Santa Ana Hotels near Antigua Guatemala

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Mar 2 - Mar 3
Tomorrow
Mar 3 - Mar 4
This weekend
Mar 6 - Mar 8
Next weekend
Mar 13 - Mar 15

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Ana hotels

Garden view

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (23 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is P2,745
P3,349 total
includes taxes & fees
Mar 16 - Mar 17
Hostal Casa Buho
Front of property

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is P2,618
P3,194 total
includes taxes & fees
Mar 5 - Mar 6
Casa Buho B&B
Front of property

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (13 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo
Restaurant

Villa Sicilia

Villa Sicilia
2.0 star property
24 km from Santa Ana
8.0 out of 10, Very Good, (99 reviews)
"Everything was as advertised and good location "
United States
Jimmy
The price is P1,665
P2,032 total
includes taxes & fees
Mar 3 - Mar 4
Villa Sicilia
Interior

Hotel Don Felipe Airport

Hotel Don Felipe Airport
2.0 star property
20.8 km from Santa Ana
8.4 out of 10, Very Good, (33 reviews)
"Execelente "
Mexico
Mauricio Alberto
The price is P1,903
P2,322 total
includes taxes & fees
Mar 3 - Mar 4
Hotel Don Felipe Airport
Restaurant

Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay
3.0 star property
24.7 km from Santa Ana
7.4 out of 10, Good, (238 reviews)
"The balcony view was a little scenic. Enjoyed how clean the rooms were "
United States
Rosa
The price is P2,032
P2,479 total
includes taxes & fees
Mar 4 - Mar 5
Villas Santander - Deluxe Stay
Reception

In & Out Hotel

In & Out Hotel
3.0 star property
20.9 km from Santa Ana
8.6 out of 10, Excellent, (832 reviews)
"Close to the airport, very convenient"
Canada
Lucien
The price is P3,032
P3,699 total
includes taxes & fees
Mar 10 - Mar 11
In & Out Hotel
Terrace/patio

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,004 reviews)
"Beautiful place to stay with amazing views! "
United States
Nate
The price is P6,551
P7,992 total
includes taxes & fees
Mar 8 - Mar 9
Tikal Futura Hotel & Convention Center
Reception

EL TEJAR HOSTAL

EL TEJAR HOSTAL
3.0 star property
21 km from Santa Ana
8.4 out of 10, Very Good, (19 reviews)
"Staff very friendly and helpful. Room clean and quiet. "
United States
ILEANA
The price is P2,303
P2,809 total
includes taxes & fees
Mar 3 - Mar 4
EL TEJAR HOSTAL
Indoor pool, outdoor pool, sun loungers

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (135 reviews)
"The property is absolutely gorgeous and the staff is wonderful. On site restaurant is small but a decent amount to select from to eat. Rooms are clean and comfortable. "
United States
Rochelle
The price is P7,785
P9,497 total
includes taxes & fees
Mar 18 - Mar 19
Kawilal Hotel
Iron/ironing board, free WiFi

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
8.8 out of 10, Excellent, (155 reviews)
"A very nice place to stay is to the airport and quite place love it "
United States
Wilfredo
The price is P3,164
P3,860 total
includes taxes & fees
Mar 23 - Mar 24
Casa Aurora
Outdoor banquet area

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,236 reviews)
"The staff and the rooms are perfect for my family."
Canada
Kingshuk
The price is P5,955
P7,266 total
includes taxes & fees
Mar 29 - Mar 30
Barceló Guatemala City
Interior

Inari Guatemala

Inari Guatemala
3.0 star property
20.8 km from Santa Ana
9.0 out of 10, Wonderful, (90 reviews)
"the room was clean and spacious"
United States
Lawrence
Inari Guatemala
Free WiFi, bed sheets

Hostal Donde Regina

Hostal Donde Regina
3.0 star property
21 km from Santa Ana
9.2 out of 10, Wonderful, (181 reviews)
"Spotless room and good staff service"
United States
Christian
The price is P2,774
P3,385 total
includes taxes & fees
Mar 3 - Mar 4
Hostal Donde Regina
Terrace/patio

L Aurora Inn

L Aurora Inn
3.0 star property
21 km from Santa Ana
8.8 out of 10, Excellent, (115 reviews)
"Clean great locations close to airport breakfast was delicious ."
United States
Jackeline
The price is P4,171
P6,144 total
includes taxes & fees
Mar 31 - Apr 1
L Aurora Inn
View from property

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,007 reviews)
"Great location and pricing."
United States
JULIO
The price is P6,323
P7,714 total
includes taxes & fees
Mar 27 - Mar 28
AC Hotel by Marriott Guatemala City
Flat-screen TV

Casa Mesa

Casa Mesa
2.0 star property
24.3 km from Santa Ana
8.6 out of 10, Excellent, (36 reviews)
"Very good option for staying "
United States
Adrian
The price is P2,600
P3,171 total
includes taxes & fees
Mar 3 - Mar 4
Casa Mesa
Exterior

La Capitania de San Pedro

La Capitania de San Pedro
2.5 star property
2.9 km from Santa Ana
9.2 out of 10, Wonderful, (15 reviews)
"Very nice hotel, nice people "
United States
leonel
The price is P4,244
P5,178 total
includes taxes & fees
Mar 3 - Mar 4
La Capitania de San Pedro
Exterior

Hotel y Restaurante Vista Verde

Hotel y Restaurante Vista Verde
3.0 star property
5.9 km from Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "
United States
Sergio
The price is P3,477
P4,242 total
includes taxes & fees
Mar 17 - Mar 18
Hotel y Restaurante Vista Verde
Interior

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (244 reviews)
"Staff very pleasant and service oriented "
Canada
osbin
The price is P8,649
P10,552 total
includes taxes & fees
Mar 6 - Mar 7
Hotel Vista Quince
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Palacio de los Capitanes
Photo by Jacques Cramatte
Open Photo by Jacques Cramatte

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Casa Buho B&B

Casa Buho B&B

10/10 Excellent
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
Patrick 3-night trip
Posted 2 days ago
Casa Buho B&B

Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 15 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.