulge in a variety of adventure sports, with options like surfing, parasailing, and windsurfing available nearby, ensuring an exhilarating stay. The property also provides essential amenities for business travellers, making it a versatile choice for those looking to mix work and play.
  • Best Western Seven Seas: Another splendid 3-star option, Best Western Seven Seas is just 4.8km from Serra Mesa and caters perfectly to families and business travellers. This hotel offers a range of on-site and nearby adventure activities, including windsurfing, parasailing, and mountain biking, ensuring a fun-filled experience for guests of all ages. Families will appreciate the child-friendly amenities, such as complimentary cribs, which make it an ideal choice for those travelling with little ones. The welcoming atmosphere combined with recreational options makes it a family favourite.
  • California Suites Hotel: A practical lodging choice, California Suites Hotel is located 4.8km from Serra Mesa and is tailored for business travellers seeking comfort and convenience. While it may not boast a plethora of amenities, it provides essential services that cater to the needs of professionals. The hotel's tranquil atmosphere allows guests to focus on their work commitments while still being close to the vibrant attractions of San Diego. Whether you’re in town for a conference or business meeting, this hotel offers a solid base for your stay.

Where to stay near Serra Mesa

Serra Mesa, a charming neighbourhood in San Diego, offers a delightful blend of family-friendly activities and outdoor adventures. Its convenient location allows easy exploration of nearby areas like Mira Mesa, where friendly locals and rich history await. Whether you seek budget-friendly excursions or a vibrant city atmosphere, Serra Mesa serves as the perfect base for a memorable Californian holiday.

  • San Diego: As a vibrant coastal city, San Diego serves as the heart of the region, with Serra Mesa nestled within its boundaries. Renowned for its year-round pleasant climate, visitors flock here for family-oriented activities, outdoor adventures, and beautiful beaches. The city boasts a variety of attractions, including world-class theme parks and picturesque coastal areas. Shopping enthusiasts will enjoy the numerous shopping centres and malls that offer a range of local and international brands. With a mix of cultural experiences and recreational options, San Diego truly caters to every traveller's taste.
  • Kearny Mesa: Just 3.2km from Serra Mesa, Kearny Mesa is a lively neighbourhood that draws visitors with its family-friendly atmosphere and city-themed experiences. The area is known for its diverse dining options, shopping centres, and educational venues, making it an excellent spot for those looking to immerse themselves in local culture. Kearny Mesa is also home to several attractions, including popular theme parks and vibrant tourist precincts. With its convenient location and array of activities, Kearny Mesa offers a delightful experience for all.
  • Linda Vista: Located a mere 3.2km from Serra Mesa, Linda Vista is a charming neighbourhood that attracts families and outdoor enthusiasts alike. Visitors can enjoy a variety of activities, including access to educational facilities and shopping centres. The local highlights include a nearby theme park and the scenic bay, perfect for leisurely walks and relaxation. With its welcoming community and array of recreational opportunities, Linda Vista promises a rewarding experience for those seeking a blend of relaxation and adventure.

Things to do near Serra Mesa

Serra Mesa, San Diego, offers a delightful blend of family-friendly activities, outdoor adventures, and urban experiences. Visitors can enjoy a variety of educational attractions, as well as shopping at local centres and malls. For those seeking a leisurely afternoon escape, shopping options abound, while the nightlife provides an exciting atmosphere to unwind and explore after a day of activities.

Shopping

In Serra Mesa, you can enjoy shopping at the nearby Little Saigon, offering a vibrant mix of cultural goods, just 6.4km away. For a more extensive experience, visit the Fashion Valley Mall, 4.8km away, or Westfield UTC, 9.7km away, both offering diverse shopping and entertainment options.

Recreation

Petco Park offers an exhilarating atmosphere for sports enthusiasts, located 11.3km from Serra Mesa. The Rady Shell at Jacobs Park provides captivating musical performances, also 11.3km away, perfect for entertainment lovers. Morley Field Sports Complex, 6.4km away, is ideal for relaxation and wellness activities amidst nature.

