San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo

Popular places to visit

Things to do


Top hotels in San Francisco

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is P10,672 per night from Mar 8 to Mar 9
P10,672
P11,739 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,025 reviews)
Well managed luxury hotel

Reviewed on Feb 10, 2026

Las Americas Golden Tower Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is P7,711 per night from Feb 20 to Feb 21
P7,711
P8,482 total
Feb 20 - Feb 21
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (1,003 reviews)
Great staff

Reviewed on Jan 15, 2026

Sheraton Grand Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is P6,887 per night from Mar 14 to Mar 15
P6,887
P7,576 total
Mar 14 - Mar 15
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,008 reviews)
Perfecto

Reviewed on Feb 8, 2026

Courtyard by Marriott Panama Multiplaza Mall
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is P6,318 per night from Mar 6 to Mar 7
P6,318
P6,950 total
Mar 6 - Mar 7
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.2/10 Wonderful! (2,170 reviews)
Everything was great@

Reviewed on Feb 3, 2026

Plaza Paitilla Inn Hotel
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is P6,635 per night from Feb 28 to Mar 1
P6,635
P7,299 total
Feb 28 - Mar 1
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,545 reviews)
Great location

Reviewed on Feb 8, 2026

Decapolis Hotel Panama City
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is P17,499 per night from Mar 7 to Mar 8
P17,499
P19,249 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,005 reviews)
Beautiful hotel, great service. Breakfast buffet is amazing.

Reviewed on Jan 29, 2026

JW Marriott Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Multiplaza Pacific Mall or Avenida Balboa.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


San Francisco