Santee Hotels

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Our top choices for Santee hotels

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (659)
Energizing Santee hotel with an indoor pool for morning swims and a 24-hour fitness center. Enjoy free breakfast, WiFi, and parking. Close to Santee Cooper Country Club and Santee National Golf Club. Guests rave about the helpful staff.

"Nice place to stay"
Canada
Tanya
The price is P6,294
P6,987 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Tru By Hilton Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1416)
This peaceful hotel offers complimentary breakfast, WiFi and parking near Santee National Golf Club. Guests consistently praise the quiet atmosphere, comfortable accommodations and helpful staff. The convenient location provides easy access to everything needed.

"Room was very nice and staff was very nice"
United States
Rupert
The price is P4,411
P4,896 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Baymont by Wyndham Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1000)
Set in a peaceful location, this hotel offers free breakfast, WiFi, and parking. Guests can enjoy the outdoor pool or workout at the health club. The helpful staff ensure comfort while Santee Cooper Country Club and Santee National Golf Club are just moments away.

"Staff very friendly, room super clean"
United States
Karine
The price is P7,118
P7,901 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Fairfield Inn & Suites by Marriott Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (980)
Adjacent to a golf course, this hotel offers an indoor pool and convenient on-site dining. Guests love the helpful staff and clean rooms. Nearby attractions include Santee Cooper Country Club and Santee National Golf Club, while free WiFi and parking enhance your stay.

"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is P7,003
P7,773 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Holiday Inn Santee by IHG

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1008)
Escape to a tranquil retreat in Santee's entertainment district where helpful staff welcome you. Enjoy the seasonal outdoor pool after exploring nearby Santee Cooper Country Club, then recharge with complimentary breakfast before your next adventure.

"It was quite and comfortable stay"
United States
Shankar
The price is P6,050
P6,716 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Comfort Inn & Suites Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1001)
"Great place to stop on a road trip! Breakfast was great, pets allowed, friendly staff. "
United States
Stephanie
The price is P7,936
P8,809 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn Santee-I-95

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1000)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is P6,950
P7,715 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Best Western Plus Santee Inn

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (683)
This Santee hotel offers daily continental breakfast and complimentary WiFi and parking. Praised for helpful staff and clean rooms, the location provides easy access to Santee Cooper Country Club and Santee National Golf Club.

"Nice quiet room and a delicious breakfast at a reasonable rate."
United States
Joseph B
The price is P3,590
P3,985 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Travelodge by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (459)
Immerse yourself in Southern hospitality at this Quality Inn where 7 restaurants and a seasonal outdoor pool await. Enjoy free breakfast, WiFi and parking while exploring nearby Santee Cooper Country Club. Guests consistently praise the helpful staff and clean accommodations.

"exellent service"
United States
Mirjana
The price is P3,200
P3,878 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Quality Inn & Suites Santee I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (640)
A perfect stopover with free breakfast, parking, and WiFi at this lakeside hotel. Just minutes from Santee Cooper Country Club and offering easy access to water skiing adventures. Modern rooms provide a restful retreat after exploring Santee National Golf Club.

"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is P4,117
P4,570 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Red Roof Inn Santee

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (441)
Tranquil accommodations next to Santee Cooper Country Club with a refreshing seasonal outdoor pool. Free perks include daily on-the-go breakfast, WiFi, and parking. Conveniently located near Santee National Golf Club for the perfect golf getaway.

"The staff was very friendly and helpful. Room was clean and beds were so comfortable. "
United States
Kathy
The price is P4,412
P4,897 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Santee

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (545)
This golf-adjacent hotel offers an outdoor pool with poolside bar, plus a 24-hour fitness center for active travelers. Rooms include refrigerators and microwaves. Santee Cooper Country Club is nearby, with free WiFi and parking for added convenience.

"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is P4,631
P5,140 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (310)
This budget-friendly hotel sits close to Santee Cooper Country Club and Santee National Golf Club. Guests appreciate the convenient amenities including complimentary WiFi, free parking, and 24-hour reception service.

"Last minute arrangements stay was quiet and peaceful "
United States
Iasia
The price is P3,722
P4,132 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Econo Lodge Santee

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
2.5 star property
Orangeburg
8.4 out of 10, Very Good, (704)
Situated near attractions like Smith-Hammond-Middleton Memorial Center, this hotel offers seasonal swimming and convenient workout options. Enjoy complimentary breakfast, WiFi, and parking while business travelers appreciate the friendly staff and clean accommodations.

"Overall a great place to stay!"
United States
Troy
The price is P4,941
P5,485 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Fairfield Inn by Marriott Orangeburg

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1014)
"Great stay"
United States
Thomas
The price is P6,222
P6,907 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Tru by Hilton Orangeburg

Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1000)
Wake up to a complimentary breakfast at this welcoming Orangeburg hotel with seasonal outdoor pool and fitness center. Free WiFi and parking add convenience while helpful staff ensure a pleasant stay near local attractions.