Adventure

At Barnes Tennis Center, located 11.3km from Serra Mesa, immerse yourself in a vibrant tennis atmosphere with excellent facilities. The Aztec Tennis Center, 6.4km away, offers thrilling matches and a lively community. Similarly, the Urban Village Tennis Center, also 6.4km distant, provides a dynamic setting for tennis enthusiasts.

Nightlife

Experience the enchanting atmosphere at the Old Globe Theater, where culture and romance intertwine. For a family-friendly outing, enjoy the whimsical Balboa Park Carousel. For a dose of adventure, visit Boomers San Diego, an exciting arcade adventure zone perfect for families.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Serra Mesa

For a budget-friendly visit to Serra Mesa, San Diego, consider travelling between November and January when accommodation prices are lower. Tuesdays tend to be the cheapest days to stay, while Saturdays are the priciest. Use Expedia's search tool to filter options by budget and amenities, and consider eco-certified hotels for sustainable choices. Booking a package that combines flights and hotel stays can also save you money. Look out for minute deals and free night offers to maximise your savings during your trip.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Serra Mesa are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Serra Mesa is Tuesday. The most expensive day to stay around Serra Mesa is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To find the most affordable prices and offers, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You may find it beneficial to save money by booking an Expedia package, which allows you to combine your hotel stay in Serra Mesa with your flights and activities.

Find the best attractions near Serra Mesa

Serra Mesa is ideal for family-oriented and outdoor getaways, offering a blend of urban charm and natural beauty. Visitors can explore a variety of attractions, including modern colleges and universities, urban parks, and private gardens. The area's points of interest cater to travellers seeking cultural experiences, family fun, and outdoor adventures, ensuring a delightful holiday for all.

  • Mission Bay: Located 8.0km from Serra Mesa, Mission Bay is a stunning waterfront area perfect for outdoor activities. Enjoy sandy beaches, scenic views, and a variety of water sports, making it an ideal spot for relaxation and adventure alike.
  • Hotel Circle: Situated 4.8km away, Hotel Circle is a vibrant street lined with numerous hotels, restaurants, and shops. This area captures the essence of city life, offering a bustling atmosphere and convenient access to various attractions.
  • Balboa Park: Also 8.0km from Serra Mesa, Balboa Park is a picturesque private garden showcasing beautiful landscapes and rich cultural institutions. Explore its museums, gardens, and walking paths for a tranquil escape in the heart of San Diego.

Best time to go to Serra Mesa

The best time to visit Serra Mesa is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. February is its coolest month on average. At this time, visitor numbers are average and weather is sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.4°F (14.1°C)Light RainSunnyModerately LowSlightly Low
February56.8°F (13.8°C)Light RainSunnyAverageAverage
March58.1°F (14.5°C)No RainMostly SunnyModerately HighAverage
April60.6°F (15.9°C)No RainSunnyAverageAverage
May62.6°F (17.0°C)No RainSunnyAverageAverage
June66.4°F (19.1°C)No RainSunnyModerately HighSlightly High
July70.5°F (21.4°C)No RainSunnyModerately HighSlightly High
August72.3°F (22.4°C)No RainSunnyAverageSlightly High
September72.0°F (22.2°C)No RainSunnyAverageAverage
October68.2°F (20.1°C)No RainSunnyModerately LowAverage
November62.6°F (17.0°C)No RainSunnyModerately LowSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Serra Mesa

Visiting Serra Mesa, San Diego, is convenient with several major airports nearby. San Diego International Airport (SAN) is located 9.7km away, with luxurious hotels such as the 5-star Pendry San Diego and The US Grant, both about 3 and 3.2km from the airport respectively. Tijuana International Airport (TIJ) is 32.2km away, offering options like the 4.5-star Quartz Hotel & SPA and Real Inn Tijuana, both just 4.8km from the airport. Montgomery Field (MYF) is the closest at 0.9.7km, with notable hotels including the 5-star Fairmont Grand Del Mar and the 4.5-star Westgate Hotel within 11.3km. Each hotel provides easy access to their respective airports.

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels will I be able to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.
What can I see and do in this San Diego neighborhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.