Ancient monastery corridors adorned with art lead to a serene spa offering chocolate and jade stone massages. Guests can unwind in the beautiful pool area amid lush gardens and colonial architecture. The restaurant serves local cuisine with enchanting live piano music in the evening.
Popular amenities
Pet friendly
Air conditioning
The current price is P14,721
P14,721
P18,713 total
includes taxes & fees
Jun 21 - Jun 22
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Luxury boutique hotel near Casa Santo Domingo Museum
Close to Antigua Guatemala Cathedral and Central Park, Hotel Museo Spa Casa Santo Domingo provides a poolside bar, a terrace, and a garden. Indulge in a facial, a body treatment, and a body scrub at the onsite spa. At the two on-site restaurants, enjoy breakfast, lunch, dinner, and Fusion cuisine. Enjoy the health club, as well as activities like ziplining. In addition to a hair salon and dry cleaning/laundry services, guests can connect to free WiFi in public areas.
Other perks at this hotel include:
An outdoor pool
Free self parking
Full breakfast (surcharge), a roundtrip airport shuttle (surcharge), and an electric car charging station
Express check-out, smoke-free premises, and luggage storage
Guest reviews speak highly of the helpful staff and first-rate property condition
Room features
All 132 rooms include comforts such as fireplaces and premium bedding, as well as perks like pillow menus and air conditioning.
Extra conveniences in all rooms include:
Rollaway/extra beds (surcharge) and cribs/infant beds (surcharge)
Check-in start time: 3:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 18
Check-out
Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets allowed for an extra charge of USD 61 per pet, per night
Welcoming dogs only
1 total (up to 25 lbs per pet)
Pets cannot be left unattended
Restrictions apply; for more information contact the property at the number on the booking confirmation
Children and extra beds
Children are welcome
Rollaway/extra beds are available for USD 48.8 per day
Cribs (infant beds) are available for USD 9.76 per day
Property payment types
Important information
Optional extras
Fee for full breakfast: approximately USD 20 per person
Airport shuttle fee: USD 60 per person (one-way)
Pet fee: USD 61 per pet, per night
Late check-out is available for a fee (subject to availability)
Crib (infant bed) fee: USD 9.76 per day
Rollaway bed fee: USD 48.8 per day
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and cash
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Some water is reused through a grey water recycling system
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
This property charges a fee of USD 45 per night for use of the sofabed.
We should mention
This property does not have elevators
Reservations are required for massage services and spa treatments; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Guests under 18 years old are not allowed in the spa
Frequently asked questions
Does Hotel Museo Spa Casa Santo Domingo have a pool?
Yes, this property has an outdoor pool.
How much does it cost to stay at Hotel Museo Spa Casa Santo Domingo?
As of May 21, 2026, prices found for a 1-night stay for 2 adults at Hotel Museo Spa Casa Santo Domingo on Jun 21, 2026 start from P14,721, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Hotel Museo Spa Casa Santo Domingo pet-friendly?
Yes, Hotel Museo Spa Casa Santo Domingo allows dogs (limit 1 total) with a maximum weight of up to 25 lbs per pet. There's a fee of USD 61 per pet, per night. Some restrictions may apply, so please contact the property for more details.
How much is parking?
Self parking is free at this property.
What time is check-in at Hotel Museo Spa Casa Santo Domingo?
Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Hotel Museo Spa Casa Santo Domingo?
Check-out is at noon. Late check-out is available for a fee (subject to availability).
Does Hotel Museo Spa Casa Santo Domingo provide a shuttle to the airport?
Yes, there's an airport shuttle. A fee of USD 60 per person applies.
Where is Hotel Museo Spa Casa Santo Domingo located?
Located in Barrio de La Concepción, this luxury hotel is within a 10-minute walk of Casa Santo Domingo Museum, Central Park, and Antigua Guatemala Cathedral. Iglesia y Convento de Santo Domingo and Jade Maya Factory and Museum are just steps away.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Reviews
9.2
Wonderful
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
The most enchanting hotel Iāve ever had the privilege to stay in. We adored the antique-adorned decor, the beautiful breakfast, interacting with the warm staff, enjoying the pools, discovering the museums.
eve
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Clarissa
Apr 13, 2026
The hotel is just imersed with history. The staff was outstanding
The room was amazing. So comfy, and cozy. I would definitely come back . It is in my top 2 hotels to stay at. Food is amazing. It started to down poor and it was so convenient that we could eat at the hotel. Room service is also amazing and fast.
This is definitely one of the best hotels in Antigua, Guatemala. It's such a lovely setting, the ambiance, the amenities, the room, all wonderful. Friendly and courteous staff make you feel at home. A bonus is that you can park your car before you check in, and everything is within walking distance, which saves the hassle of finding parking around Antigua, which can be quite challenging. I definitely recommend staying here!
This was probably one of the most beautiful hotels I've ever stayed in! The grounds and rooms are just absolutely stunning and well-maintained. The service and staff was impeccable. We would absolutely stay here again!
Great Breakfast Buffet. The hotel is in the entrance of Antigua, so it“s about 4,000 steps from the Cathedral and the park (where restaurants and coffe shops are). Nice rooms (clean, TV, bathtub, etc). The Hotel has abot 3 museums inside. This hotel was build on a ancient catholic convent where monks and priests lived their religious life. There are catacombs with the remains of the people that lived there. Trully, the only real 5 star hotel in Central America.
Amazing property beautiful views and grounds large spacious room w a jacuzzi! Lovely staff and restaurant i wish i had more time in antigua and could check out the spa! Ill be back and stay here again
Everything was great, the staff very nice and the food was very tasty. We love to stay at Santo Domingo
Marie Andree
Stayed 2 nights in Nov 2025
Verified
10/10 Excellent
Gregory
Jan 17, 2026
Liked: Cleanliness, staff & service, amenities
This hotel is amazing ⦠and is, perhaps, our favorite hotel in the world. It is unique and historic and unforgettable. We love the fireplace in the room and the heated pool. We stay here every time we visit Antigua, and we love it more each time we stay.