"Great place and pet friendly. Rooms are clean and comfortable."
United States
Penny
The price is P5,129
P5,694 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Spark by Hilton Orangeburg

Best Inn of Manning

Best Inn of Manning
2.5 star property
Manning
7.8 out of 10, Good, (10)
"Clean, comfortable, and efficient stay with friendly helpful staff and great value for your money."
United States
Loren
The price is P4,311
P4,786 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Inn of Manning

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1006)
This business-friendly hotel offers free WiFi and full breakfast daily. Clean rooms provide a relaxing atmosphere after exploring Manning. Previous guests highly praise the helpful staff and overall cleanliness.

"For the money, a great option..."
United States
James
The price is P5,235
P5,811 total
includes taxes & fees
Jan 21 - Jan 22, 2026
SureStay Hotel by Best Western Manning

Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very Good, (558)
Swim year-round at this Orangeburg hotel with fitness center and free breakfast, parking, and WiFi. The helpful staff and prime location near Smith-Hammond-Middleton Memorial Center create a convenient hub for travelers.

"Would recommend this hotel for out of town guest with no hesitation. "
United States
Yvette
The price is P5,600
P6,216 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Inn & Suites Orangeburg

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1000)
Located just a short drive from Charleston International Airport, this hotel offers clean accommodations with premium comfort. Relax at the bar after a workout in the 24-hour fitness center. Free breakfast, WiFi, and parking enhance your visit.

"Staff is always super friendly!"
United States
Kirk
The price is P7,039
P7,813 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hampton Inn Manning
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Find out more about Santee

Top reasons to visit Santee

  • Stunning Natural Landscapes: Explore scenic lakes, picturesque state parks, and charming islands, perfect for outdoor enthusiasts.
  • Recreational Activities: Enjoy fishing for striped bass, golfing at local courses, and various outdoor adventures.
  • Tranquil Getaways: Ideal for romantic escapes or family-friendly outings amidst serene surroundings.
  • Southern Hospitality: Experience the friendly atmosphere and unique vibe of nearby towns.
  • Diverse Accommodation Options: Choose from charming hotels and motels catering to various needs, including pet-friendly and LGBTQIA-friendly options.

Find great hotels in and around Santee

For visitors to Santee, South Carolina, a variety of accommodation options await, including charming hotels and motels. Whether you're seeking pet-friendly facilities, a welcoming environment for LGBTQIA travellers, or suitable arrangements for business trips, Santee has something for everyone. Discover the best hotels and comfortable suites to enhance your stay, making your holiday memorable in this lovely destination.

  • Baymont by Wyndham Santee: This welcoming hotel offers a charming escape for both business and leisure travellers. Baymont by Wyndham Santee is particularly suited for pet lovers, allowing dogs and cats with a flexible pet policy. Guests appreciate the comfortable rooms, equipped with modern amenities, and the friendly atmosphere that makes it feel like a home away from home. Its strategic location in Santee provides easy access to local attractions, ensuring a convenient stay for all visitors. The hotel’s commitment to service and accommodating environment makes it a popular choice for those seeking a pet-friendly vacation experience.
  • Fairfield Inn by Marriott Orangeburg: Located 30.6km from Santee, Fairfield Inn by Marriott Orangeburg embodies a contemporary and professional atmosphere, ideal for business travellers. This hotel proudly welcomes the LGBTQIA community, providing an inclusive and supportive environment for all guests. The property is equipped with modern amenities and offers a complimentary breakfast to start your day on the right note. Its close proximity to local businesses and attractions makes it a convenient base for both work and leisure, ensuring that every visitor feels valued and comfortable during their stay.
  • Comfort Inn & Suites Santee: Perfectly designed for families, Comfort Inn & Suites Santee offers a warm and inviting environment for guests of all ages. The hotel features family-friendly amenities, including complimentary cribs for infants, making it an excellent choice for those travelling with children. Guests enjoy spacious rooms, a refreshing outdoor pool, and a complimentary breakfast to fuel your adventures. Located in Santee, this hotel provides easy access to local attractions, ensuring that families can create lasting memories together while enjoying a comfortable and stress-free stay.

Where to stay near Santee

Santee, South Carolina, offers a delightful blend of outdoor adventures and serene charm for travellers. Experience the friendly atmosphere as you explore picturesque landscapes and enjoy value golf at local courses. With its tranquil waters, Santee is perfect for romantic getaways or family-friendly excursions. Venture into nearby towns to soak up the Southern hospitality and uncover the region's unique vibe, making your vacation both memorable and enriching.

  • Vance: Nestled a mere 8.0km from Santee, Vance offers a delightful escape for those seeking outdoor adventures and captivating scenery. This charming city experiences a seasonal influx of visitors, particularly during the vibrant months of March to April and July. Explorers flock here for romantic experiences, with popular activities including golf and leisurely strolls in the local recreational areas. Nature enthusiasts will appreciate the nearby lake, national state park, and beach, providing ample opportunities for relaxation and exploration amidst stunning landscapes.
  • Summerton: Located 17.7km from Santee, Summerton is a hidden gem that promises a consistent travel experience throughout the year. Visitors are drawn to its picturesque surroundings and outdoor activities, with peak tourism occurring from March to April and July. The city is perfect for those seeking romance and adventure, featuring recreational areas and golf courses. Nearby attractions such as serene lakes, captivating water features, and quaint islands enhance the charm of Summerton, making it an ideal spot for leisurely exploration and creating lasting memories.
  • Elloree: Just 9.7km from Santee, Elloree beckons visitors with its enchanting landscapes and outdoor pursuits. This city enjoys a steady flow of tourists, particularly from March, July, and September. Visitors are lured by its romantic ambiance and opportunities for golf and recreation. The proximity to stunning natural attractions, including a picturesque lake and national park, makes Elloree a delightful destination for those seeking both tranquillity and adventure. Whether you’re exploring the lush surroundings or enjoying a round of golf, Elloree offers a perfect blend of relaxation and excitement.

