Santo Domingo Hotels near Mexico City

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santo Domingo hotels

Hotel Catedral

Hotel Catedral
4.0 star property
Historic Center, 12.4 km from Santo Domingo
9.4 out of 10, Exceptional, (2,696 reviews)
"Great location, friendly staff. "
United States
Jennifer
Hotel Catedral

Hotel Juarez

Hotel Juarez
2.5 star property
Historic Center, 12.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1,821 reviews)
"Excelente hotel"
Mexico
César augusto
The price is P1,738
P2,077 total
includes taxes & fees
Jan 12 - Jan 13
Hotel Juarez

Hotel Punto MX

Hotel Punto MX
3.5 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,491 reviews)
"Very clean hotel and breakfast was great. "
Canada
Jesse
The price is P3,080
P3,680 total
includes taxes & fees
Jan 13 - Jan 14
Hotel Punto MX

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza, 14.5 km from Santo Domingo
8.8 out of 10, Excellent, (11,972 reviews)
"Nice location for stop over travels"
United Kingdom
Ulises Tirado
The price is P6,773
P8,093 total
includes taxes & fees
Jan 26 - Jan 27
Camino Real Aeropuerto Mexico

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City
4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.8 out of 10, Exceptional, (2,694 reviews)
"Great stay "
United States
CONI
The price is P9,640
P11,520 total
includes taxes & fees
Jan 28 - Jan 29
Zocalo Central & Rooftop Mexico City

We Hotel Aeropuerto

We Hotel Aeropuerto
3.5 star property
Venustiano Carranza, 14.1 km from Santo Domingo
8.4 out of 10, Very Good, (2,164 reviews)
"Our stay was great room clean the food was really good "
United States
Laura
The price is P5,189
P6,201 total
includes taxes & fees
Jan 18 - Jan 19
We Hotel Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto
3.5 star property
Venustiano Carranza, 14.3 km from Santo Domingo
8.8 out of 10, Excellent, (3,281 reviews)
"Great place, great staff "
United States
Jesus
The price is P7,407
P8,852 total
includes taxes & fees
Jan 16 - Jan 17
Fiesta Inn Ciudad de Mexico Aeropuerto

Barceló México Reforma

Barceló México Reforma
4.5 star property
11.9 km from Santo Domingo
9.4 out of 10, Exceptional, (5,162 reviews)
"Great hotel!"
United States
Alma
The price is P7,262
P8,678 total
includes taxes & fees
Feb 2 - Feb 3
Barceló México Reforma

Hotel Bellas Artes

Hotel Bellas Artes
4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.6 out of 10, Exceptional, (639 reviews)
"Great stay"
United States
Ignacio Guzman
The price is P4,557
P5,445 total
includes taxes & fees
Feb 2 - Feb 3
Hotel Bellas Artes

Hotel Embassy

Hotel Embassy
3.0 star property
Roma Norte, 10.5 km from Santo Domingo
8.6 out of 10, Excellent, (3,270 reviews)
"Clean, comfy, nice staff and great location. "
United States
Shay
The price is P2,373
P2,836 total
includes taxes & fees
Jan 12 - Jan 13
Hotel Embassy

Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico
3.0 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,112 reviews)
"Always a great place to stay while in CDMX "
United States
Juan
The price is P4,811
P5,749 total
includes taxes & fees
Jan 28 - Jan 29
Hampton Inn & Suites Mexico City - Centro Historico

Historico Central Hotel

Historico Central Hotel
4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2,409 reviews)
"Excellent service - beautiful decor- great location!"
United States
Debra
The price is P9,344
P11,166 total
includes taxes & fees
Jan 26 - Jan 27
Historico Central Hotel

Hotel PF

Hotel PF
3.5 star property
Zona Rosa, 10.6 km from Santo Domingo
9.0 out of 10, Wonderful, (2,320 reviews)
"Ideally located comfortable and clean hotel for a reasonable cost. "
United States
Toni
The price is P4,479
P5,352 total
includes taxes & fees
Feb 9 - Feb 10
Hotel PF

Galeria Plaza Reforma

Galeria Plaza Reforma
4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.4 out of 10, Exceptional, (3,258 reviews)
"Excellent stay "
United States
Arturo
The price is P7,759
P9,272 total
includes taxes & fees
Jan 12 - Jan 13
Galeria Plaza Reforma

Eurostars Zona Rosa Suites

Eurostars Zona Rosa Suites
4.0 star property
Zona Rosa, 10.8 km from Santo Domingo
8.8 out of 10, Excellent, (1,008 reviews)
"Yes, the housekeeping and the front desk were great "
United States
Alfonso
The price is P3,347
P4,000 total
includes taxes & fees
Feb 9 - Feb 10
Eurostars Zona Rosa Suites

Courtyard Mexico City Airport

Courtyard Mexico City Airport
4.0 star property
Venustiano Carranza, 14.8 km from Santo Domingo
9.4 out of 10, Exceptional, (1,797 reviews)
"Great staff, quiet, great shuttle, amazing food"
United States
Brett
The price is P9,813
P11,727 total
includes taxes & fees
Jan 24 - Jan 25
Courtyard Mexico City Airport

NH Collection Mexico City Airport T2

NH Collection Mexico City Airport T2
4.0 star property
Venustiano Carranza, 13.8 km from Santo Domingo
8.6 out of 10, Excellent, (3,623 reviews)
"Excelente hotel"
Mexico
Rosario
The price is P10,374
P12,397 total
includes taxes & fees
Jan 18 - Jan 19
NH Collection Mexico City Airport T2

Fiesta Americana Reforma

Fiesta Americana Reforma
4.0 star property
Juárez, 11.6 km from Santo Domingo
9.2 out of 10, Wonderful, (4,201 reviews)
"It was very good place to stay "
United States
Ubaldo
The price is P6,803
P8,129 total
includes taxes & fees
Feb 6 - Feb 7
Fiesta Americana Reforma

Geneve Ciudad de México

Geneve Ciudad de México
4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,765 reviews)
"Always a pleasant stay when we are here "
United States
James
The price is P6,560
P7,839 total
includes taxes & fees
Jan 12 - Jan 13
Geneve Ciudad de México

Holiday Inn Express Mexico Aeropuerto by IHG

Holiday Inn Express Mexico Aeropuerto by IHG
3.0 star property
10.6 km from Santo Domingo
9.2 out of 10, Wonderful, (1,610 reviews)
"The stay was excellent and the breakfast buffet was outstanding. I highly recommend this hotel all the staff members were very friendly! "
United States
Elvia
The price is P5,310
P6,346 total
includes taxes & fees
Feb 3 - Feb 4
Holiday Inn Express Mexico Aeropuerto by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like MUCA Roma and Centro Cultural El Punto, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

Historic Center

You might take some time to check out the interesting museums in Historic Center. Spend some time visiting top spots like Palacio de Bellas Artes, and catch the metro at Allende Station or Bellas Artes Station to see more of the area.

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

Frequently asked questions

What is Santo Domingo like?
Travelers to Mexico City's Santo Domingo neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels should I expect to find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodations in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals in Santo Domingo.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro, and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.

Explore a world of travel with Expedia