Things to do in and around Santee

Santee, South Carolina, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can indulge in various activities such as exploring scenic recreational areas, enjoying a round of golf, or embarking on a day trip to savour the local scenery. Additionally, Santee offers opportunities for striped bass fishing and has nightlife options to enhance your holiday experience.

Shopping

Santee offers a delightful shopping experience. For unique gifts, visit Bee City, located 48.3km away. If you're up for a drive, Pocalla Crossing Shopping Center, 43.5km from Santee, provides a mix of family-friendly shops and local businesses, perfect for souvenirs and mementoes.

Recreation

Enjoy a round of golf at Santee Cooper Country Club, where outdoor vibes enhance your game. For a serene escape, explore the Santee National Wildlife Refuge, just 6.4km away, offering relaxation amidst nature. Alternatively, visit Patriots Sports Plex, 49.9km from Santee, for various wellness activities.

Adventure

Explore Lake Marion for fishing, boating, and kayaking amidst picturesque scenery. For a thrilling experience, try the Santee State Park trails for hiking and biking, where you can admire the stunning landscapes and local wildlife.

Nightlife

Santee offers a charming nightlife with options like the lively Santee Cooper Resort, perfect for enjoying a drink by the water. For a more laid-back evening, visit the local pubs where friendly locals share stories over craft beers and Southern cuisine, creating a warm and inviting atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santee

Santee, South Carolina, provides numerous ways to save while enjoying your visit. Many attractions, such as Taw Caw Creek, are free to enter. For transport, consider renting a bike or using the bus, as car rentals can be pricey. The best time to visit for savings is from December to February, avoiding peak seasons in April, May, and October. Booking on a Monday often yields lower prices, while Saturday is the priciest. Use Expedia to compare rates and secure deals by bundling your accommodation with flights and activities for added savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search wizard to tailor your preferences, including your budget, desired location, and type of accommodation. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels currently available. To discover the most affordable options and special offers, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santee with your flights and activities through an Expedia package.

Find the best attractions in and around Santee

Santee, South Carolina, is perfect for outdoor enthusiasts seeking scenic and romantic getaways. Visitors can explore stunning lakes, picturesque state parks, and charming islands. Key attractions include Santee State Park, which offers a wealth of activities for those wanting to immerse themselves in nature and enjoy beach-like experiences. This tranquil destination promises an unforgettable adventure for travellers looking to bask in the beauty of the great outdoors.

  • Santee Indian Mound and Fort Watson Site: This historical site, located 6.4km from Santee, offers a glimpse into the rich cultural heritage of the region. The ancient Indian mound provides fascinating insights into Native American history, while the nearby Fort Watson Site showcases remnants from the American Revolutionary War, making it a unique blend of natural and historical significance.
  • Santee State Park: Nestled within Santee, this national park is a haven for outdoor enthusiasts. With its stunning scenery, abundant wildlife, and diverse recreational activities, visitors can enjoy hiking, fishing, and camping, all surrounded by the beauty of nature.
  • Santee Town Hall: Situated in the heart of Santee, this town hall represents the local governance and community spirit. While it may not be a typical tourist attraction, its architecture and the vibrant atmosphere reflect the town's charm and character.

Best time to go to Santee

The best time to visit Santee can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santee falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Santee falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighAverage
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighSlightly High
May72.0°F (22.2°C)Light RainMostly SunnyAverageSlightly High
June78.6°F (25.9°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighAverage
August79.9°F (26.6°C)Light RainMostly SunnyAverageAverage
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowSlightly High
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Santee

Accessing Santee, South Carolina, is convenient via two major airports. Charleston International Airport (CHS) is located 78.9km away, with excellent hotel options such as The Charleston Place, The Dewberry Charleston, and Wentworth Mansion, all situated 14.5km from the airport and offering transfers and shuttles. Columbia Metropolitan Airport (CAE) is also 78.9km from Santee, with notable hotels like Graduate by Hilton Columbia SC, Doubletree by Hilton Columbia, and Marriott Columbia, all within 11.3km of the airport and easily accessible. Both airports provide a range of transportation services to facilitate your travel.

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals in Santee?
Wyndham Vacation Resorts Lake Marion: Visitors give good reviews to this Santee vacation home rental, which is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher, and a stovetop. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Tru By Hilton Santee is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Other good choices for you and your pet's trip include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites Santee I-95 is another choice with an onsite pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 126 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee State Park, and Lake Marion. A couple of additional sights to add to your agenda are Santee National Golf Club and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.

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